Sugar-induced cell death (SICD) in Saccharomyces cerevisiae: insights into nitrogen-mediated rescue and apoptotic cell death pathways [0.03%]
酵母菌中的糖诱导性细胞死亡（SICD）：探讨氮介导的拯救及凋亡型细胞死亡路径的新见解
Raveena Parbhudayal,Hai-Ping Cheng
Raveena Parbhudayal
Sugar-induced cell death (SICD) is a phenomenon observed in Saccharomyces cerevisiae whereby cells rapidly lose viability in glucose-only solutions. One theory suggests that SICD occurs due to an imbalance in nitrogen and carbon, however, l...
Thomas Brüser,Carsten Sanders
Thomas Brüser
The twin-arginine translocation (Tat) system is the only general pathway for the transport of folded proteins across energized biological membranes. It is found in the bacterial or archaeal cytoplasmic membrane, the plant thylakoid membrane...
TOR-dependent regulation of the yeast homolog of the juvenile Batten Disease-associated gene CLN3 [0.03%]
酵母Batten病相关基因CLN3同源物的TOR依赖性调节机制研究
Vijaykumar Pillalamarri,Samuel W M Gatesy,Amanda E Grassel et al.
Vijaykumar Pillalamarri et al.
The Juvenile form of Batten disease is a neurodegenerative disease with symptoms starting in the first decade and ending in death in the third decade of life. The gene defective in this form of Batten disease, CLN3, is conserved in eukaryot...
From the gut to the lungs: The role of gut microbiota in chronic obstructive pulmonary disease and related research progress [0.03%]
从肠道到肺：肠道菌群在慢性阻塞性肺疾病中的作用及研究进展
Simin Yang,Shuting Zeng,Yongan Deng et al.
Simin Yang et al.
Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disease with high morbidity and mortality. Existing treatment methods are difficult to effectively curb disease progression, highlighting the urgency to explore new p...
Metagenomic and microbiological analyses of historical manuscripts for bacterial community profiling and bacteria-related biodeterioration assessment [0.03%]
基于宏基因组和微生物分析鉴定文献古籍上的细菌群落及生物腐蚀菌评估研究
Esra Keles,Ozge Celik
Esra Keles
Bacteria are important agents in the biodeterioration of cultural heritage objects, including historical manuscripts. Characterizing bacterial communities and generating robust microbiological data has therefore become crucial for conservat...
Protein arginine methyltransferases in protozoan parasites: a new path for antiparasitic chemotherapy? [0.03%]
蛋白质精氨酸甲基转移酶在原生动物寄生虫中的作用：抗寄生虫化疗的新途径？
Gustavo D Campagnaro,Sébastien Pomel
Gustavo D Campagnaro
Protein arginine methyltransferases (PRMTs) catalyse the transference of methyl groups from S-adenosylmethionine to arginine residues in substrate proteins, a post-translational modification widespread among eukaryotes. The change in size a...
Genetic make-up and regulation of the L-lysine biosynthesis pathway in Vibrio natriegens [0.03%]
盐养青杆菌L-赖氨酸生物合成途径的遗传组成和调控研究
Elly Straube,Johannes Radde,Thi Van Anh Tran et al.
Elly Straube et al.
Vibrio natriegens, the fastest growing non-pathogenic microorganism known to date, has emerged as a highly promising chassis strain for synthetic biology and biotechnology applications. This study analysed the make-up and regulation of the ...
Overcoming phagocytosis resistance of hypervirulent Klebsiella pneumoniae by directly targeting capsules [0.03%]
通过直接针对包膜克服高毒性的肺炎克雷伯菌的吞噬抵抗作用
Shogo Tsubaki,Touya Toyomoto,Rika Tanaka et al.
Shogo Tsubaki et al.
Capsular polysaccharides (CPS) are key virulence factors in Klebsiella pneumoniae and are closely associated with the K1 and K2 hypervirulent serotypes. Herein, we demonstrate that introducing nonspecific RNA (sgRNA) into K. pneumoniae ATCC...
VapA/Scs2 sustains polarized growth in Aspergillus nidulans by maintaining AP-2-mediated apical endocytosis [0.03%]
VapA/Scs2通过维持AP-2介导的顶端内吞作用来维持嗜渗枯草芽孢杆菌的极性生长
Xenia Georgiou,Sofia Politi,Sotiris Amillis et al.
Xenia Georgiou et al.
Growth of filamentous fungi is highly polarized requiring the coordinated apical delivery of cell wall components and plasma membrane (PM) material, primarily lipids and proteins, to hyphal tips via conventional vesicular secretion. Fungal ...
Regulation of extracellular vesicles for protein secretion in Aspergillus nidulans [0.03%]
烟曲霉分泌蛋白的细胞外囊泡调控机制研究
Rebekkah E Pope,Patrick Ballmann,Lisa Whitworth et al.
Rebekkah E Pope et al.
Fungi were among the first eukaryotes to transition from aquatic to terrestrial life, developing multicellular hyphae, polar growth, and expanded secretomes for nutrient processing, defense, and symbiosis. We present a reliable method for p...