Male infertility as a late side effect of oncological treatment of Hodgkin lymphoma in childhood and adolescents and the possible prevention [0.03%]
儿童及青少年霍奇金淋巴瘤治疗后的男性不育晚期副作用及其可能的预防措施
Michelle Prusak,Katarzyna Brylka,Katarzyna Derwich
Michelle Prusak
As the cohort of childhood and adolescent survivors of Hodgkin lymphoma (HL) continues to grow, the possibility of preserving long-term fertility has only amplified in the last decade. With the increasing success of pediatric cancer treatme...
Diagnostic performance of a radiological Fagotti score assessed on diffusion-weighted magnetic resonance imaging for predicting tumor resectability in ovarian cancer patients: a feasibility study [0.03%]
放射学Fagotti评分在卵巢癌患者中预测肿瘤可切除性方面的诊断性能研究：一项可行性研究
Franziska Siegenthaler,Selma Zurbriggen,Corinne Wyss et al.
Franziska Siegenthaler et al.
Objective: In ovarian cancer, the correct selection of patients for cytoreductive surgery is of great importance. The aim of this study was to evaluate the diagnostic performance of the Fagotti score assessed on preoperat...
Initial experience of spatially fractionated lattice radiation therapy for palliative treatment of pediatric bulky tumors [0.03%]
空间分次格子放射治疗儿科肿瘤的经验初报
Hualin Zhang,Kenneth Wong,Arthur Olch et al.
Hualin Zhang et al.
Purpose: Spatially fractionated radiation therapy (SFRT) has demonstrated high clinical response rates with minimal toxicity in adult patients with bulky tumors, including radioresistant histologies. However, there is lim...
Case Report: Evolution and targeted therapy of an EGFR-mutant large-cell neuroendocrine carcinoma [0.03%]
病例报告：EGFR突变的大细胞神经内分泌癌的演变和靶向治疗
Li Jiang,Xiaowen Yao,Xiuyu Cai et al.
Li Jiang et al.
We report the case of a 47-year-old female non-smoker diagnosed with stage IV large-cell neuroendocrine carcinoma (LCNEC) of the lung harboring an EGFR exon 21 L858R mutation. The patient exhibited a sustained response to first-line osimert...
Randomized pilot study of an individualized multimodal exercise, nutrition, and behavior intervention in breast cancer patients treated with ovarian function suppression: protocol proposal for The OvS Breast ENBI Project [0.03%]
卵巢功能抑制治疗乳腺癌患者的个体化多模式运动、营养和行为干预随机初步研究：OvS乳腺ENBI项目方案提案
Blanca Herrero López,Mónica Castellanos Montealegre,Candelaria Soulas et al.
Blanca Herrero López et al.
Introduction: Breast cancer (BC) is the most common malignancy among women in Spain and worldwide. Ovarian function suppression (OFS) is recommended as an adjuvant strategy for high-risk hormone receptor (HR)-positive pre...
Knowledge and attitudes toward human papillomavirus and cervical cancer prevention among women in the Asir Region, Saudi Arabia: a cross-sectional study [0.03%]
沙特阿拉伯艾塞尔地区妇女的HPV和宫颈癌防治知识和态度：横断面研究
Geetha Kandasamy,Khalid Orayj,Eman Shorog et al.
Geetha Kandasamy et al.
Background: Cervical cancer, mainly caused by Human Papillomavirus infection, is a growing public health concern in Saudi Arabia. Despite the availability of effective vaccination and screening programs in the country, aw...
Haina Yu,Canfeng Lin,Fan Chen et al.
Haina Yu et al.
Background: Patient-derived cancer organoids emerged as an innovative model in basic and translational medicine research, as well as precision medicine. However, most radiation oncologists are still unaware of the value o...
Supersonic gas curtain based ionization beam profile monitor for FLASH proton beam therapy [0.03%]
基于超音速气幕的FLASH质子放疗束流轮廓监测离子化装置
Milaan Patel,Narender Kumar,Farhana Thesni et al.
Milaan Patel et al.
Introduction: FLASH Proton Beam Therapy (FLASH-PBT) combines the precision targeting ability of proton beam with radiobiological advantage of FLASH effect at ultra-high dose rates (> 40 Gy/s) to improve tumor control whil...
Engineered multifunctional transforming growth factor-β type II receptor ectodomain fusions for oncology applications [0.03%]
用于肿瘤学应用的工程化多功能转化生长因子-β型Ⅱ受体细胞外区融合蛋白
Anne E G Lenferink,John C Zwaagstra,Jason Baardsnes et al.
Anne E G Lenferink et al.
Introduction: The transforming growth factor-β (TGF-β) superfamily consists of a large number of evolutionarily conserved and structurally related polypeptide growth factors. TGF-β elicits a wide range of context-depen...
Intratumoral heterogeneity and potential treatment strategies in small cell lung cancer [0.03%]
小细胞肺癌的肿瘤内异质性和潜在治疗策略
Yunke Yang,Nana Liu,Jiaji Wu et al.
Yunke Yang et al.
Small cell lung cancer (SCLC) is a highly aggressive malignancy characterized by early metastasis and poor prognosis due to the limited efficacy of current treatments. Although initially responsive to chemotherapy and radiotherapy, the majo...