Glutathione-Related Metabolite Levels and Enzyme Activities in Depression: A Systematic Review and Meta-Analysis [0.03%]
抑郁症中的谷胱甘肽相关代谢物水平和酶活性：系统评价与荟萃分析
Takahide Etani,Nobuaki Hondo,Sho Moriguchi et al.
Takahide Etani et al.
Recently, an increasing number of studies have reported abnormal levels of glutathione (GSH)-related metabolites and enzyme activities in neuroimaging and peripheral samples in patients with depression, indicating abnormalities in the GSH c...
Context-Dependent Temporal Changes in Hypnotics Involved in Suicide Attempts [0.03%]
与自杀企图有关的催眠药的时间变化取决于上下文
Taro Sasaki,Norio Sugawara,Motoharu Furukawa et al.
Taro Sasaki et al.
Background: Recent prescribing practices have shifted from benzodiazepines (BZs) toward non-GABAergic hypnotics, including dual orexin receptor antagonists (DORAs) and melatonin receptor agonists (MRAs). We examined wheth...
Multicenter Study
Neuropsychopharmacology reports. 2026 Jun;46(2):e70126. DOI:10.1002/npr2.70126 2026
Age and Overdose at the Index Attempt Predict Suicide Reattempts After Emergency Admission: A Multicenter Cohort Study [0.03%]
首次自杀未遂的年龄和过量服用药物预测急诊留观后的重复自杀企图：一项多中心队列研究
Taro Sasaki,Norio Sugawara,Motoharu Furukawa et al.
Taro Sasaki et al.
Aim: A history of suicide attempts is a well-established predictor of future suicidal behavior; however, longitudinal evidence from real-world emergency settings remains limited. Because age and self-poisoning/overdose ar...
Multicenter Study
Neuropsychopharmacology reports. 2026 Jun;46(2):e70127. DOI:10.1002/npr2.70127 2026
Transcranial Calcium Macro-Imaging From the Auditory Cortex of Thy1-Cre-Driven GCaMP8 Transgenic Rats [0.03%]
听皮层Thy1-GCaMP8转基因大鼠的颅外钙信号宏观成像
Manavu Tohmi,Hisaaki Namba,Meiko Kawamura et al.
Manavu Tohmi et al.
Background: Genetically encoded calcium indicators such as GCaMP enable us to monitor neuronal activities from living animals at synaptic levels as well as at whole-brain levels. However, the genetic variation of GCaMP tr...
Distinct Effects of Nonselective Rho-Kinase Inhibitor Fasudil and Selective Rho-Kinase 2 Inhibitor KD025 on Serotonin and Dopamine Release in the Nucleus Accumbens of Mice [0.03%]
非选择性Rho激酶抑制剂 fasudil 和选择性Rho激酶2抑制剂KD025对小鼠伏核多巴胺和五羟色胺释放的分离效应
Rinako Tanaka,Wenjun Zhu,Taku Nagai et al.
Rinako Tanaka et al.
Recent studies have indicated that the Rho GTPase family and Rho-kinases are associated with psychiatric diseases, such as schizophrenia. Two subtypes of Rho-kinase, Rho-kinases 1 and 2, regulate actin dynamics and mediate neurite outgrowth...
Associations Between Serum Adipokine, Antipsychotic Exposure, and Clinical Characteristics in Chronic Schizophrenia: A Cross-Sectional Study [0.03%]
慢性精神分裂症患者血清脂联素、抗精神病药物暴露与临床特征横断面研究的关联性分析
Yasuhiro Ohno,Kiyomi Saito,Keita Hanabusa et al.
Yasuhiro Ohno et al.
Background: Previous meta-analyses have reported lower serum adiponectin levels in patients with schizophrenia treated with second-generation antipsychotics. However, the relationships among serum adipokines, psychiatric ...
Akathisia Induced by Metoclopramide in a Pregnant Woman With Nausea and Vomiting: A Case Report [0.03%]
甲氧氯普胺所致妊娠女性剧吐恶阻的急查报告：病例报告
Ryohei Nakamura,Keisuke Noto,Toshinori Shirata et al.
Ryohei Nakamura et al.
Background: Nausea and vomiting are common during pregnancy and can significantly impair maternal well-being. Metoclopramide is widely used to treat these symptoms but may cause extrapyramidal side effects, including akat...
Japanese Cohort Study Identifies an Association Between the Serotonin Transporter-Linked Polymorphic Region and Suicide Death [0.03%]
日本前瞻性队列研究发现血清素转运蛋白基因多态性与自杀死亡相关
Shohei Okada,Toshiyuki Shirai,Masao Miyachi et al.
Shohei Okada et al.
Introduction: More than 720 000 individuals die by suicide annually worldwide, making it a major public health concern and a leading cause of death among young people, particularly in Asian populations. Dysregulation of t...
Pain-Related Smoking Expectancies Across Tobacco Product Use Patterns, Including Heated Tobacco Products: Psychometric Validation of the Japanese Pain and Smoking Inventory [0.03%]
日本疼痛和吸烟文库的量表学验证：包括加热烟草产品的各种烟草产品使用者中的疼痛相关预期效应
Keiko Yamada,Takashi Kimura,Naoki Mizunuma et al.
Keiko Yamada et al.
Aim: With the rapid proliferation of heated tobacco products (HTPs) in Japan, understanding pain-related smoking expectancies across tobacco use patterns has become increasingly important. In this study, we aimed to profi...
Effects of Repeated Smoking and Quitting Cigarettes on Plasma Concentrations of Clozapine and Its N-Desmethyl and N-Oxide Metabolites in a Japanese Patient With Schizophrenia [0.03%]
重复吸烟及戒烟对一名日本精神分裂症患者氯氮平及其代谢产物血浆浓度的影响
Kazuro Ikawa,Norifumi Morikawa,Mutsumi Sakata et al.
Kazuro Ikawa et al.
Clozapine (CLZ) is used for treatment-resistant schizophrenia. However, its pharmacokinetics in Japanese patients with schizophrenia have not been well described. Smoking affects the activities of cytochrome P450 (CYP), which mainly metabol...