Toripalimab plus gemcitabine and cisplatin induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma: a retrospective study [0.03%]
特瑞普利单抗联合吉西他滨和顺铂诱导化疗治疗局部区域晚期鼻咽癌的疗效：一项回顾性研究
Renba Liang,Ling Lei,Xinxiao Li et al.
Renba Liang et al.
Objective: To explore the efficacy and safety of toripalimab combined with gemcitabine and cisplatin (GP) induction chemotherapy and sequential concurrent chemoradiotherapy in LANPC treatment. ...
Establishment of a CT-based radiomic feature robustness databank for OPC patients via image perturbation in a multi-institutional study: a practical method to safeguard model generalizability [0.03%]
基于多中心研究中通过图像干扰建立OPC患者CT影像组学特征稳健性数据库：一种实用的保护模型泛化能力的方法
Yongqiang Wang,Alex Zwanenburg,Jiang Zhang et al.
Yongqiang Wang et al.
Purpose: To guide the preselection of highly repeatable radiomic features (RFs) in downstream analysis without further analysis its repeatability, a detailed radiomic feature robustness databank (RF-RobustDB) was establis...
Caprine herpes virus-1 reduces cell viability and enhances chemosensitivity in breast cancer cells [0.03%]
山羊疱疹病毒1型降低乳腺癌细胞活力并增强其化疗敏感性
C A Iannuzzi,F Pagano,M Tomeo et al.
C A Iannuzzi et al.
Introduction: Oncolytic viruses (OVs) are promising therapeutic agents in oncology that directly lyse tumor cells, modulate the immune response, and alter the tumor microenvironment. Non-human OVs offer advantages over th...
The oncometabolite R-2-hydroxyglutarate inhibits microglial activation via the FTO/NF-κB pathway [0.03%]
D-2-羟基戊二酸通过FTO/NF-κB信号抑制小胶质细胞激活
Lu Wang,Huiting Zhang,Xifeng Jing et al.
Lu Wang et al.
Introduction: Mutations in isocitrate dehydrogenase 1 (mIDH1) generate the oncometabolite (R)-2-hydroxyglutarate (R-2HG), which promotes tumorigenesis by inhibiting α-ketoglutarate-dependent enzymes and altering the epig...
PARP inhibitors as radiosensitizers: a comprehensive review of preclinical evidence and clinical applications [0.03%]
PARP抑制剂作为放射增敏剂：前期临床证据和临床应用的全面回顾
Xiaodong Luo,Shuo Gao,Kaiyang Sun et al.
Xiaodong Luo et al.
Poly (ADP ribose) polymerase 1 (PARP1) plays a central role in the response of DNA damage induced by tumor radiotherapy. This paper systematically reviewed the structural and functional characteristics of PARP1 and its molecular mechanism i...
BAG3 in human tumors [0.03%]
人肿瘤中的BAG3蛋白质
Paola Manzo,Anna Lisa Cammarota,Jelena Dimitrov et al.
Paola Manzo et al.
Previous studies identified BAG3 as a stress-induced protein with pro-survival functions in various tumors. Based on this assumption, we analyzed the expression and secretion of BAG3 in 24 cancer cell lines representing ten types of cancer ...
Application of holographic imaging combined with real-time ultrasound-guided robot-assisted partial nephrectomy in the treatment of completely endophytic renal tumours: a retrospective cohort study comparing with pure laparoscopic surgery [0.03%]
结合实时超声波引导的全息成像机器人辅助部分肾切除术在完全内生性肾脏肿瘤治疗中的应用：与纯腹腔镜手术比较的回顾队列研究
Feihu Tang,Tongbin Gao,Yuan Gao et al.
Feihu Tang et al.
Background: To compare the perioperative outcomes and renal function preservation between holographic imaging combined with real-time ultrasound-guided robotic-assisted partial nephrectomy (RAPN) using the Da Vinci system...
Neoadjuvant chemotherapy versus surgery alone in locally advanced esophageal squamous cell carcinoma: a propensity-matched real-world study [0.03%]
新辅助化疗与单纯手术治疗局部晚期食管鳞癌的疗效对比：倾向匹配的真实世界研究
Yuchen Wang,Zhifeng Yue,Zhifeng Li et al.
Yuchen Wang et al.
Background: The therapeutic value of neoadjuvant chemotherapy (NAC) for locally advanced esophageal squamous cell carcinoma (ESCC) remains uncertain compared to surgery alone (SA), particularly in real-world settings. Thi...
Impact of histological and clinical parameters on resection status and recurrence probability in head and neck basal cell carcinomas [0.03%]
头颈部基底细胞癌的切除情况和复发概率受组织学和临床参数的影响
Felix Deffner,Givi Magradze,Kia Melzer et al.
Felix Deffner et al.
Objectives: This study aims to identify histological and clinical parameters associated with an R1 resection status and the recurrence rate in surgically treated basal cell carcinomas (BCC) and to evaluate the impact of a...
High-intensity focused ultrasound as a combined approach for the treatment of recurrent low-grade endometrial stromal sarcoma: a case report and literature review [0.03%]
高强度聚焦超声联合治疗复发低级别子宫内膜间质肉瘤1例及相关文献复习
Huihui Chen,Xiaonan Shang,Yue Shen et al.
Huihui Chen et al.
Background: Surgery is the primary treatment for Endometrial Stromal Sarcoma (ESS), however, a substantial proportion of patients with ESS experience recurrence or metastasis. Currently, surgery and local ablation are the...