Possible Contribution of Multiple Sclerosis Pathology to Treatment-Resistant Schizophrenia: A Case Study [0.03%]
多发性硬化病理学可能与难治性精神分裂症有关：一例研究报告
Sho Miura,Atsuko Nagaoka,Mizuki Hino et al.
Sho Miura et al.
Multiple sclerosis (MS) can present with neurological and psychiatric symptoms that may overlap with those of schizophrenia, making differentiation difficult particularly because their typical onset ages are similar. We present the case of ...
Trial-History Effects During WCST in Treatment-Resistant Schizophrenia [0.03%]
难治性精神分裂症患者WCST过程中既往治疗史效应的影响
Ryo Sawagashira,Atsuhito Toyomaki,Hayato Watanabe et al.
Ryo Sawagashira et al.
Aim: Treatment-resistant schizophrenia (TRS) is a clinically important subtype of schizophrenia, but its cognitive characteristics remain incompletely understood. The Wisconsin Card Sorting Test (WCST) is widely used to a...
Is Aripiprazole an Effective Adjunct to Reduce Metabolic Adverse Effects Caused by Clozapine in Patients With Schizophrenia-A Systematic Review [0.03%]
阿立哌唑联用氯氮平可否减少精神分裂症患者的代谢不良反应：一项系统综述
Avtaar Singh,Soban Sadiq
Avtaar Singh
Clozapine is an atypical antipsychotic used in the treatment of schizophrenia. However, its use is associated with significant metabolic adverse effects, including hyperglycaemia, dyslipidaemia, and weight gain. Aripiprazole, a newer atypic...
The "GABAergic Brake" on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine- and Benzodiazepine-Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome [0.03%]
胆碱能抗胆碱作用对脊髓排便反射的作用：“五羟色胺受体在消化道平滑肌中过度表达导致某些抗精神病药物诱发的胃肠运动功能障碍及奥格列夫氏综合征”的神经生物学假说模型
Takahiko Nagamine
Takahiko Nagamine
Synergistic "Double Brake" Model on the Spinal Defecation Center in Clozapine-Induced Constipation. Real-world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and ma...
Digital and Biomarker-Based Monitoring for Schizophrenia-Treatment Adherence [0.03%]
数字化和生物标志物监测在精神分裂症治疗依从性中的作用
Samuel Inshutiyimana,Kush Rajeshbhai Rana,Michael Matiop Aleu et al.
Samuel Inshutiyimana et al.
Background: Nonadherence to antipsychotics affects nearly half of patients with schizophrenia, leading to rehospitalization, suicidality, and reduced quality of life. Optimizing treatment adherence is critical to prevent ...
Problematic Internet Use and Family Rules Among Children and Adolescents [0.03%]
儿童青少年问题性互联网使用及其家庭规则特点研究
Saya Moriyama,Takayuki Harada
Saya Moriyama
This study investigates the relationship between problematic Internet use (PIU) and family rules regarding Internet use among children and adolescents. Although the Internet offers valuable development opportunities, excessive use is associ...
Association Between Participant Satisfaction and Self-Reported Clinical Practice Behaviors in a Nationwide Guideline Education Program [0.03%]
全国指南教育项目中参与者满意度及其报告的临床实践行为之间的关联性研究
Kazuhiko Yamamuro,Kenta Ide,Yusuke Arai et al.
Kazuhiko Yamamuro et al.
Background: Educational interventions are widely used to promote guideline-concordant psychiatric practice. However, it remains unclear whether participants' subjective satisfaction translates into actual changes in clini...
Observational Study
Neuropsychopharmacology reports. 2026 Sep;46(3):e70147. DOI:10.1002/npr2.70147 2026
Epilepsy-Related Psychosis in Drug-Resistant Epilepsy With Nonconvulsive Status Epilepticus and Difficult Antipsychotic Titration: A Case Report [0.03%]
难治性癫痫伴非惊厥性癫痫持续状态和难治性抗精神病药诱发的精神病一例报告
Wataru Omori,Ryo Hirabayashi,Kenichi Oga et al.
Wataru Omori et al.
Introduction: Psychosis in epilepsy may be difficult to diagnose when altered consciousness, antiseizure medication changes, and psychotropic adverse effects coexist. ...
Comment on "Serum Amyloid β Oligomer May Predict Treatment Response in Middle-Aged and Late-Life Patients With Depression" [0.03%]
关于“血清淀粉样β寡聚体可能预测中年和老年人抑郁患者的治疗反应”的评论
Stjepan Škudar
Stjepan Škudar
Serum Aβ oligomer positivity may indicate neurodegenerative vulnerability and may be associated with poorer antidepressant treatment response in middle-aged and late-life depression. Further validation using amyloid PET, tau biomarkers, st...
UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Autism Spectrum Disorder [0.03%]
英国大麻药物登记处自闭症谱系疾病的临床结果分析
Arushika Aggarwal,Simon Erridge,Madhur Varadpande et al.
Arushika Aggarwal et al.
Introduction: Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with distressed behaviors and psychological challenges. This study aims to evaluate the change in health-related quality of life (HR...
Observational Study
Neuropsychopharmacology reports. 2026 Sep;46(3):e70146. DOI:10.1002/npr2.70146 2026