Overcoming phagocytosis resistance of hypervirulent Klebsiella pneumoniae by directly targeting capsules
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Capsular polysaccharides (CPS) are key virulence factors in Klebsiella pneumoniae and are closely associated with the K1 and K2 hypervirulent serotypes. Herein, we demonstrate that introducing nonspecific RNA (sgRNA) into K. pneumoniae ATCC43816 (Kp-pET-sgRNA)... ...
