Qian Gong,Linfang He,Fan Huang et al.
Qian Gong et al.
Light undergoes dramatic spectral shifts at dusk (sunset) and dawn (sunrise), enhancing insect activity and increasing the risk of insect-borne virus transmission. However, how plants respond to these light changes and associated viral thre...
Deep Arctic Ocean warming enhanced by heat transferred from deep Atlantic [0.03%]
深入北极海洋的暖流加剧了来自大西洋深处的热量传输导致的北极海洋变暖
Ruizhe Song,Xianyao Chen,Hanwen Bi et al.
Ruizhe Song et al.
Observations since the 1990s reveal widespread warming in the deep and bottom Arctic Ocean. It is historically attributed to geothermal heating, whereas the impacts of global and Arctic climate change on the deep and bottom Arctic Ocean war...
A synthesized framework for the evolutionary origins of avian obligate brood parasitism [0.03%]
关于鸟类强制寄生起源的合成框架
Nan Lyu,Xiaoyuan Wu,Yang Zhang et al.
Nan Lyu et al.
The repeated evolution of avian obligate brood parasitism (OBP) across diverse lineages represents a major evolutionary puzzle. While host-parasite coevolution has been extensively studied, the initial conditions favoring OBP emergence rema...
Dieke Gerritsen,Stuart A Gilder,Yi-Wei Chen et al.
Dieke Gerritsen et al.
The rise of the Yellowstone plume coincided with a shift from orogenic collapse of the Cordillera to Basin and Range extension in the northern Rocky Mountains, yet its impact on regional uplift, sediment dispersal, and drainage patterns rem...
AI-driven discovery of dual antiaging and anti-AD therapeutics via PROTAC target deconvolution of a super-enhancer-regulated axis [0.03%]
基于增强子调控轴的分子机制解析驱动的双重抗衰老和治疗阿尔兹海默症药物研发
Yuan Sun,Sai Liu,Long Chen et al.
Yuan Sun et al.
The lack of safe, durable therapeutics that act against both biological aging and Alzheimer's disease is an unmet clinical need. To bridge this gap, we devised an artificial intelligence (AI)-enabled approach that pairs rapid compound triag...
Porcine airway tissue explant culture at a hydrogel-air interface to model submucosal glands in cystic fibrosis progression and therapy [0.03%]
用于囊性纤维化进展和治疗的小鼠气道组织芯片模型中亚粘膜腺的研究
Kaleb C Bierstedt,Meng-Hsuan Lin,Wenjie Yu et al.
Kaleb C Bierstedt et al.
Submucosal glands (SMGs) are critical for airway health; however, replicating their complex structure and function outside the body remains challenging. Here, we establish a method of airway tissue explant culture at a hydrogel-air interfac...
Nanofluidic-engineered carbon nanotube ion highways in hydrogels enable high-power aqueous zinc-ion batteries [0.03%]
水凝胶中的纳米流体工程碳纳米管离子高速公路实现高性能水电锌离子电池
Dewu Lin,Jiapei Li,Mingzhan Wang et al.
Dewu Lin et al.
Quasi-solid polymer electrolytes (QSPEs) for flexible batteries face critical limitations in ion transport efficiency at high currents. We address this with a design of nanofluidic polyacrylamide hydrogel integrating aligned single-walled c...
ENSO's changing grip on Bering Sea ice: The emerging control of the North Pacific meridional mode [0.03%]
变暖背景下海洋-atmosphere系统变化对白令海冰影响的研究：北太平洋南北振荡的作用
Jiepeng Chen,Jin-Yi Yu,Chunzai Wang et al.
Jiepeng Chen et al.
Bering Sea winter sea ice (BSWI), vital for regional climate, ecosystem, and livelihoods, is significantly influenced by El Niño-Southern Oscillation (ENSO). Here, we identify a shift in the ENSO-BSWI relationship. Pre-mid-1990s, tradition...
Liang Liu,Jason P Morgan,Yi-Gang Xu et al.
Liang Liu et al.
Hotspot swells have typically been associated with mantle plume upwelling, yet the origins of much broader but lower superswells remain unclear. This study first reveals that swell width increases while height decreases at younger seafloor ...
Serine tRNAs compete to regulate the mRNA translation of serine-sensitive codons [0.03%]
丝氨酸tRNA竞争调控丝氨酸敏感密码子的翻译
Veronica Costiniti,Wyatt C Tran,Nandhini Rajesh Babu et al.
Veronica Costiniti et al.
Differential mRNA translation efficiency (mTE) of codons is important in regulating protein synthesis and cellular states and can change in response to amino acid availability. While the mTE of codons is canonically associated with their co...