Gliadel use in a pregnant patient with malignant glioma: a case report [0.03%]
有关恶性胶质瘤孕妇使用Gliadel的病例报告
Vishnu Venkitasubramony,Meghan Tahbaz,Kian A Huang et al.
Vishnu Venkitasubramony et al.
Malignant gliomas during pregnancy represent a rare and complex clinical challenge, with limited data to guide management. We report a case of a 35-year-old woman with World Health Organization (WHO) grade III anaplastic astrocytoma who pre...
Diabetes-associated differentially expressed genes as prognostic biomarkers and therapeutic targets in endometrial cancer: a comprehensive molecular analysis [0.03%]
糖尿病相关差异表达基因作为子宫内膜癌预后生物标志物和治疗靶点的全面分子分析
Ting Zhang,Ruiqing Sun,Xuejun Lian et al.
Ting Zhang et al.
Background: Uterine corpus endometrial carcinoma (UCEC) is a prevalent malignancy increasingly observed in patients with diabetes mellitus. A comprehensive understanding of the intricate molecular interplay between diabet...
Explainable machine learning model predicts response to adjuvant therapy after radical cystectomy in bladder cancer [0.03%]
可解释的机器学习模型预测膀胱癌根治术后辅助治疗反应
Jian Hou,Yi Ding,Runlin Feng et al.
Jian Hou et al.
Purpose: Radical cystectomy (RC) is the standard treatment for muscle-invasive and select high-risk non-muscle-invasive bladder cancer. Despite definitive surgery, recurrence and progression remain major clinical concerns...
Dual oncogenic role of RNF220 in AML: linking metabolic rewiring to cell proliferation and immune evasion [0.03%]
RNF220在急性髓系白血病中的双重致癌作用：连接代谢重构与细胞增殖和免疫逃逸
Bixia Li,Shi Jiang,Yao Xu et al.
Bixia Li et al.
Background: Acute myeloid leukemia (AML) remains a clinical challenge with suboptimal long-term survival. While circular RNAs derived from the RNF220 host gene have been implicated in AML pathogenesis, the functional role...
Prognostic value and early response stratification of a multi-biomarker panel in cervical cancer patients undergoing chemoradiotherapy [0.03%]
用于接受同步放化疗的宫颈癌患者的预后价值和早期反应分层的多生物标志物模型
Yu Wang,Na Gan,Shan Ning et al.
Yu Wang et al.
Aims: Despite progress in chemoradiotherapy (CRT), outcomes in cervical cancer still vary widely. Minimally invasive biomarkers may enable risk stratification and treatment optimization. ...
DLX2 promotes gastric cancer epithelial- mesenchymal transition and malignant progression through the PI3K/AKT signaling pathway [0.03%]
DLX2通过PI3K/AKT信号通路促进胃癌上皮间质转化及恶性进展
Wenjing Chen,Xietao Chen,Xuanfu Chi et al.
Wenjing Chen et al.
Introduction: Gastric cancer (GC) is a major health challenge globally, with poor outcomes often due to late-stage diagnosis and aggressive tumor behavior. This study examines the role of DLX2 in GC progression, focusing ...
Unmet needs in patients with acute myeloid leukemia ineligible for intensive approaches: perspectives from a European expert panel [0.03%]
欧洲专家小组视角：不适合强化治疗的急性髓系白血病患者未满足的需求
Felicetto Ferrara,Klaus Geissler,Priyanka Mehta et al.
Felicetto Ferrara et al.
Acute myeloid leukemia (AML) is primarily a disease of the elderly, with increasing age associated with worse outcomes. Treatment options include intensive chemotherapy, hypomethylating agents with/without venetoclax, and best supportive ca...
Aggressive atypical cystic fibromatosis of the pancreas: a case report and literature review [0.03%]
胰腺激进异型囊性纤维瘤1例并文献复习
Xianhong Yang,Zhenji Xu,Yangyingqiu Liu et al.
Xianhong Yang et al.
Aggressive fibromatosis of the pancreas (AFP) is a rare, non-epithelial, aggressive, benign soft tissue tumor of the pancreas that is characterized by β-catenin-positive expression. Due to its rarity, it is often misdiagnosed as a malignan...
EBV-positive small cell neuroendocrine carcinoma of the nasopharynx with cervical lymph node metastasis: a case report and literature review [0.03%]
鼻咽部 Epstein-Barr病毒阳性小细胞神经内分泌癌合并颈部淋巴结转移的病例报告和文献复习
Jincai Xue,Wenjuan Ma,Xudong Liu et al.
Jincai Xue et al.
Purpose: Investigating the diagnosis and treatment of Epstein-Barr virus-positive small cell neuroendocrine carcinomas of the nasopharynx with cervical lymph node metastasis. ...
Primary breast leiomyosarcoma: prognostic factors and treatment outcomes - a systematic review and case report (1969-2023) [0.03%]
原发性乳腺平滑肌肉瘤的预后因素和治疗结果：系统回顾与病例报告(1969-2023年)
Rui Guo,Weiwei Zhang,Xingli Ji et al.
Rui Guo et al.
Objective: This study aims to investigate the prognostic factors and treatment outcomes of primary breast leiomyosarcoma (PBL). We present a contemporary case of postoperative recurrence and metastasis, and conduct a syst...