Milan Becker,Nimrod Leberstein,Mark Shein-Idelson
Milan Becker
A multilayered, thalamorecipient visual cortex emerged ~320 million years ago in stem amniotes. Despite its importance for understanding the evolution of cortical computation, its function remains unknown. We recorded visually evoked respon...
TOP2B modulates DNA supercoiling and chromatin contacts during transcriptional induction [0.03%]
转录激活过程中，TOP2B调节DNA超螺旋和染色质相互作用
José Terrón-Bautista,Marina Bejarano-Franco,María Del Mar Martínez-Sánchez et al.
José Terrón-Bautista et al.
Human type-II topoisomerases, TOP2A and TOP2B, resolve transcription-associated DNA supercoiling, thereby influencing gene expression programs, and have been recently linked to three-dimensional genome architecture through yet poorly unders...
Spatiotemporally programmed dielectric liquid crystal elastomer: Electro-reversible 3D morphing via inverse 4D printing [0.03%]
时空编程介电液晶弹性体：通过逆四维打印实现可逆三维形变
Huiyao Zhao,Zike Chen,Jiahao Li et al.
Huiyao Zhao et al.
Programmable shape-morphing materials offer transformative potential in soft robotics and biomedical engineering, yet achieving reversible and precise control over complex 3D deformations remains a notable challenge due to the difficulty in...
Societal restraint of behavior during the pre-vaccine pandemic saved working-age men but not women [0.03%]
社会约束在疫苗问世前的疫情期间有效限制了劳动年龄男性的行为但对女性无效
Ralph Catalano
Ralph Catalano
Risky behavior disproportionately contributes to death in the working-age (i.e., 15 to 64 years old) population. Men exhibit riskier behavior than do women. As a result, working-age men die more frequently than do working-age women. Despite...
Quanyin Xu,Zhenghao Wu,Katelyn Randazzo et al.
Quanyin Xu et al.
Among glasses, polymers stand out as the chain connectivity endows them with distinct properties in glass formation, among them the transition temperature (Tg) and dynamic fragility (m) varying with chain length. Here, we resolve the nature...
A three-dimensional photoacoustic and ultrasound automated breast volume scanner (PAUS-ABVS) for breast cancer patients [0.03%]
用于乳腺癌患者的三维光声和超声自动乳房体积扫描仪(PAUS-ABVS)
Sinyoung Park,Minsik Sung,Hyunhee Kim et al.
Sinyoung Park et al.
Breast cancer screening with mammography is less effective in women with dense breast tissue, prompting the use of ultrasound (US) imaging. While two- (2D) and three-dimensional (3D) US improve cancer detection, their low specificity leads ...
Halina B Stanley,Clémentine Lipp,Coralie Mignot et al.
Halina B Stanley et al.
Smell loss is a sensory impairment that has major consequences in many areas of daily life and for which current therapies are insufficient. A prosthesis-type technology enabling patients to sample their olfactory environment has not yet be...
Animal tracking with particle algorithms informs protected area design [0.03%]
基于粒子算法的动物追踪对保护区的设计具有指导意义
Edward Lavender,Andreas Scheidegger,Carlo Albert et al.
Edward Lavender et al.
Animal movements affect their exposure to threats and the efficacy of conservation measures, such as marine protected areas (MPAs). However, many species' movements are difficult to reconstruct from available datasets, hampering conservatio...
Mapping the chronology of an ancient cosmovision: 4000 years of continuity in Pecos River style mural painting and symbolism [0.03%]
绘制古代宇宙视野的时间脉络：佩科斯河岩画风格4000年的传承与发展
Karen L Steelman,Carolyn E Boyd,J Phil Dering
Karen L Steelman
Forager societies in southwest Texas and northern Mexico painted polychromatic Pecos River style murals in limestone rock shelters containing well-preserved archaeological assemblages. To establish the temporal context of the murals, we obt...
Widespread association of Polycomb complex-deposited histone H2A monoubiquitylation with enhancers and neuronal gene regulation [0.03%]
多梳复合物沉积的组蛋白H2A单泛素化与增强子和神经元基因调控的广泛关联性分析
Kailynn MacGillivray,Daniel Fusca,Luomeng Tan et al.
Kailynn MacGillivray et al.
Disruption of histone H2A monoubiquitylation (H2AK119ub) causes neurodevelopmental disorders through poorly understood mechanisms. Polycomb complex-deposited H2AK119ub and trimethylation of histone H3 at lysine 27 (H3K27me3) can cooperative...