Heng Ma,Longsheng Jiang,Tao Liu et al.
Heng Ma et al.
Classification constitutes a fundamental cognitive challenge for both biological and artificial intelligence systems. Here, we investigated how the brain categorizes stimuli that are not linearly separable in the physical world by analyzing...
Reconstructing Eocene Antarctic river drainage from provenance analysis of Amundsen Sea embayment sediments [0.03%]
基于泛安德丝海沉积物汇水区分析重建的渐新世南极河流集水系统
James W Marschalek,Tina van de Flierdt,Christine S Siddoway et al.
James W Marschalek et al.
Sedimentary records can illuminate relationships between the climate, topography, and glaciation of West Antarctica by revealing its Cenozoic topographic and paleoenvironmental history. Eocene fluvial drainage patterns have previously been ...
Dana Darmohray,Jiao Sima,Chien-Hao Chen et al.
Dana Darmohray et al.
Increased sleep induced by immune activation plays a crucial role in facilitating recovery from illness. However, the neural mechanisms underlying sickness-induced sleep remain poorly understood. Here, we identify a brainstem circuit origin...
Fluidic microgel assemblies with enhanced oral delivery of biologics alleviate colonic inflammation in murine and canine models [0.03%]
一种基于微凝胶的递送系统，可通过口服途径有效治疗动物肠道炎症性疾病
Qingqiao Xie,Chenchen Yan,Zifeng Yang et al.
Qingqiao Xie et al.
The efficacy of oral delivery of biologic drugs for inflammatory bowel disease (IBD) treatment is substantially compromised by the swift enzymatic degradation and insufficient retention of biologics in the gastrointestinal tract. Here, we r...
Direct imaging of facet development during growth of single-crystal covalent organic frameworks [0.03%]
单晶共价有机框架生长过程中晶面发育的直接成像
Qianxi Wang,Quan Wu,Yi He
Qianxi Wang
Single-crystal covalent organic frameworks (COFs) have received increasing interest due to their well-defined structures and exceptional performance. However, the reaction pathways of the facet development during growth of single-crystal CO...
Scalable manufacturing of multifunctional insect wing membrane via interfacial lase-and-peel strategy [0.03%]
基于界面激光剥离策略的大规模多功能昆虫翼膜制造技术
Jing Bian,Yuxing Ma,Hong Ling et al.
Jing Bian et al.
Insect wings have unique, irregular nanopillars with multifaceted properties. One of the great challenges in broader applications of insect wing-inspired surfaces is to mass-produce insect-wing nanoarchitectures (IWNs) on ultrathin and dura...
Evolutionarily convergent mechanism of formin regulation coordinates actin polymerization in apicomplexan parasites [0.03%]
调控顶复门寄生虫肌动蛋白聚合的进化趋同调节机制
Pengge Qian,Yong Fu,Jianwei Zeng et al.
Pengge Qian et al.
Apicomplexan parasites rely on actin-based motility for host cell invasion and for their dissemination. Although previous studies implicate formin 1 (FRM1) in governing this process in Toxoplasma, the mechanisms that position it at the cell...
Immune control of functional memory CD8 T cells in normal-appearing vitiligo skin [0.03%]
正常外观的白癜风皮肤中的功能记忆CD8 T细胞的免疫调控
Laure Migayron,Ribal Merhi,Chloé Avril et al.
Laure Migayron et al.
Emerging evidence demonstrates that self-reactive CD8+ T resident memory cells (TRM cells) may already populate the never-lesional (NL) skin of patients with chronic inflammatory conditions, including vitiligo. However, their functional act...
Western North Pacific influences on the interannual to decadal variability of Barents-Kara Sea ice during spring [0.03%]
春季西太平洋的影响与巴伦支-喀拉海海冰年际至十年变异性的关联研究
Shutao Cao,Anmin Duan,Aiguo Dai et al.
Shutao Cao et al.
Spring sea ice cover in the Barents-Kara Seas (BKS) exhibits notable interannual to decadal variability with spatial patterns distinct from winter. While previous studies suggest that internal climate variability dominates, the specific dri...
Cosmic-ray bath in a past supernova gives birth to Earth-like planets [0.03%]
来自过去超新星的宇宙射线浴孕育地球 like 行星
Ryo Sawada,Hiroyuki Kurokawa,Yudai Suwa et al.
Ryo Sawada et al.
A key question in astronomy is how ubiquitous Earth-like rocky planets are. The formation of terrestrial planets in our Solar System was strongly influenced by the radioactive decay heat of short-lived radionuclides (SLRs), particularly 26A...