The efficacy of home-based virtual reality exposure therapy as an add-on to behavioral therapy for children with selective mutism: Protocol for a single-case experimental design [0.03%]
作为行为治疗补充的基于家庭的虚拟现实暴露疗法治疗选择性缄默症儿童的有效性：单例实验设计研究方案
Wendy van Vlerken,Jeroen S Legerstee,Robert G Belleman et al.
Wendy van Vlerken et al.
Background: Selective Mutism (SM) is a rare childhood anxiety disorder characterized by an inability to speak in specific social situations, despite speaking freely in others. School is typically the environment where the...
Relaxation effects of Shikuwasa (Citrus depressa Hayata) essential oil inhalation: A randomized controlled trial in young adult females [0.03%]
百香果精油吸入缓解年轻女性压力的随机对照研究
Fumitake Yamaguchi,Miho Kuroki,Naoki Yoshinaga et al.
Fumitake Yamaguchi et al.
Background: Shikuwasa (Citrus depressa Hayata) essential oil, rich in limonene and γ-terpinene, produces calming effects, but its psychological and physiological relaxation effects in humans remain unclear. This study ex...
Designing communication strategies to increase rural participation in clinical trials using the Health Belief Model and strategic communication [0.03%]
Dannell Boatman,Stephenie Kennedy-Rea,Jay Mason et al.
Dannell Boatman et al.
•Participants reported slight positive attitudes towards toward clinical trials.•Participants had concerns about safety, benefits, and how to access trials.•Lower socioeconomic groups had lower trust and were less willing to participate....
Pharmacokinetics, safety and preliminary efficacy study of montelukast in critically ill infants with developing bronchopulmonary dysplasia (PRISM) [0.03%]
孟鲁司特治疗支气管肺发育不良高危婴幼儿的药代动力学、安全性和初步疗效研究（PRISM研究）
Jason E Lang,Daniel Gonzalez,Chi D Hornik et al.
Jason E Lang et al.
Bronchopulmonary dysplasia (BPD) is an inflammatory disease stemming from premature birth and iatrogenic lung injury. BPD is relatively common and frequently fatal; despite this, there are no FDA-approved therapies. Montelukast is increasin...
Optimization of patient and site engagement in the SYNCHRONIZE™ phase 3 clinical trial program for survodutide in obesity through clinical trial simulation [0.03%]
通过临床试验模拟优化司維杜肽治疗肥胖症的SYNCHRONIZE™ III期临床试验项目及患者参与度
Domenica M Rubino,Vicki Mooney,Viviënne van de Walle et al.
Domenica M Rubino et al.
Introduction: Clinical trial simulations (CTSs) are an increasingly common way to incorporate site staff and participant feedback into clinical trial design. CTSs can help overcome the unique challenges presented in obesi...
The exercise and concussion health study (TECHS): Pilot and feasibility protocol [0.03%]
关于运动与脑震荡健康的调查(TECHS)：试点和可行性方案
Emma M Tinney,Mark C Nwakamma,Goretti España-Irla et al.
Emma M Tinney et al.
Mild traumatic brain injury (mTBI) is a prevalent neurological condition, affecting millions worldwide, and frequently resulting in persistent cognitive impairment that significantly impacts daily functioning. Current clinical management an...
Effects of intermittent theta-burst stimulation (iTBS) on post-stroke depression (PSD): A study protocol for a single-center randomized controlled trial [0.03%]
间断θ爆发刺激对卒中后抑郁影响的单中心随机对照试验方案：一项研究方案
Yanbiao Zhong,Meng Ren,Wenjing Wang et al.
Yanbiao Zhong et al.
Introduction: Intermittent theta-burst stimulation (iTBS) is a specific type of repetitive transcranial magnetic stimulation (rTMS) paradigm with long-lasting effects and a short session duration. Although randomized cont...
Study protocol for PIANo-1: Personalized Investigation of music's effect on Attention in a series of N-of-1 trials [0.03%]
PIANO-1研究方案：一系列N-of-1试验中音乐对注意力影响的个性化调查
Thomas Gärtner,Fabian Stolp,Bert Arnrich et al.
Thomas Gärtner et al.
Background: Focus and concentration are influenced by various environmental factors, such as listening to music. Recent research highlights the individualized nature of music's effects on concentration, as responses vary ...
Promoting the recruitment of historically underrepresented children and families in clinical trials: Perspectives of pediatric clinic staff [0.03%]
促进临床试验中历来代表性不足的儿童和家庭的招募：儿科诊所工作人员的观点
Janvi D Nanavati,Daniel Mendoza Martinez,Grace W Ryan et al.
Janvi D Nanavati et al.
Introduction: Children and families from historically marginalized ethnic/racial backgrounds have low participation in clinical trials and pediatric practice staff perspectives on this topic are underexplored. ...
An updated review of the SMA clinical trial landscape in the United States: Findings from analysis of recruitment targets on ClinicalTrials.gov and a survey of SMA clinical trial sites on factors affecting site capacity and readiness [0.03%]
美国脊髓性肌萎缩症临床试验现状的更新：来自ClinicalTrials. gov上招募目标分析以及对影响研究中心承接能力与准备性的因素的调查结果
Fatou Sarr,Ilse Peterson,Jacqueline Glascock et al.
Fatou Sarr et al.
The approval of new disease-modifying treatments, diagnostic tools, and expansion of the drug pipeline has evolved the clinical trial landscape for spinal muscular atrophy (SMA) - a rare neuromuscular disease. Nonetheless, significant unmet...