Reduction of crayfish activity and light avoidance in response to artificial light at night [0.03%]
人工夜光照射下小龙虾活动减弱和避开光源响应
Katelyn Boyle,Abigail Zagar,Catherine Stewart et al.
Katelyn Boyle et al.
The prevalence of artificial light at night can alter nocturnal environments and affect animal behavior. We investigated how the presence of artificial light affects the activity of the variable crayfish Cambarus latimanus by manipulating l...
Characterization and Radiation Response of Cancer-Associated Fibroblasts isolated from Glioblastoma [0.03%]
胶质母细胞瘤来源的癌症相关成纤维细胞的特征及放射反应
Caroline Delmas,Elisabeth Cohen-Jonathan-Moyal,Catherine Seva
Caroline Delmas
Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis and strong resistance to radiotherapy. While cancer-associated fibroblasts (CAFs) are known in epithelial cancers, their presence in GBM has only recently been identified. ...
Megan E Lawson,Jakob Christian,Ryan J Dufur et al.
Megan E Lawson et al.
Gene model for the ortholog of Regulator of cullins 1a ( Roc1a ) in the Drosophila simulans May 2017 (Princeton ASM75419v2/DsimGB2) Genome Assembly (GenBank Accession: GCA_000754195.3). This ortholog was characterized as part of a developin...
Activation of the Arabidopsis thaliana GCN2-eIF2α module by salicylic acid: Biochemical and phenotypic similarities between gcn2 mutant and wild type [0.03%]
水杨酸活化拟南芥的ATGCN2-EIF2Α模块：gcn2突变体和野生型的生化及表型相似性分析
Morgan Wynn,Ansul Lokdarshi,Daniel Rincon Diaz
Morgan Wynn
Plants rely on arsenal of defenses to combat numerous stresses. Salicylic acid (SA) is a crucial hormone in plant defense, yet its role in translational regulation is underexplored. We investigated the SA signaling through the stress sentin...
Identification and functional analysis of ULP2 SUMO protease mutants of the stress-tolerant yeast Kluyveromyces marxianus [0.03%]
耐逆性强的酵母马克斯克鲁维酵母ULP2 SUMO蛋白酶突变体的鉴定及功能分析
Catherine Hutson,Samuel Li,Keegan Sweeney et al.
Catherine Hutson et al.
K. marxianus ( Km ), a stress-tolerant yeast, is closely related to S. cerevisiae ( Sc ). Unlike Sc , Km yeast grows robustly in the presence of proteotoxic stressors, including temperatures up to 45°C and oxidizing agents. Sumoylation, th...
Juvenile hormone mimics induce a cellular immune response in Drosophila melanogaster [0.03%]
保幼激素类似物诱导果蝇的细胞免疫反应
Thuan Luu,Johnny R Ramroop,Min Kyung Lee et al.
Thuan Luu et al.
It is well-known that exposure to juvenile hormone mimics induces a variety of aberrant developmental and physiological effects in insects. One such effect in Drosophila melanogaster is the appearance of melanized tumor-like structures in l...
The two coiled-coil domains of the fission yeast kinesin-6 Klp9 are required for motor tetramerization and spindle elongation [0.03%]
裂殖酵母激酶6Klp9的两个卷曲螺旋结构域可使马达四聚化并实现纺锤体伸长
Mason T Nguyen,Liang Ji,Phong T Tran
Mason T Nguyen
The fission yeast kinesin-6 Klp9 localizes to the spindle midzone at anaphase to produce sliding forces to elongate the bipolar spindle. In the absence of Klp9 , anaphase spindle elongation is attenuated by half its normal rate. Klp9 functi...
Replication of seizure-suppressing effects of alpha-linolenic acid on the Drosophila melanogaster para Shudderer mutant [0.03%]
α-亚麻酸在果蝇para突变体中抗惊厥作用的验证
Samantha Dinnel,Brady Weimer,Allyson Davis et al.
Samantha Dinnel et al.
Voltage-gated sodium channels are essential for healthy nervous system function. Mutations in voltage-gated sodium channels are associated with a range of seizure conditions. The genetics of seizure conditions are complex and often challeng...
Cells stably expressing shRNA against MYO10 display altered cell motility [0.03%]
稳定表达靶向MYO10的shRNA的细胞表现出细胞运动性改变
Joanna A Mas,Chase E Cristella,Vu Hao M N Phan et al.
Joanna A Mas et al.
Myosin-X (MYO10) is an actin-based motor protein involved in cytoskeletal dynamics, membrane interactions, and integrin-mediated adhesion. To investigate MYO10's cellular roles, we generated MYO10 knockdown (MYO10 KD ) HeLa and COS7 cell li...
Leif R Neitzel,Hussain F Basrai,Charles C Hong et al.
Leif R Neitzel et al.
MUC5AC hypersecretion exacerbates airway obstruction in lung diseases, such as asthma, and promotes tumor growth. The expression of MUC5AC is driven by the pH-sensing receptor, GPR68. Herein we demonstrate that acidification (pH 6.4) increa...