Best evidence summary for platelet-rich plasma treatment of chronic wounds [0.03%]
富血小板血浆治疗慢性难愈合创面的最佳证据总结
Xinru Zhang,Xingxing Zhang,Luxin Wang et al.
Xinru Zhang et al.
Objective: To summarize the best evidence for platelet-rich plasma therapy in chronic wounds, providing an evidence-based foundation for standardizing its clinical practice. ...
Wang Yuqiang,Zhang Ziyan,Sun Xuedi et al.
Wang Yuqiang et al.
Bone regeneration is a highly coordinated process shaped by the interplay between immune responses and osteogenic mechanisms. Immune cells such as neutrophils, macrophages, T cells, and B cells dynamically regulate the local microenvironmen...
Effect of local administration of microRNA-31/210 on bone regeneration surrounding hydroxyapatite/tricalcium phosphate -coated titanium implant in an ovariectomized rat model [0.03%]
微RNA-31/210局部作用通过卵巢切除大鼠模型评估其载有羟基磷灰石/三碳酸钙磷灰石涂层的钛种植体骨整合的影响
Shinichi Ueki,Takeshi Shoji,Hideki Saka et al.
Shinichi Ueki et al.
Background: With the aging population, the prevalence of total joint arthroplasty in older adults with compromised bone conditions, such as osteoporosis, is increasing, raising concerns on the initial fixation of implants...
Development of a digital analysis system for a novel 3D culture-based colony formation to detect malignantly transformed cells in human cell-based therapeutic products [0.03%]
人细胞治疗产品中恶性转化细胞检测的新型三维培养基 colony formation 数字分析系统开发
Shinji Kusakawa,Tingshu Yang,Rumi Sawada et al.
Shinji Kusakawa et al.
Introduction: The presence of malignantly transformed cells in human cell-based therapeutic products (hCTPs) is a significant safety concern. Although such cellular impurities in hCTPs can be assessed by detecting anchora...
NSUN2-engineered human umbilical cord mesenchymal stem cell-derived exosomes ameliorate tendon injury by promoting DNM2 expression [0.03%]
NSUN2工程人脐带间充质干细胞来源的外泌体通过促进DNM2表达修复肌腱损伤
Yuxin Liu,Yalu Pu,Qi Li et al.
Yuxin Liu et al.
Background: Tendon injuries are a common musculoskeletal problem, often leading to chronic pain and disability. Current treatment options, including surgical interventions and physical therapy, have limitations in terms o...
Lubricin maintains temporomandibular joint homeostasis by regulating synovial inflammation [0.03%]
润滑蛋白通过调节滑膜炎症维持颞下颌关节稳态
Soichiro Negishi,Kazuhiro Shibusaka,Miki Maemura et al.
Soichiro Negishi et al.
Introduction: Temporomandibular joint osteoarthritis (TMJ-OA) is a degenerative joint disease characterized by cartilage degeneration, synovial inflammation, and subchondral bone remodeling, yet its molecular pathogenesis...
PET/EVOH nonwoven fabrics support in vitro expansion of mesenchymal stem cells with high differentiation potential [0.03%]
PET/EVOH非织造布对间充质干细胞体外增殖及多向分化能力的影响研究
Yu-Min Chen,Chihoko Tokoda,Yasuhiko Tabata
Yu-Min Chen
Cell expansion under three-dimensional (3D) condition has been shown to better preserve cellular properties by mimicking the native microenvironment, thereby creating a more physiologically relevant culture system. This study investigated t...
Qianzheng powder promotes facial nerve regeneration via BDNF/TrkB/CREB pathway activation [0.03%]
启正粉通过激活BDNF/TrkB/CREB通路促进面神经再生
Liang Chen,Chaoqun Wang,Lixin Jiang et al.
Liang Chen et al.
Introduction: Facial nerve injury (FNI) is a common peripheral neuropathy that severely impairs facial function and quality of life. Qianzheng Powder (QZP) is a traditional Chinese herbal formula used to treat facial para...
Hypoxia-preconditioned bone marrow mesenchymal stem cell-derived exosomes ameliorate knee osteoarthritis by promoting cartilage regeneration and alleviating pain in rats [0.03%]
缺氧预处理骨髓间充质干细胞衍生的外泌体通过促进软骨再生和缓解疼痛改善膝关节炎的功效研究
Binbin Zhang,Chuan Lu,Bin Dou et al.
Binbin Zhang et al.
Objective: Knee osteoarthritis (KOA) is the most prevalent subtype of arthritis, characterized by progressive degeneration of articular cartilage. The present study aimed to investigate the reparative potential of exosome...
Influence of donor-recipient age differences in allogenic rat thyroid transplantation [0.03%]
供受者年龄差别对异基因鼠甲状腺移植的影响
Ayumi Arauchi,Katsuhisa Matsuura,Tatsuya Shimizu
Ayumi Arauchi
Introduction: Regenerative medicine for tissue dysplasia, hypoplasia, and functional impairment of tissues and cells has advanced considerably, and thyroid disease is no exception. Inducing differentiation of thyroid cell...