The Antarctic coastal ocean heat budget is dominated by heat loss to land ice melt [0.03%]
南极沿海海洋热收支受制于冰川融化致海水热量损失主导格局
Ruth Moorman,Andrew F Thompson,Madeleine K Youngs et al.
Ruth Moorman et al.
Transport of warm Circumpolar Deep Water (CDW) across the Antarctic continental shelf break is the primary source of heat to Antarctica's marginal seas. Net heat supplied by CDW is ultimately lost to: (i) the ocean surface, either to the at...
Causal parametric language mapping with electrical stimulation during awake neurosurgery [0.03%]
觉醒神经外科电刺激下的因果参数语言定位mapping
J Raouf Belkhir,Frank E Garcea,Eduardo Navarrete et al.
J Raouf Belkhir et al.
Functional mapping with direct electrical stimulation (DES) is widely used during awake neurosurgery to generate causal evidence about person-specific neuroanatomical organization. According to a long-standing clinical and scientific paradi...
Enteric botulinum neurotoxins facilitate infection by Salmonella and Shigella [0.03%]
肉毒杆菌神经毒素可促进沙门氏菌和志贺氏菌感染肠道神经系统
Federico Fabris,Paola Brun,Aram Megighian et al.
Federico Fabris et al.
Botulism is a life-threatening disease caused by botulinum neurotoxins (BoNTs) released by Clostridium bacteria. BoNTs induce a flaccid paralysis by blocking neurotransmitter release from peripheral cholinergic neurons via soluble N-ethylma...
Seung-Rok Kim,Noelle Davis,Kalynna Tang et al.
Seung-Rok Kim et al.
CO2 is a key physiological parameter used to assess hypoventilation and to estimate metabolic rates. However, current CO2 monitoring relies on bulky breath-analysis systems that are impractical for continuous use in daily life. Here, we pre...
Spatiotemporal Raman probing of molecular transport in sub-2-nm plasmonic quasi-2D nanochannels [0.03%]
亚2 nm等离子体准二维纳米通道中分子输运的时空拉曼探测
Haoran Liu,Zihe Jiang,Zhiwei Hu et al.
Haoran Liu et al.
Capturing molecular dynamics in nanoconfined channels with high spatiotemporal resolution is a key challenge in nanoscience, crucial for advancing catalysis, energy conversion, and molecular sensing. Bottom-up ultrathin plasmonic nanogaps, ...
Inflamed vessel-anchored release of H2 across the blood-brain barrier for ischemic stroke neuroprotection [0.03%]
炎症血管定位释放H₂通过血脑屏障治疗缺血性卒中的神经保护作用
Yuanman Yu,Mingjian Fan,Gaoyi Wu et al.
Yuanman Yu et al.
Ischemic stroke followed by reperfusion urgently requires safe and efficient cytoprotective strategies, a need still unmet by current pharmacotherapies. Nanotechnology holds promise for improved drug delivery to the brain, yet the efficacy ...
Feng Nan,Huijie Xue,Fei Yu et al.
Feng Nan et al.
The South China Sea throughflow (SCSTF) serves as a heat and freshwater conveyor, playing a pivotal role in regulating physical processes and biogeochemical cycles in the SCS. Because of limited observations, the long-term changes of the SC...
Accretion of volatile elements on Earth without the need of a late veneer [0.03%]
地球挥发元素的积累无需晚期 veneer 的存在
Lucas Calvo,Julien Siebert,Dongyang Huang et al.
Lucas Calvo et al.
Volatile elements are essential for life development and planetary evolution. However, the timing of their delivery to terrestrial planets remains unclear. Sulfur, selenium, and tellurium are volatiles, but also siderophile elements. Their ...
Diverse database and machine learning model to narrow the generalization gap in RNA structure prediction [0.03%]
用于缩小RNA结构预测泛化间隙的多样数据库和机器学习模型
Albéric A de Lajarte,Yves J Martin des Taillades,Justin Aruda et al.
Albéric A de Lajarte et al.
Understanding macromolecular structures of proteins and nucleic acids is critical for discerning their functions and biological roles. Advanced techniques-crystallography, nuclear magnetic resonance, and cryo-electron microscopy-have facili...
The thermodynamic opportunities hypothesis: Metabolic temperature insensitivity across flatfish species [0.03%]
变温条件下rays的代谢温度 insensitive性：机会假说视角
Brad A Seibel
Brad A Seibel
This study challenges widely held metabolic theory, which suggests that whole-animal metabolic rates increase with temperature because of its universal effects on the kinetics of the underlying biochemical reactions. Here, we show that meta...