A Year in Review on Tuberculosis and Non-tuberculous Mycobacteria Disease: A 2026 Update for Clinicians and Scientists [0.03%]
2026年结核病和非结核分枝杆菌疾病年度进展回顾：临床医师与科研人员必读
Simone Tunesi,Graham Bothamley,Gunar Günther et al.
Simone Tunesi et al.
Background: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, while infections from non-tuberculous mycobacteria (NTM) represent a growing public health threat. In its 20th year of activity, th...
Impact of Sex on Viral Shedding and Symptom Severity During Acute COVID-19 [0.03%]
性别对急性COVID-19病毒释放和症状严重程度的影响
Evelyn Kung,Rinki Deo,Manish C Choudhary et al.
Evelyn Kung et al.
Background: To evaluate the impact of sex on acute SARS-CoV-2 infection, 668 participants from the ACTIV-2/A5401 study were followed over a 28-day period. ...
Michael M Lederman,Leonard H Calabrese
Michael M Lederman
In this interview, Eric Topol, MD, reflects on a career defined by a sustained commitment to patient-centered medicine. He describes his early training in cardiology, mentorship grounded in a humanistic approach, and how adaptability has sh...
Distinct Antibody Fc-profiles in Lymph During Homeostasis and Chronic HIV Infection [0.03%]
慢性HIV感染和稳态期间淋巴组织中抗体的Fc特征不同
Ryan P McNamara,Audrey L Butler,Sepideh Dolatshahi et al.
Ryan P McNamara et al.
Background: Antibodies play a critical role in the control of pathogens and tumors through their ability to recognize non-self and then direct immune-mediated destruction. Antibodies are generated by plasma cells or plasm...
Arturo Casadevall Speaks on Curiosity, Resilience, and Scientific Integrity [0.03%]
卡斯达伐谈好奇心、韧性与科研诚信
Robert A Bonomo,Michael M Lederman
Robert A Bonomo
In this interview, Arturo Casadevall, MD, PhD, shares insight into his childhood, what motivated him to go into biomedical research, the impact of the AIDS epidemic, and the lessons learned that he imparts to younger scientists. ...
A Novel Adaptive Platform for Rapid, Simple Flow-Based Antibody Detection Devices Predicts NAb Levels to SARS-CoV-2 [0.03%]
一种新型自适应平台可快速简便地用于基于流式的抗体检测设备，以预测对SARS-CoV-2的中和抗体水平
Alena J Markmann,D Ryan Bhowmik,Baowei Jiang et al.
Alena J Markmann et al.
Background: COVID-19 has caused millions of deaths and continues to burden individuals and the healthcare system. Antibodies that neutralize SARS-CoV-2 have proven to be the most reliable markers of immune protection, tar...
Michael M Lederman,Robert A Bonomo
Michael M Lederman
2025 Conference on Bacteriophages: Biology, Dynamics, and Therapeutics [0.03%]
2025噬菌体大会：噬菌体的生物学、生态学和治疗学
Ahmed Elshazly,Daniel A Russell,Graham F Hatfull et al.
Ahmed Elshazly et al.
The 2025 Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, supported by the International Antiviral Society-USA, brought over 250 researchers, clinicians, and industry innovators from 17 countries to Washington, DC, from Oc...
Gastrointestinal Mucosal Disruptions During ART-Treated SIV /Plasmodium fragile Co-Infection [0.03%]
ART治疗期间SIV/鼠疟原虫共感染的胃肠道黏膜损伤
Sydney M Nemphos,Hannah C Green,James E Prusak et al.
Sydney M Nemphos et al.
Background: Human immunodeficiency virus (HIV) and Plasmodium spp., which causes malaria, are co-endemic. Previously, we showed that during antiretroviral therapy (ART)-treated simian immunodeficiency virus (SIV)/Plasmodi...
Characterization of Distinct Monocyte Subtypes and Immune Features Associated with HIV, Tuberculosis, and Coronary Artery Disease in a Ugandan Cohort Using Mass Cytometry [0.03%]
利用高维细胞质谱技术表征与艾滋病、结核和冠心病相关的 Uganda 队列中单核细胞亚群及免疫特征
José Cobeña-Reyes,Celestine N Wanjalla,Manuel G Feria et al.
José Cobeña-Reyes et al.
Background: Coronary artery disease (CAD), tuberculosis (TB), and HIV are major global health concerns. Individuals affected by one or more of these conditions often exhibit chronic inflammation and immune dysregulation, ...