Circulation and ocean-ice shelf interaction beneath the Denman and Shackleton Ice Shelves [0.03%]
丹曼冰架和沙克尔顿冰架下的海洋环流及海冰相互作用
Stephen R Rintoul,Esmee M van Wijk,Laura Herraiz-Borreguero et al.
Stephen R Rintoul et al.
Ocean-driven basal melt can thin and weaken ice shelves, reducing buttressing and causing sea level rise. However, the processes driving melt in ice shelf cavities are challenging to observe. Here we report float observations spanning the o...
Mitochondria-localized photocatalyst of biomimetic organic semiconductor nanoparticles for NIR-activatable photocatalytic immunotherapy [0.03%]
用于近红外激活的光催化免疫治疗的线粒体定位仿生有机半导体纳米光催化剂
Yu Wang,Yijian Gao,Yuliang Yang et al.
Yu Wang et al.
Photocatalytic therapy holds great prospects in high-performance tumor treatment owing to its advantages of noninvasiveness and oxygen nonreliance. However, there is still a lack of ideal photocatalyst materials that respond to near-infrare...
Taichiro Fukui,Kei Sumita,Hiroki Miyano et al.
Taichiro Fukui et al.
High-speed active metasurfaces enable spatiotemporal light control within an ultrathin device layer, offering previously unexplored possibilities for optical communication, sensing, and computing. However, a trade-off between electrical con...
Shifting cyclone travel speed and its impact on global mangrove ecosystems [0.03%]
cyclone行进速度的变化及其对全球红树林生态系统的影响
Yu Mo,Jim W Hall,Andrew H Baldwin et al.
Yu Mo et al.
Cyclones cause major damage to mangrove ecosystems globally. While this damage is projected to increase as storms intensify with climate change, the consequences of changes in cyclone attributes other than wind speed remain largely unexplor...
The past and future of known biodiversity: Rates, patterns, and projections of new species over time [0.03%]
已知生物多样性的过去与未来：新物种发现的速度、模式和预测
Xin Li,Ding Yang,Liang Wang et al.
Xin Li et al.
Our understanding of biodiversity patterns comes primarily from described species. Here, we analyze how known biodiversity has increased across living organisms. Past research suggested that the number of new species per year peaked near 19...
High-entropy perovskite oxides: Morphotropic phase boundary interfacial engineering for next-generation communications [0.03%]
高熵钙钛矿氧化物：用于下一代通信的相界界面工程
Kai Yao,Lixin Song,Xiang Zhang et al.
Kai Yao et al.
Precise atomic-level control over interfacial charge density and lattice distortions remains a critical challenge across electromagnetism, optoelectronics, and catalysis. Here, we introduce a high-entropy strategy that leverages local compo...
Atom-level machine learning of protein-glycan interactions and cross-chiral recognition in glycobiology [0.03%]
基于原子水平的蛋白质-糖链相互作用及糖生物学中交叉手性识别的机器学习研究
Eric J Carpenter,Chuanhao Peng,Simatsidk Haregu et al.
Eric J Carpenter et al.
We describe a machine-learned (ML) model, MCNet, which predicts interactions between proteins and glycans. MCNet predicted quantitative interactions between glycan-binding proteins (GBPs) and enantiomers of common glycans, which were not pa...
Multidimensional dynamic optical imaging unveils anesthetic-driven hemispheric lateralization in blood-brain barrier homeostasis [0.03%]
多维动态光学成像揭示麻醉剂驱动的血脑屏障稳态半球侧化现象
Honghui Li,Mingyang Sun,Bowen Zhu et al.
Honghui Li et al.
The blood-brain barrier (BBB) is commonly known to be distributed evenly within the central nervous system. This study elucidates previously unexplored physiological phenomena associated with the spatial heterogeneity of the BBB. We found t...
Investigating charge accumulation mechanisms in organic materials via slow transient emission spectroscopy [0.03%]
利用慢瞬态发射光谱研究有机材料中的电荷累积机制
Ryoko Oyama,Kaede Kawaguchi,Liliia Moshniaha et al.
Ryoko Oyama et al.
Long-persistent luminescent (LPL) materials store photon energy as charges and emit light over extended periods via charge recombination. LPL decay typically follows a power law rather than an exponential decay, enabling confirmation of cha...
Tumor microenvironment-targeted PROTAC nanoparticle self-assembly broadly predicted by structural descriptors [0.03%]
基于结构描述符的肿瘤微环境靶向PROTAC纳米颗粒自组装广泛预测
Kristen C Vogt,Magdalini Panagiotakopoulou,Mandana T Manzari Honu et al.
Kristen C Vogt et al.
Proteolysis-targeting chimeras (PROTACs) are catalytic protein degraders with promising preclinical activity. The clinical translation of PROTACs has been limited by poor pharmacologic properties and toxicities, in part due to their "non-dr...