Entropic-dielectric interplay governs ion adsorption in inner electric double layers [0.03%]
熵-介电相互作用支配内电双层中的离子吸附现象
Matteo Olgiati,Florian Altmann,Moritz Zelenka et al.
Matteo Olgiati et al.
Ion-specific effects at aqueous interfaces are fundamental to chemistry, biology, and environmental science, yet unraveling their thermodynamic origins remains challenging. Here, we quantitatively resolve interfacial thermodynamics at molec...
Intestinal resident effector-memory CD4 T cells on the adaptive-innate spectrum comprise IL-18 reactivity and adaptive CMV specificity [0.03%]
具有适应性CMV特异性的适应性/固有光谱上的肠驻留效应记忆CD4 T细胞包含IL-18反应性
Tobias Kammann,Isabel Voigt,Nicole Wild et al.
Tobias Kammann et al.
The human tissue-resident T cell pool consists of a diverse array of conventional adaptive as well as unconventional invariant T cells that populate barrier sites and carefully balance immune defense in the context of microbial exposure. He...
Solar-mechanical H2O2 production powered by defect dipole polarization in a nonpolar semiconductor [0.03%]
非极性半导体中缺陷偶极子极化驱动的太阳能机械式过氧化氢生产
Cheng Chen,Junjie Ni,Peifang Wang et al.
Cheng Chen et al.
Piezo-photocatalytic H2O2 production faces a central challenge: inadequate visible-light absorption and insufficient driving forces for charge separation, especially in wide-bandgap nonpolar semiconductors. To address this, we propose a str...
Haotian Chen,Yujun Chen,Yingying Wang et al.
Haotian Chen et al.
Autonomous microrobots can reach hard-to-access regions in the human body for minimally invasive therapy. However, their microscale size limits the integration of on-board memory, making their operation dependent on external controls. Here,...
A Wnt-induced conformational phospho-switch in DVL3 controls association with Frizzled receptors and Wnt/β-catenin signaling [0.03%]
DVL3通过Wnt诱导的构象磷酸化转换控制与Frizzled受体结合和Wnt/β-联蛋白信号转导
Miroslav Micka,Jitender Kumar,Petra Paclíková et al.
Miroslav Micka et al.
It is well known that Dishevelled (DVL) phosphorylation by casein kinase 1 (CK1) relays Wnt signals from Frizzled (FZD) receptors to downstream effectors, yet any mechanistic aspects of DVL function related to phosphorylation remain unresol...
David Anthony,Martin Trautmann,Volker Heyd
David Anthony
Recent papers argued that the domestication of horses can be equated with the appearance of favorable genetic mutations that are first evident in individuals in the DOM2 clade dated about ∼2200-2100 BCE. We challenge the idea that this gen...
Beyond seizure control: Identifying deficits in cognitive networks in absence epilepsy [0.03%]
揭秘失神癫痫:认知网络缺陷超越了发作控制
Gil Vantomme,Gabrielle Devienne,Jacob M Hull et al.
Gil Vantomme et al.
Cognitive impairments are common in absence epilepsy, yet the neural basis of these deficits remains largely unknown. Communication between the thalamic reuniens nucleus and the prefrontal cortex is critical for flexible behavior. Here, we ...
Polyketide synthase-like functionality acquired by plant fatty acid elongase [0.03%]
植物脂肪酸延伸酶获得类似聚酮合酶的功能性
Hyojin Kim,Kiyoul Park,Hao Jia et al.
Hyojin Kim et al.
Fatty acid elongation typically proceeds through a four-step cycle of condensation, reduction, dehydration, and reduction for each two-carbon extension. Here, we describe a variation of this pathway in Orychophragmus limprichtianus, whose s...
Wind stilling shapes grassland water use efficiency by enhancing soil moisture retention [0.03%]
风的抑制通过增强土壤保水能力来影响草地水分利用效率
Haohao Wu,Congsheng Fu,Philippe Ciais et al.
Haohao Wu et al.
Covering more than 40% of Earth's vegetated surface, grasslands critically regulate terrestrial carbon and water cycles. Their ecosystem water use efficiency (WUEeco), the ratio of carbon uptake to water loss, governs drought resilience in ...
Beyond formic acid: Peptides in carpenter ant venoms aid in disease protection [0.03%]
甲酸之外:白蚁毒液中的多肽有助于疾病防御
Lukas Koch,Sandro Andreotti,Mario Schubert et al.
Lukas Koch et al.
Venom peptides are key to the evolutionary success of most venomous animals, including stinging ants. The stingless ant subfamily Formicinae is thought to rely solely on formic acid in their venoms, despite early, unsubstantiated hints of p...