Spray-Printed UiO-66/Polyaniline Composite Films: Tuning MOF Content and Conductivity for Enhanced Ammonia Detection [0.03%]
喷涂UiO-66/聚苯胺复合膜：调节金属有机骨架含量和电导率以增强氨气检测性能
Tzer-Rurng Su,Derrick Vong,Lillian Weiss et al.
Tzer-Rurng Su et al.
Low-concentration ammonia detection is critical for applications in environmental monitoring, agricultural production, and occupational health protection. To enhance the material's gas-detection capability, a nanocomposite of a MOF and a co...
Light-Triggered p-n Junction Switching in Hierarchical GaxIn2-xO3@MIL-68(GaIn) Nanotube Gas Sensors with Thermally Adaptive Dual-Selectivity toward Acetic Anhydride and Isopropanol [0.03%]
光触发的分层GaₓIn₂₋ₓO₃@MIL-68(GaIn)纳米管气敏半导体中的P-N结转换及对冰醋酸和异丙醇的热响应双重选择性研究
Wangyang Wu,Rui Zhang,Hongmin Zhu et al.
Wangyang Wu et al.
Acetic anhydride and isopropanol are essential chemical raw materials, and their accurate and efficient detection is of great significance. Conventionally, the sensing of these two gases requires two distinct types of sensors, which increas...
Yuxi Ma,Yi Deng,Jiaying Xu et al.
Yuxi Ma et al.
CRISPR-based molecular diagnostics have emerged as powerful and programmable platforms that enable sensitive and specific detection for disease management and epidemiological surveillance. Advances in CRISPR engineering and assay design are...
Kinetic-Gated Signal Transduction Decouples Binding Affinity in a Dual-Pocket Riboswitch RNA [0.03%]
动力学门控信号转导脱钩双袋核糖开关RNA中的结合亲和力
Dian Chen,Yu Liu
Dian Chen
RNA has emerged beyond its traditional biological role to become a premier biorecognition element in biosensor design. While single-target RNA sensors demonstrate high specificity, multi-pocket variants, such as the tetrahydrofolate (THF) r...
Electrochemical Cytosensor with Dual-Site Recognition Fabricated by In Situ Catalase-Encapsulated Metal-Organic Frameworks for Isolation and Detection of Circulating Tumor Cells in Whole Blood [0.03%]
一种新型电化学细胞传感器，利用原位封装辣根过氧化物酶的金属有机骨架材料进行循环肿瘤细胞的捕获及检测
Na Gan,Peiran Liu,Tingting Zeng et al.
Na Gan et al.
Circulating tumor cells (CTCs) are critical biomarkers for cancer prognosis and treatment monitoring, yet their detection remains challenging due to low abundance and phenotypic heterogeneity. Herein, we developed a dual-aptamer-conjugated ...
Adaptive Electrochemical Aptamer Sensing across Biofluid-Relevant pH Ranges via a Dual-Stage Machine Learning Framework [0.03%]
一种基于双阶段机器学习框架的自适应电化学适配子传感器技术，在生物液体相关pH范围内进行检测和传感
Wenjun He,Jihong Sun,Mark Leach et al.
Wenjun He et al.
Reliable electrochemical sensing can be hindered by environmental variability such as pH fluctuations, ionic strength, and nonspecific adsorption, which compromise signal fidelity and quantitative accuracy. Here, we present a dual-stage mac...
FOCUS: A Dual-Mismatch crRNA Strategy Unlocks High-Fidelity One-Step SNV Detection with Cas12a [0.03%]
聚焦：一种双错配crRNA策略可利用Cas12a实现一步精准单碱基突变检测
Miaojin Zhou,Kun Du,Mingjun Jiang et al.
Miaojin Zhou et al.
CRISPR/Cas12a has emerged as a powerful tool for nucleic acid detection; however, its clinical utility is severely hampered by intrinsic limitations in single-nucleotide variant (SNV) discrimination, reliance on pre-processed single-strande...
Full-Range Ultrasensitive Fiber-Optic Hydrogen Detection via Twin Vernier Amplification and Lightweight CNN [0.03%]
基于双V型腔放大和轻量级卷积神经网络的全量程高灵敏度光纤氢气传感技术
Chaofan Li,Yinuo Yan,Lufeng Wang et al.
Chaofan Li et al.
Reliable hydrogen monitoring requires sensors that combine high sensitivity, wide dynamic range, and resistance to environmental interference. Here, we report a monolithically integrated dual-Fabry-Pérot interferometer (dual-FPI) fiber-opt...
High-Throughput and Direct Microplastic Analysis via Flow Raman Spectroscopy [0.03%]
基于流动拉曼光谱的微塑料高通量直接分析法研究
Alexander Kissel,Christian Blum,Florian Hausladen et al.
Alexander Kissel et al.
Raman spectroscopy has become a widely applied and powerful analytical tool across numerous scientific disciplines due to its ability to provide detailed molecular information in a non-destructive manner. In environmental sciences, it is pa...
Radical Shielding Suppresses False Positives in Self-Powered Microfluidic Sensors [0.03%]
屏蔽效应减少自供电微流控传感器假阳性检测
Yetong Ji,Xue Bai,Ma Bai et al.
Yetong Ji et al.
Fuel cell-driven self-powered sensors facilitate continuous environmental analysis, but they frequently suffer from false-positive signals caused by coexisting interfering species. Herein, a radical shielding strategy was developed by integ...