Gaia Mancuso,Igor Salvadè,Adam Ogna et al.
Gaia Mancuso et al.
Background: Behçet-like syndrome (BLS) refers to the presence of Behçet's disease (BD) features occurring in association with distinct clinical-pathological conditions such as inborn errors of immunity, myeloproliferati...
Tumor Infiltrating Lymphocytes in Cutaneous Squamous Cell Carcinoma-A Systematic Review [0.03%]
皮肤鳞状细胞癌中肿瘤浸润性淋巴细胞-系统评价
Li Yang Loo,Shi Huan Tay,Choon Chiat Oh
Li Yang Loo
Cutaneous squamous cell carcinoma (cSCC) is an immunogenic malignancy with variable immune infiltration and inconsistent responses to checkpoint blockade. Tumor-infiltrating lymphocytes (TILs) influence tumor progression and therapeutic out...
The Need for Standardization of PRAME Immunohistochemistry in Melanocytic Neoplasms [0.03%]
黑素细胞肿瘤中PRAME免疫组化的标准化必要性
Calla M Sullivan,Dominick DiMaio,Scott Lauer et al.
Calla M Sullivan et al.
Accurate diagnosis of melanomas is crucial for proper evaluation and treatment. One immunohistochemical stain frequently utilized is PRAME (PReferentially expressed Antigen in MElanoma), a tumor-associated antigen expressed in most melanoma...
Deeply Pigmented Reticulated Acanthoma with Sebaceous Differentiation Mimicking Cutaneous Malignancy: A Case Report and Review of the Literature [0.03%]
深染网状棘皮瘤伴脂质分化似皮肤恶性肿瘤：1例报告及文献复习
Padol Chamninawakul,Xiaotian Wu,Joyce S S Lee
Padol Chamninawakul
Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous neoplasm. Its variable clinical presentation frequently mimics both benign and malignant entities, posing a significant diagnostic challenge. We report ...
Hypothetical Abductive Reasoning in Dermatology and Dermatopathology [0.03%]
假说 abduction 在皮肤科和皮肤病学中的应用
Carlo Francesco Tomasini,Lorenzo Magnani
Carlo Francesco Tomasini
Abductive reasoning, or abduction, is a key process in scientific discovery and medical diagnosis. In everyday dermatology and dermatopathology, however, it functions as the practical engine behind differential diagnosis, clinicopathologic ...
Aysin Kaya,Jean-Hilaire Saurat,Nathalie Satta et al.
Aysin Kaya et al.
In this study we evaluated the expression of Angiopoietin 1, Angiopoietin 2, and Tie2 by immunohistochemistry in the skin of 10 patients with erythemato telangiectatic and papulopustular rosacea. Significantly increased expression of Tie2 a...
Artificial Intelligence for Lentigo Maligna: Automated Margin Assessment via Sox-10-Based Melanocyte Density Mapping [0.03%]
基于Sox-10的黑色素细胞密度映射的恶性雀斑样黑色素瘤自动边缘评估人工智能算法
Rieke Löper,Lennart Abels,Daniel Otero Baguer et al.
Rieke Löper et al.
Lentigo maligna (LM) is a melanoma in situ with high cumulative sun damage. Histological evaluation of resection margins is difficult and time-consuming. Melanocyte density (MD) is a suitable, quantifiable, and reproducible diagnostic crite...
Sumeyye Ozer,Priya Agarwal,Noah Musolff et al.
Sumeyye Ozer et al.
Melanoma is a highly aggressive skin cancer primarily linked to ultraviolet (UV) radiation. However, the potential role of ionizing radiation from radiotherapy in melanoma development remains unclear. This review synthesizes data from epide...
Translating Features to Findings: Deep Learning for Melanoma Subtype Prediction [0.03%]
特征到发现的迁移学习：用于黑色素瘤亚型预测的深度学习方法
Dorra Guermazi,Sarina Khemchandani,Samer Wahood et al.
Dorra Guermazi et al.
Melanoma subtyping plays a vital role in histopathological diagnosis, informing prognosis and, in some cases, guiding targeted therapy. However, conventional histologic classification is constrained by inter-rater reliability, morphologic o...
Vincent Kimpe,David Alvarez Martinez,Sébastien Menzinger et al.
Vincent Kimpe et al.
A 56-year-old patient presented to our dermatology clinic with asymmetric hyperpigmentation on her lower lip, which had developed over the previous six to twelve months. Her medical history included kidney and pancreas transplants, requirin...