Investigation of the impact of copper nanoparticles coated with ocimum bassilicum at chemoradiotherapy of colon carcinoma [0.03%]
评估圣 basil 罗勒涂层铜纳米颗粒对结肠癌化学放射治疗的影响研究
Farshad Seyed Nejad,Mostafa Alizade-Harakiyan,Mehdi Haghi et al.
Farshad Seyed Nejad et al.
Background: Colon carcinoma poses a significant health challenge globally, particularly in developed nations where sedentary lifestyles, poor dietary choices, and genetic factors play a crucial role in its prevalence. Che...
4-hydroxy-2-oxoglutarate metabolism in a mouse model of Primary Hyperoxaluria Type 3 [0.03%]
原发性高草酸尿症III型小鼠模型中的4-羟基-2-氧代谷氨酸代谢
Xingsheng Li,Owen P Cunneely,Sonia Fargue et al.
Xingsheng Li et al.
Primary Hyperoxaluria Type 3 (PH3) results from 4-hydroxy-2-oxoglutarate (HOG) aldolase (HOGA) deficiency, which causes an increase in endogenous oxalate synthesis leading to calcium oxalate kidney stone disease. The mechanisms underlying H...
Identification of biomarkers related to tryptophan metabolism in osteoarthritis [0.03%]
与骨关节炎色氨酸代谢相关的生物标志物识别
Junjun Yang,Ping Zhou,Tangbing Xu et al.
Junjun Yang et al.
Background: OA (osteoarthritis) is a common joint disease characterized by damage to the articular cartilage and affects the entire joint tissue, with its main manifestations being joint pain, stiffness, and limited movem...
Material-based treatment strategies against intraosseous implant biofilm infection [0.03%]
基于材料的治疗策略对抗骨内种植体生物膜感染
Zhuoer Pan,Chengxin Dai,Weixu Li
Zhuoer Pan
Implant-associated infections present a significant clinical obstacle for orthopedic practitioners, with bacterial biofilm formation serving as a pivotal factor in the initiation, progression, and management of such infections. Conventional...
Renuka Khanzode,Garima Soni,Shalini Srivastava et al.
Renuka Khanzode et al.
Recently, mRNA has gained a lot of attention in the field of vaccines, gene therapy, and protein replacement therapies. Herein, we are demonstrating a comprehensive approach to designing, cloning, and characterizing an antigenic cassette fo...
Yuanxia Zheng,Yi Zhang,Xuegang Li et al.
Yuanxia Zheng et al.
The widely used ET recombination requires an ssDNA product degraded by Rac phage protein E588 from dsDNA for strand invasion. However, proof of the ssDNA product is still elusive. The study provided three levels of proof sequentially. The p...
Quantitative proteome analysis of LAP1-deficient human fibroblasts: A pilot approach for predicting the signaling pathways deregulated in LAP1-associated diseases [0.03%]
LAP1缺陷型人类成纤维细胞蛋白质组定量分析：预测LAP1相关疾病中失调的信号通路的初步方法
Cátia D Pereira,Guadalupe Espadas,Filipa Martins et al.
Cátia D Pereira et al.
Lamina-associated polypeptide 1 (LAP1), a ubiquitously expressed nuclear envelope protein, appears to be essential for the maintenance of cell homeostasis. Although rare, mutations in the human LAP1-encoding TOR1AIP1 gene cause severe disea...
Actin-organizing protein palladin modulates C2C12 cell fate determination [0.03%]
肌动蛋白排列蛋白palladin调控C2C12细胞命运决定
Ngoc Uyen Nhi Nguyen,Ching-Cheng Hsu,Shah R Ali et al.
Ngoc Uyen Nhi Nguyen et al.
Background: Cell confluency and serum deprivation promote the transition of C2C12 myoblasts into myocytes and subsequence fusion into myotubes. However, despite all myoblasts undergoing the same serum deprivation trigger,...
Green synthesis, characterization and functional validation of bio-transformed selenium nanoparticles [0.03%]
绿色合成、表征及生物转化硒纳米粒子的功能验证
S Vasanthakumar,M Manikandan,Muthu Arumugam
S Vasanthakumar
Selenium, an essential micronutrient with potent anticancer and antioxidant properties, the inorganic form of selenium is highly toxic, while organic and elemental nanoforms are more bioavailable and less toxic and have gained attention owi...
Harnessing systems biology approach for characterization of carotenoid biosynthesis pathways in microalgae [0.03%]
利用系统生物学方法研究微藻类胡萝卜素生物合成途径
Bahman Panahi,Nahid Hosseinzadeh Gharajeh,Hossein Mohammadzadeh Jalaly et al.
Bahman Panahi et al.
Systems biology is an interdisciplinary field that aims to understand complex biological processes at the system level. The data, driven by high-throughput omics technologies, can be used to study the underpinning mechanisms of metabolite p...