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Characteristics of normal human retinal pigment epithelium cells with extremes of autofluorescence or intracellular granule count

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Background: Cells of the retinal pigment epithelium (RPE) accumulate different kinds of granules (lipofuscin, melanolipofuscin, melanosomes) within their cell bodies, with lipofuscin and melanolipofuscin being autofluorescent aft... ...