Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity [0.03%]
沙门氏菌致病性的中央调节因子的合成小分子抑制剂的发现
Abdelhakim Boudrioua,Joe D Joiner,Iwan Grin et al.
Abdelhakim Boudrioua et al.
The enteric pathogen Salmonella enterica serovar Typhimurium relies on the activity of effector proteins to invade, replicate, and disseminate into host epithelial cells and other tissues, thereby causing disease. Secretion and injection of...
Evidence for crustal brines and deep fluid infiltration in an oceanic transform fault [0.03%]
板块转换断层地壳卤水及深部流体渗入的证据
Christine Chesley,Rob Evans,Jessica M Warren et al.
Christine Chesley et al.
Although oceanic transform faults (OTFs) are ubiquitous plate boundaries, the geological processes occurring along these systems remain underexplored. The Gofar OTF of the East Pacific Rise has gained attention due to its predictable, yet e...
Mariana Tinajero-Trejo,Matthew Aindow,Laia Pasquina-Lemonche et al.
Mariana Tinajero-Trejo et al.
Bacterial cell division is a complex, multistage process requiring septum development while maintaining cell wall integrity. A dynamic, macromolecular protein complex, the divisome, tightly controls morphogenesis both spatially and temporal...
On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs [0.03%]
代谢产物数量性状位点的分析：不同数据转换和研究设计的影响
Sanghun Lee,Rachel S Kelly,Kevin M Mendez et al.
Sanghun Lee et al.
Metabolomic genome-wide association studies (mGWASs), or metabolomic quantitative trait locus (metQTL) analyses, are gaining growing attention. However, robust methods and analysis guidelines, vital to address the complexity of metabolomic ...
Sophia N Fricke,Mia Salgado,Shira Haber et al.
Sophia N Fricke et al.
Chemical recycling of commodity and specialty polymers presents a multifaceted challenge for industrial societies. On one hand, macromolecular architectures must be engineered to yield durable products that, on the other hand, rapidly decon...
Make it flow from solid to liquid: Redox-active electrofluids for intrinsically stretchable batteries [0.03%]
从固态到液态流动的氧化还原活性电控流体用于本征可拉伸电池
Mohsen Mohammadi,Saeed Mardi,Jaywant Phopase et al.
Mohsen Mohammadi et al.
High-capacity stretchable batteries are crucial for next-generation wearables to enable long-term operation and mechanical conformability with the human user. In existing stretchable battery designs, increasing the active material to yield ...
Natural variation in a cortex/epidermis-specific transcription factor bZIP89 determines lateral root development and drought resilience in maize [0.03%]
玉米皮层/表皮特异性转录因子bZIP89的自然变异决定侧根发育和抗旱性
Pengcheng Li,Tianze Zhu,Yunyun Wang et al.
Pengcheng Li et al.
Lateral roots (LRs) branching is crucial for water and nutrient acquisition in plants, ultimately determining the overall plant performance and productivity. However, the transcriptional regulation of LR development in crops and its role in...
Distinct transmission sites within a synapse for strengthening and homeostasis [0.03%]
突触中用于增强和稳态的不同的传递位点
Yue Yang,Man Ho Wong,Xiaojie Huang et al.
Yue Yang et al.
At synapses, miniature synaptic transmission forms the basic unit of evoked transmission, thought to use one canonical transmission site. Two general types of synaptic plasticity, associative plasticity to change synaptic weights and homeos...
Rotatum of light [0.03%]
光的旋轮变换
Ahmed H Dorrah,Alfonso Palmieri,Lisa Li et al.
Ahmed H Dorrah et al.
Vortices are ubiquitous in nature and can be observed in fluids, condensed matter, and even in the formation of galaxies. Light, too, can evolve like a vortex. Optical vortex beams are exploited in light-matter interaction, free space commu...
Petrologic evidence for core sulfur degassing in partially differentiated planetesimals [0.03%]
部分分化的行星esimal硫脱气的岩石学证据
Shu-Zhou Wang,Ai-Cheng Zhang,Tian-Ran Trina Du et al.
Shu-Zhou Wang et al.
Partial differentiation hypothesis is a scenario for interpreting the internal structure of planetesimals and the genetic relationship between chondrites and nonchondrites. However, no petrologic records supporting this hypothesis have been...