Halo Nevus as a Self-Limited Model of Melanocyte Autoimmunity: Bridging Vitiligo, Immune Resolution, and Tumor Immunology-A Narrative Review [0.03%]
_HALO 疣作为黑素细胞自身免疫的自限性模型：白癜风、免疫反应解决和肿瘤免疫学之间的桥梁-叙述性综述
Giulio Tosti
Giulio Tosti
Halo nevus (HN), also known as Sutton nevus or leukoderma acquisitum centrifugum, is a melanocytic lesion characterized by a depigmented halo surrounding a central nevus. Although HN is a benign dermatological condition, increasing evidence...
Non-Melanocytic Histopathological Clues for Melanoma Diagnosis: A Practical Review of Solar Elastosis, Stromal Regression, and Epidermal Reaction Patterns. Do Old-School Clues Still Matter? [0.03%]
有关诊断黑色素瘤的非黑素细胞组织病理线索：日光弹性病、基质退行和表皮反应模式的老派线索还有意义吗？一项实用综述
Michail Sofopoulos
Michail Sofopoulos
Histopathologic melanoma diagnosis extends beyond melanocytic cytology to encompass non-melanocytic features: solar elastosis patterns, stromal regression, adnexal relationships, epidermal reaction patterns, and the host inflammatory respon...
Exploring β3-Adrenergic Receptor, HIF-1α, and CD31 Interplay in the Microenvironment of Atypical Melanocytic Lesions [0.03%]
探讨非典型黑色素病变微环境中的β3肾上腺素能受体、HIF-1α和CD31的相互作用
Eugenia Belcastro,Giuseppe Nicolò Fanelli,Cristian Fidanzi et al.
Eugenia Belcastro et al.
Background: Melanoma incidence is rising rapidly worldwide and stands out due to its high lethality. Despite advances in clinical treatment and in understanding melanoma-sensitive genes and molecular pathogenesis, a specific area of ongoing...
Hydroxychloroquine-Induced AGEP with Positive Rechallenge: A Case Report and Mini Review of the Literature [0.03%]
羟氯喹引起的急性通用性发疹性脓疱病的病例报告及文献简述
Kristijan Jovanović,Tamara Umeljic Sočević,Milos Stepovic et al.
Kristijan Jovanović et al.
Background/objectives: Hydroxychloroquine is widely used in the treatment of autoimmune and dermatologic diseases; however, it may rarely induce severe cutaneous adverse reactions. Acute Generalized Exanthematous Pustulos...
Diagnosis of Syphilis in Paraffin-Embedded Skin Biopsies: Comparison of Treponema pallidum Immunohistochemistry and Polymerase Chain Reaction in Primary and Secondary Stages of Disease [0.03%]
暗视野显微镜下梅毒螺旋体与皮肤石蜡标本中的TP-IHC和PCR对比研究及临床分析
Charlotte C Fuchs,Bastian Stoffers,Stephan A Braun et al.
Charlotte C Fuchs et al.
Syphilis remains one of the most prevalent sexually transmitted infections. Serology is the diagnostic gold standard, but skin biopsies aid in ambiguous cases. Treponemas can be detected in tissue by immunohistochemistry (IHC) and polymeras...
Mitotic Proliferative Nodule Within a Giant Congenital Nevus: One Case Report and Updated Review [0.03%]
先天性巨大黑素斑中的增生性结节一例及文献复习
Philippe Drabent,Nicolas Macagno,Sylvie Fraitag
Philippe Drabent
Proliferative nodules (PNs) are benign, well-limited melanocytic proliferations that can occur within congenital nevi, particularly larger ones. Although they may mimic melanoma clinically and histologically, PNs are characterized by a mono...
Cutaneous Melanoma in Adolescents and Young Adults Versus Older Patients: Clinical and Histopathological Differences in Western Romania [0.03%]
青少年和年轻成人黑色素瘤与老年患者的区别——西罗马尼亚的临床及病理分析
Bianca Roxana Natarâş,Sorina Maria Tăban,Aura Jurescu et al.
Bianca Roxana Natarâş et al.
Aim: This study aimed to identify the clinical and pathological features of primary cutaneous melanomas in young patients, comparing them with those of older patients. ...
Phatcharawat Chirasuthat,Supaporn Suwanchote,Tanaporn Borriboon
Phatcharawat Chirasuthat
A 23-year-old man reported a 3-year history of slowly growing, slightly itchy, flesh-colored papules on the distal glans penis. He denied any history of trauma or previous treatment. Additionally, he experienced no difficulties with urinati...
Perineuriomatous Melanocytic Nevus: A Case Report of a Rare and Underreported Melanocytic Lesion [0.03%]
关于一种罕见的和被低估的黑色素细胞病变的病例报告：皮下黑素细胞神经鞘痣
Muhammad N Mahmood,Eunice Y Chow
Muhammad N Mahmood
Melanocytic nevi exhibiting perineuriomatous differentiation are rare and pose significant diagnostic challenges due to their low incidence and morphological resemblance to other cutaneous spindle-cell lesions, including desmoplastic melano...
Philippe Drabent,Anne Welfringer,Alejandro A Gru et al.
Philippe Drabent et al.
Cutaneous hematologic neoplasms in children are relatively rare and encompass a wide range of lymphoproliferative and myeloproliferative disorders. This review explores and updates the classification, clinical presentation, diagnostic chall...