Tuning catalyst-support interactions enable steering of electrochemical CO2 reduction pathways [0.03%]
调控催化剂-载体相互作用可以控制电化学二氧化碳还原路径的选择性
Meng Wang,Yuke Li,Jinfeng Jia et al.
Meng Wang et al.
Tuning of catalyst-support interactions potentially offers a powerful means to control activity. However, rational design of the catalyst support is challenged by a lack of clear property-activity relationships. Here, we uncover how the ele...
Rapid sorting and auxiliary evaluation of malignant breast tumors by accurate imaging analysis of metastasis-related biomarker [0.03%]
基于转移相关生物标志物精准影像分析的乳腺恶性肿瘤快速甄别与辅助评估
Shan Zuo,Yanhua Li,Yushi Chen et al.
Shan Zuo et al.
Accurate differentiation of benign and malignant breast tumors is paramount for establishing schemes of breast cancer treatment and prognosis. Here we report a near-infrared (NIR) fluorescence probe (YF-1) with the overexpressed cathepsin C...
Siqi Yuan,Chenyu Pang,Liang Wu et al.
Siqi Yuan et al.
Atypical face processing is a neurocognitive basis of social deficits in autism spectrum disorder (ASD) and a candidate cognitive marker for the disease. Although hundreds of risk genes have been identified in ASD, it remains unclear whethe...
The inflammatory and genetic mechanisms underlying the cumulative effect of co-occurring pain conditions on depression [0.03%]
共病痛觉异常条件下抑郁症发生的炎症和遗传机制研究
Rongtao Jiang,Paul Geha,Matthew Rosenblatt et al.
Rongtao Jiang et al.
Chronic pain conditions frequently coexist and share common genetic vulnerabilities. Despite evidence showing associations between pain and depression, the additive effect of co-occurring pain conditions on depression risk and the underlyin...
A predatory gene drive for targeted control of self-transmissible plasmids [0.03%]
一种用于靶向控制自我传播质粒的捕食性基因驱动系统
Ryan Tsoi,Hye-In Son,Grayson S Hamrick et al.
Ryan Tsoi et al.
Suppressing plasmid transfer in microbial communities has profound implications due to the role of horizontal gene transfer (HGT) in spreading and maintaining diverse functional traits such as metabolic functions, virulence factors, and ant...
Microbial dipeptidyl peptidases of the S9B family as host-microbe isozymes [0.03%]
S9B家族微生物二肽基肽酶作为宿主-微生物异构酶
Mashael R Aljumaah,Jeffery Roach,Yunan Hu et al.
Mashael R Aljumaah et al.
Human dipeptidyl peptidase 4 (hDPP-4) has been a pharmacological target for metabolic diseases, particularly diabetes, since the early 2000s. As a ubiquitous enzyme found in both prokaryotic and eukaryotic organisms, hDPP-4 plays crucial ro...
Genomic insights into evolution of parthenogenesis and triploidy in the flowerpot snake [0.03%]
花盆蛇孤雌生殖和三倍体进化的基因组见解
Yunyun Lv,Wei Wu,Jin-Long Ren et al.
Yunyun Lv et al.
The flowerpot snake (Indotyphlops braminus) is the only known parthenogenetic and triploid species within Serpentes. However, the genetic basis underlying this phenomenon remains unresolved. We investigated the genomic complexities of this ...
Kaidong Liu,Yanrui Cui,Huiming Han et al.
Kaidong Liu et al.
Understanding the heterogeneity of fibroblasts depends on decoding the complexity of cell subtypes, their origin, distribution, and interactions with other cells. Here, we integrated 249,156 fibroblasts from 73 studies across 10 tissues to ...
Ligand spin immobilization in metal-organic frameworks enables high-performance chemispintronic detection of radical gas molecules [0.03%]
配体自旋固定在金属有机框架中可实现高性化学自旋电子学检测自由基气体分子
Cheng Liu,Xiao-Cheng Zhou,Guoao Li et al.
Cheng Liu et al.
The precise quantification of gaseous radicals in exhaled breath, such as fractional exhaled nitric oxide, serves as an invaluable noninvasive clinical diagnosis particularly in discerning various respiratory disorders. To date, the develop...
Neuroecology of alcohol risk and reward: Methanol boosts pheromones and courtship success in Drosophila melanogaster [0.03%]
酒精风险和回报的神经生态学：甲醇可增强黑腹果蝇的信息素和求偶成功性
Ian W Keesey,Georg Doll,Sudeshna Das Chakraborty et al.
Ian W Keesey et al.
Attraction of Drosophila melanogaster toward by-products of alcoholic fermentation, especially ethanol, has been extensively studied. Previous research has provided several interpretations of this attraction, including potential drug abuse,...