Diagnosis of Syphilis in Paraffin-Embedded Skin Biopsies: Comparison of Treponema pallidum Immunohistochemistry and Polymerase Chain Reaction in Primary and Secondary Stages of Disease
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Syphilis remains one of the most prevalent sexually transmitted infections. Serology is the diagnostic gold standard, but skin biopsies aid in ambiguous cases. Treponemas can be detected in tissue by immunohistochemistry (IHC) and polymerase chain reaction (PC... ...