Mesenchymal stem cells attenuate keloid pathogenesis via TGF-β1/SMAD-driven MMP9 suppression: mechanistic insights into collagen remodeling and extracellular matrix homeostasis [0.03%]
间充质干细胞通过TGF-β1/SMAD驱动的MMP9抑制来减轻瘢痕增生的发病机制：关于胶原重塑和细胞外基质稳态的机制见解
Yujia Zhao,Hexiao Zhang,Qiuyan Han et al.
Yujia Zhao et al.
Keloids, characterized by excessive collagen deposition and recurrence, pose significant therapeutic challenges due to limited mechanistic understanding. Mesenchymal stem cells (MSCs) exhibit potential for keloid management, but their preci...
Single-cell profiling of long non-coding RNAs in the hematopoietic system [0.03%]
血液系统长非编码RNA单细胞谱系追踪及功能研究
Yu Zhang,Qiuju Huang,Yawen Zhang et al.
Yu Zhang et al.
Long non-coding RNAs (lncRNAs) play a crucial role in normal and dysregulated hematopoiesis. However, the functional repertoire of lncRNAs across various hematopoietic cell types remains elusive. In this study, we constructed a comprehensiv...
The evolution of artificial red blood cells and recent advances in state-of-the-art oxygen carrier technologies: a narrative review [0.03%]
人造红细胞的发展和先进携氧载体技术的最新进展：叙述性综述
Trasha Shetty,Anshuman Darbari
Trasha Shetty
The demand for homologous blood transfusions has reached an unprecedented level, driven by a declining donor population and the ever-increasing need for blood products. While significant advancements have been made in medical equipment and ...
Daratumumab in relapsed or refractory immune thrombocytopenic purpura [0.03%]
达雷木单抗治疗复发或难治性免疫性血小板减少症患者的疗效
Ciprian Tomuleasa,Robert Peter Gale
Ciprian Tomuleasa
China Expert consensus on the application of metagenomic next-generation sequencing for the etiological diagnosis of infections in hematological disorders (2024) [0.03%]
中国血液系统疾病感染病原体宏基因组下一代测序技术病因诊断应用专家共识（2024）
Chunhui Xu,Ren Lin,Ye Bai et al.
Chunhui Xu et al.
Infections are frequent complications in patients with hematological disorders, and pathogen diagnosis remains challenging. Metagenomic next-generation sequencing (mNGS) is an unbiased high-throughput technology that has been widely applied...
Chun-Hui Jin,Yang Tang,Limei Qu et al.
Chun-Hui Jin et al.
Alpha-enolase promotes progression of acute myeloid leukemia via MAPK/ERK signaling pathway [0.03%]
α烯醇化酶通过MAPK / ERK信号通路促进急性髓系白血病的发展进展
Shanshan Zhang,Haina Wang,Xuehong Zhang et al.
Shanshan Zhang et al.
Due to the limited availability of effective treatment therapies, patients with refractory and relapsed acute myeloid leukemia (AML) often have poor prognoses. Therefore, identifying new therapeutic targets to improve the treatment landscap...
Linjuan Wang,Shaowei Qiu
Linjuan Wang
Chimeric antigen receptor (CAR) T-cell therapy is an epoch-making immunotherapy for the treatment of relapsed or refractory (r/r) blood tumors, as demonstrated by its successful implementation in r/r B cell-derived malignancies. However, re...
Daratumumab in children with advanced idiopathic thrombocytopenic purpura [0.03%]
儿童难治性特发性血小板减少性紫癜接受达雷木单抗治疗的安全性和有效性研究
Robert Peter Gale
Robert Peter Gale
Challenges and advances in prenatal diagnosis and management of beta thalassemia in Pakistan [0.03%]
巴基斯坦输血浆症产前诊断和处理的挑战与进展
Muhammad Suleman Ur Rehman,Sadiq Murtaza Sheriff,Muhammad Mahad Riaz et al.
Muhammad Suleman Ur Rehman et al.