Michael M Lederman,Robert A Bonomo
Michael M Lederman
Ahmed Elshazly,Daniel A Russell,Graham F Hatfull et al.
Ahmed Elshazly et al.
The 2025 Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, supported by the International Antiviral Society-USA, brought over 250 researchers, clinicians, and industry innovators from 17 countries to Washington, DC, from Oc...
Gastrointestinal Mucosal Disruptions During ART-Treated SIV /Plasmodium fragile Co-Infection [0.03%]
ART治疗期间SIV/鼠疟原虫共感染的胃肠道黏膜损伤
Sydney M Nemphos,Hannah C Green,James E Prusak et al.
Sydney M Nemphos et al.
Background: Human immunodeficiency virus (HIV) and Plasmodium spp., which causes malaria, are co-endemic. Previously, we showed that during antiretroviral therapy (ART)-treated simian immunodeficiency virus (SIV)/Plasmodi...
Characterization of Distinct Monocyte Subtypes and Immune Features Associated with HIV, Tuberculosis, and Coronary Artery Disease in a Ugandan Cohort Using Mass Cytometry [0.03%]
利用高维细胞质谱技术表征与艾滋病、结核和冠心病相关的 Uganda 队列中单核细胞亚群及免疫特征
José Cobeña-Reyes,Celestine N Wanjalla,Manuel G Feria et al.
José Cobeña-Reyes et al.
Background: Coronary artery disease (CAD), tuberculosis (TB), and HIV are major global health concerns. Individuals affected by one or more of these conditions often exhibit chronic inflammation and immune dysregulation, ...
Long-Term Follow-Up After Fecal Microbiota Transplantation via Freeze-Dried Capsules for Recurrent Clostridioides difficile Infection [0.03%]
口服冻干菌胶囊粪便微生物移植治疗复发性艰难梭菌感染的长期随访研究
Michelle T Hecker,Christian Rosero,Rafael Mendo-Lopez et al.
Michelle T Hecker et al.
Background: Fecal microbiota transplantation (FMT) is a standard therapy for recurrent Clostridioides difficile infection (CDI). Limited information is available on the durability of response after FMT via freeze-dried or...
Three-Month cART Initiated During Primary HIV Does Not Correct the Structural, Immune, and Microbial Abnormalities within the Gastrointestinal Tract [0.03%]
在HIV急性期开始为期三个月的抗逆转录病毒治疗无法矫正胃肠道内的结构、免疫和微生物异常现象
Camilla Tincati,Valeria Bono,Silvia Nozza et al.
Camilla Tincati et al.
Background: HIV infection leads to profound alterations of gut structure, immunity, and microbiome, resulting in immune activation and inflammation, which drive the development of non-infectious comorbidities. The introdu...
An Era Ended, But the Legacy Lingers On: A Personal Reflection on Dr. David Baltimore [0.03%]
一个时代的结束，但遗产犹在——追忆戴维·巴尔的摩博士
Parameswaran Ramakrishnan
Parameswaran Ramakrishnan
Dr. David Baltimore's contributions to modern biology span more than six decades and continue to shape the fields of virology, immunology, biochemistry, and molecular biology. Beyond his landmark discoveries-such as reverse transcriptase an...
Defects in Innate and Intrinsic Immunity in Morocco: A Retrospective Analysis of the Genetic Landscape and Clinical Correlations [0.03%]
摩洛哥先天性和固有免疫缺陷的遗传景观和临床相关性回顾分析
Marwa Refaat,Chaymae Oujane,Abderrahmane Errami et al.
Marwa Refaat et al.
Background: Susceptibility to common infectious diseases is often linked to innate immune deficiencies. Patients may present normal standard immunological profiles but remain highly vulnerable to infections, complicating ...
Efficacy of Rezafungin on Candida albicans Endophthalmitis in a Rabbit Model [0.03%]
雷扎fungin治疗白色念珠菌兔眼内炎的疗效研究
John Saghir,Janet Herrada,Lisa Long et al.
John Saghir et al.
Background: Endophthalmitis, a severe infection of the intraocular tissues that can result in permanent loss of vision if not immediately treated, is often caused by fungi, namely Candida albicans. Treatment options are l...
Meeting Summary for Keystone Symposia on HIV Cure: Antiretroviral Therapy (ART)-Free Control of HIV Infection in Durban, South Africa, 2025 [0.03%]
艾滋病治愈关键石研讨会会议纪要：在南非德班举办的“无抗逆转录病毒治疗(RVT)控制HIV感染”分会，2025年
Kiho Tanaka,Tatenda Jimmy Blessing Chikowore,Steven G Deeks et al.
Kiho Tanaka et al.
Antiretroviral therapy (ART) can effectively control human immunodeficiency virus (HIV) replication; however, lifelong treatment is required due to viral reservoirs, which fuel viral rebound. This necessitates curative interventions that ca...