Seema Emami,Eirini Kaisari,Timothy M Janetos
Seema Emami
Comparison between sodium iodate and lipid peroxide murine models of age-related macular degeneration for drug evaluation-a narrative review [0.03%]
用于药物评价的年龄相关性黄斑变性的亚硝酸钠模型和脂质过氧化模型比较-综述性质的文章
Soo-Young Kim,Haohua Qian
Soo-Young Kim
Objective: In this review, non-transgenic models of age-related macular degeneration (AMD) are discussed, with focuses on murine retinal degeneration induced by sodium iodate and lipid peroxide (HpODE) as preclinical stud...
RegenX: an NLP recommendation engine for neuroregeneration topics over time [0.03%]
RegenX：一个用于随时间推荐神经再生主题的NLP推荐引擎
Shaan Khosla,Leila Abdelrahman,Joseph Johnson et al.
Shaan Khosla et al.
Background: In this investigation, we explore the literature regarding neuroregeneration from the 1700s to the present. The regeneration of central nervous system neurons or the regeneration of axons from cell bodies and ...
Alexandra Rosario,Ashley Howell,Sanjoy K Bhattacharya
Alexandra Rosario
In the early days of deciphering the injured neuronal tissues led to the realization that contrast is necessary to discern the parts of the recovering tissues from the damaged ones. Early attempts relied on available (and often naturally oc...
Innovations in the diagnosis and management of uveitis: promising research to address unmet patient needs [0.03%]
创新的诊断和治疗葡萄膜炎方法：有希望的研究以满足患者的未竟需求
Steven Yeh,Ye Huang,Joanne Thomas
Steven Yeh
Sodium iodate-induced retina degeneration observed in non-separate sclerochoroid/retina pigment epithelium/retina whole mounts [0.03%]
碘酸钠诱发视网膜变性的研究非分离巩膜脉络膜/色素上皮/视网膜整片观察
Soo-Young Kim,Yang Zhao,Hong-Lim Kim et al.
Soo-Young Kim et al.
Background: Sodium iodate (SI) is a chemical widely applied to induce retina degeneration in animal models. SI treatment caused formation of rosettes/folds in the outer nuclear layer (ONL) of the rat retina, but it was pr...
Cytomegalovirus retinitis in the highly active anti-retroviral therapy era [0.03%]
高效抗逆转录病毒治疗时代的眼巨细胞病毒感染
Ifeoma N Ude,Steven Yeh,Jessica G Shantha
Ifeoma N Ude
Cytomegalovirus (CMV) retinitis is an opportunistic infection that has traditionally affected those who have HIV/AIDS or immunosuppressed individuals. CMV retinitis previously infected one-third of AIDS patients in the pre-highly active ant...
Ogul E Uner,Nikhila Gandrakota,Corrina P Azarcon et al.
Ogul E Uner et al.
Animal models are crucial for the study of tumorigenesis and therapies in oncology research. Though rare, uveal melanoma (UM) is the most common intraocular tumor and remains one of the most lethal cancers. Given the limitations of studying...
Combined automated screening for age-related macular degeneration and diabetic retinopathy in primary care settings [0.03%]
初级保健环境中年龄相关性黄斑变性和糖尿病视网膜病变的联合自动化筛查
Alauddin Bhuiyan,Arun Govindaiah,Sharmina Alauddin et al.
Alauddin Bhuiyan et al.
Background: Age-related macular degeneration (AMD) and diabetic retinopathy (DR) are among the leading causes of blindness in the United States and other developed countries. Early detection is the key to prevention and e...
Characteristics of normal human retinal pigment epithelium cells with extremes of autofluorescence or intracellular granule count [0.03%]
极端自发荧光或细胞内颗粒计数的正常人视网膜色素上皮细胞的特点
Katharina Bermond,Andreas Berlin,Ioana-Sandra Tarau et al.
Katharina Bermond et al.
Background: Cells of the retinal pigment epithelium (RPE) accumulate different kinds of granules (lipofuscin, melanolipofuscin, melanosomes) within their cell bodies, with lipofuscin and melanolipofuscin being autofluores...