Alveolar epithelial type 2 cells in acute lung injury and acute respiratory distress syndrome: spatiotemporal fate and regulation [0.03%]
急性肺损伤和急性呼吸窘迫综合征中肺泡II型上皮细胞的时空命运与调控机制研究
Wanda Bi,Rui Wang,Saiying Hou et al.
Wanda Bi et al.
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) present significant challenges in critical care, with high mortality rates and limited treatment options. Alveolar epithelial type 2 (AT2) cells are central to lung repa...
O-linked β-N-acetylglucosamine modification in diabetic foot ulcer pathogenesis [0.03%]
O-连接β-N-乙酰氨基葡萄糖修饰在糖尿病足溃疡发病机制中的作用
Bingxue Qi,Siyang Chai,Yang Chen et al.
Bingxue Qi et al.
O-linked β-D-N-acetylglucosamine (O-GlcNAc) modification represents a common form of posttranslational glycosylation orchestrated by two pivotal enzymes, namely, O-GlcNAc transferase and O-GlcNAcase. In recent years, emerging research has ...
Evolving functional hydrogel strategies for cartilage engineering: from fundamentals to functional regeneration [0.03%]
用于软骨组织工程的智能水凝胶策略及功能化再生研究进展
Aikang Li,Jingtao Huang,Jiaqing Chen et al.
Aikang Li et al.
Articular cartilage injury is a significant concern in osteoarthritis (OA), and while traditional pharmacological treatments and surgical interventions have provided some pain relief and promoted cartilage regeneration to a certain extent, ...
From injury to integrity: tissue engineering solutions in combined bone repair and regeneration and muscle repair [0.03%]
从创伤到完整：联合骨修复和再生及肌肉修复的组织工程解决方案
Yesheng Jin,Yixue Huang,Jia Wang et al.
Yesheng Jin et al.
The musculoskeletal system is essential for human movement. However, the increasing incidence of complex musculoskeletal injuries, which involve substantial loss of soft (muscle, skin) and hard (bone) tissues poses significant clinical chal...
Tao Zhang,Youjing Yang,Junyu Jiang et al.
Tao Zhang et al.
Glucose metabolism is the core process by which cells obtain energy, providing adenosine triphosphate and metabolic intermediates through glycolysis and the tricarboxylic acid cycle and supporting cell proliferation, migration, and function...
Advancing injectable hydrogels for wound treatment: targeted control of oxidative stress toward personalized regeneration [0.03%]
用于伤口治疗的注射型水凝胶研究进展：面向个体化修复的氧化应激靶向调控
Thai Thanh T Hoang,Cuong Hung Luu,Joo Hee Kim et al.
Thai Thanh T Hoang et al.
Wound injuries, including severe burns, diabetic foot ulcers, and chronic skin defects, remain a significant clinical burden due to their complexity, susceptibility to infection, and impaired healing, particularly in elderly individuals and...
Nuclear fragile X mental retardation-interacting protein 1-mediated ribophagy regulates immune function of dendritic cells in polymicrobial sepsis [0.03%]
核糖体自噬调节蛋白1通过核糖体自噬调节多微生物感染诱发的脓毒症中的树突状细胞免疫功能
Li-Yu Zheng,Peng-Yi He,Peng-Yue Zhao et al.
Li-Yu Zheng et al.
Background: Dendritic cells are crucial in the development of sepsis, yet the effect of ribophagy on dendritic cell activation remains unclear. This study aimed to investigate the potential role of nuclear fragile X menta...
Ruiqi Chen,Hongbiao Xu,Xueshi Li et al.
Ruiqi Chen et al.
Oxidative stress is an inherent pathophysiological feature in burn wound healing. Severe burns trigger rapid changes in patients' conditions, leading to ischemia-reperfusion injury from early fluid resuscitation, neuroendocrine stress, and ...
Precision removal of uneven skin tissue at the micrometer level via focus-corrected femtosecond-laser ablation [0.03%]
焦距矫正飞秒激光消融技术实现微米级皮肤组织精细祛除
Mingzhou Yuan,Xu He,Guangtao Huang et al.
Mingzhou Yuan et al.
Background: From the perspective of aesthetic surgery and regenerative medicine, the precision of surgical instruments is critical for preventing aesthetic complications during procedures such as skin debridement and the ...
Neutrophil extracellular traps in sepsis: trade-off between pros and cons [0.03%]
脓毒症中的中性粒细胞胞外陷阱的利弊关系
Fengying Liao,Jiangbo Fan,Rui Wang et al.
Fengying Liao et al.
Sepsis, a life-threatening syndrome driven by dysregulated immune responses to infection, presents significant global health challenges with high mortality rates. Neutrophil extracellular traps (NETs), composed of deoxyribonucleic acid and ...