sFlt-1/PlGF and Beyond: Angiolymphatic-Associated Signatures and Emerging Biomarkers in Placental Pathology [0.03%]
胎盘病理学中的血管淋巴标志物和新兴生物标志物：sFlt-1/PlGF之外
Dr Seetu Palo,Dr Mishu Mangla,Dr Rohini Motwani
Dr Seetu Palo
The placenta is a highly vascularized organ that depends on tightly regulated angiolymphatic networks to sustain normal fetal growth and maternal adaptation to pregnancy. Disruption of these pathways contributes to major obstetric complicat...
Integrating Endothelium-Derived Hyperpolarization, Nitric Oxide, and Prostacyclin Pathways: The Multimodal Potential of Human Tissue Kallikrein-1 [0.03%]
人组织激肽原酶1的多功能性：内皮衍生高极化、一氧化氮和前列环素途径的整合
Paolo Madeddu,Styliani Goulopoulou,David Wambeke
Paolo Madeddu
Endothelial cells regulate vascular tone by releasing nitric oxide (NO) and prostacyclin (PGI2), as well as by initiating hyperpolarization of vascular smooth muscle cells through K+ channels and myoendothelial coupling. This review highlig...
ATF6 Inhibition Suppresses the Protective Effects of Pasireotide in Human and Bovine Endothelial Cells [0.03%]
ATF6抑制抑制了帕西罗肽在人和牛内皮细胞中的保护作用
Saikat Fakir,Md Matiur Rahman Sarker,Madan Sigdel et al.
Saikat Fakir et al.
Activating transcription factor 6 (ATF6) is an unfolded protein response (UPR) sensor with a significant role in endothelial integrity and barrier function. This study investigates the effects of Ceapin-A7, which is an ATF6 suppressor, in m...
PHARMACOLOGICAL AND IMMUNOHISTOCHEMICAL CHARACTERIZATION OF DOPAMINE D4 RECEPTOR IN HUMAN UMBILICAL ARTERY AND VEIN [0.03%]
人脐动脉和静脉中多巴胺D4受体的药理学和免疫组化特性研究
Pedro Renato Guazzelli,José Britto-Júnior,Pérola Rafaella Cedano P Souza Godoy et al.
Pedro Renato Guazzelli et al.
Aims - To investigate the effects of the dopamine D4 receptor agonist A-412997 and the D4 antagonist sonepiprazole in human isolated umbilical artery (HUA) and vein (HUV) and the expression of the D4 receptor by immunohistochemistry in thes...
Serum Tissue Plasminogen Activator After Cycling with Blood Flow Restriction [0.03%]
血液流量限制下的自行车运动对组织型纤溶酶原激活物的影响
Josh Landers Landers,Melissa Allen,Ibrahim Oladele et al.
Josh Landers Landers et al.
Blood flow restriction exercise (BFRE) is a therapeutic approach traditionally used to facilitate muscular strength and hypertrophy. Emerging evidence has identified its benefits on other systems and metabolic processes. The emphasis of thi...
Lack of intracranial atherosclerosis in various atherosclerotic mouse models [0.03%]
动脉粥样硬化小鼠模型中缺乏颅内动脉粥样硬化病变
Diewertje Ilse Bink,Katja Ritz,Claire Mackaaij et al.
Diewertje Ilse Bink et al.
Background: Although mice are used extensively to study atherosclerosis of different vascular beds, limited data is published on the occurrence of intracranial atherosclerosis. Since intracranial atherosclerosis is a comm...
Protection of liver sinusoidal endothelial cells using different preservation solutions [0.03%]
不同保存液对肝窦内皮细胞的保护作用
Julia Houtzager,Anne-Marieke D van Stalborch,Charlotte Hofstee et al.
Julia Houtzager et al.
Objective: Donor liver preservation methods and solutions have evolved over the last years. Liver sinusoidal endothelial cell (LSEC) barrier function and integrity during preservation is crucial for outcomes of liver tran...
Whole-body insulin resistance leads to accelerated atherosclerosis: role for Nox2 NADPH oxidase [0.03%]
全身胰岛素抵抗导致动脉粥样硬化加速：Nox2 NADPH氧化酶的作用
Azhar Maqbool,Hema Viswambharan,Anna Skromna et al.
Azhar Maqbool et al.
Insulin resistance underpins the progression of type 2 diabetes mellitus and leads to a collection of risk factors for the development of atherosclerosis. Whether or not insulin resistance at a whole-body level per se leads to accelerated a...
Therapeutic angiogenesis for patients with chronic limb-threatening ischemia: promising or hoax? [0.03%]
慢性肢体缺血患者的治疗性血管生成：前景还是骗局？
Judith A H M Peeters,Abbey Schepers,Jaap F Hamming et al.
Judith A H M Peeters et al.
Chronic limb-threatening ischemia (CLTI) is a critical end-stage disease that leads to high amputation rates. Over the past few decades, therapeutic angiogenesis has attracted a lot of attention as a means to reduce the necessity for amputa...
Ang II-induced contraction is impaired in the aortas of renovascular hypertensive animal model [0.03%]
血管紧张素Ⅱ诱导的收缩在肾血管性高血压动物模型腹主动脉中的作用受损现象研究
Bernah M Fahning,Simone R Potje,Tiago D Paula et al.
Bernah M Fahning et al.
Abstract: Renin-angiotensin system plays a critical role in blood pressure control, and the abnormal activation of the AT1 receptor contributes to the development of renovascular hypertension. This study aimed to evaluate...