On the role of α-alumina in the origin of life: Surface-driven assembly of amino acids [0.03%]
α-氧化铝在生命起源中的作用:氨基酸的表面驱动组装
Ruiyu Wang,Richard C Remsing,Michael L Klein et al.
Ruiyu Wang et al.
We investigate the hypothesis that mineral/water interfaces played a crucial catalytic role in peptide formation by promoting the self-assembly of amino acids. Using classical molecular dynamics simulations, we demonstrate that the α-alumi...
Histone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in Saccharomyces cerevisiae [0.03%]
酿酒酵母中组蛋白H3的半胱氨酸110增强铁代谢并调节复制寿命
Chen Cheng,Brenna S McCauley,Nedas Matulionis et al.
Chen Cheng et al.
The discovery of histone H3 copper reductase activity provides a novel metabolic framework for understanding the functions of core histone residues, which, unlike N-terminal residues, have remained largely unexplored. We previously demonstr...
Confirmation of Breslow's hypothesis: A carbene stable in liquid water [0.03%]
布雷尔伍德假说的验证——一种在液态水中稳定的卡宾
Varun Tej Raviprolu,Aaron Gregory,Isaac Banda et al.
Varun Tej Raviprolu et al.
In 1958, Breslow proposed that the coenzyme thiamine, also known as vitamin B1, acted as a source of transient carbenes that facilitated the catalytic activity of various important enzymes. This was a controversial hypothesis, as, then and ...
The cohesin-associated protein Pds5A governs the meiotic spindle assembly via deubiquitination of Kif5B in oocytes [0.03%]
卵母细胞中的Pds5A通过去泛素化Kif5B调控姊妹染色单体粘连及同源重组修复以维持减数分裂纺锤体的正常组装
Yu Zhang,Jie Bai,Bo Xiong
Yu Zhang
Chromosome cohesion mediated by cohesin complex and its associated proteins is required for accurate chromosome segregation and genomic stability in mitosis. However, because of the distinct operation mechanisms, many proteins might exert d...
The origin of sound damping in amorphous solids: Defects and beyond [0.03%]
非晶固体声学阻尼的起源:缺陷及其以外的因素的影响
Elijah Flenner,Grzegorz Szamel
Elijah Flenner
Comprehending sound damping is integral to understanding the anomalous low temperature properties of glasses. After decades of studies, Rayleigh scaling of the sound attenuation coefficient with frequency, [Formula: see text], became genera...
Science-based suggestions to save the world's rarest primate species Nomascus hainanus [0.03%]
关于拯救世界最濒危灵长类动物海南长臂猿的科学建议
Xukai Zhong,Xia Huang,Changyue Zhu et al.
Xukai Zhong et al.
Conservation practices for extremely small populations must be grounded in solid science to prevent extinction. Hainan gibbon (Nomascus hainanus) is the world's rarest primate species; however, insufficient data on its habitat suitability a...
A dual-mechanism luminescent antibiotic for bacterial infection identification and eradication [0.03%]
一种用于细菌感染识别和消除的发光抗生素的双机制研究
Guobin Qi,Xianglong Liu,Hao Li et al.
Guobin Qi et al.
Because of the rapid emergence of antibiotic-resistant bacteria, there is a growing need to discover antibacterial agents. Here, we design and synthesize a compound of TPA2PyBu that kills both Gram-negative and Gram-positive bacteria with a...
Radiative cooling induced coherent maser emission in relativistic plasmas [0.03%]
相对论性等离子体中辐射冷却引起的相干受激辐射放大效应
Pablo Bilbao,Thales Silva,Luís O Silva
Pablo Bilbao
Relativistic plasmas in strong electromagnetic fields exhibit distinct properties compared to classical plasmas. In astrophysical environments, such as neutron stars, white dwarfs, active galactic nuclei, and shocks, relativistic plasmas ar...
Emily C Geyman,Yutian Ke,John S Magyar et al.
Emily C Geyman et al.
Nearly 10% of Earth's continents are covered by river floodplains. These landscapes serve as weathering reactors whereby particles eroded from mountains undergo chemical and physical alteration before being exported to oceans. The time a pa...
Decoding the interstitial/vacancy nature of dislocation loops with their morphological fingerprints in face-centered cubic structure [0.03%]
面心立方结构中利用位错环的形态指纹解码其空位/间隙本质
Kan Ma,Long Guo,Antoine Dartois et al.
Kan Ma et al.
Dislocation loops are critical defects inducing detrimental effects like embrittlement and swelling in materials under irradiation. Distinguishing their nature (interstitial- or vacancy-type) is a long-standing challenge with great implicat...