Integrating Endothelium-Derived Hyperpolarization, Nitric Oxide, and Prostacyclin Pathways: The Multimodal Potential of Human Tissue Kallikrein-1
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Endothelial cells regulate vascular tone by releasing nitric oxide (NO) and prostacyclin (PGI2), as well as by initiating hyperpolarization of vascular smooth muscle cells through K+ channels and myoendothelial coupling. This review highlights the therapeutic ... ...
