Comprehensive molecular profiling of urologic tumors presented in a molecular tumor board: insights from a real-world precision oncology cohort [0.03%]
基于分子肿瘤委员会的泌尿系统肿瘤综合分子分型：来自真实世界精准肿瘤学队列的见解
Maximilian Glienke,Ruth Himmelsbach,Max Zirngibl et al.
Maximilian Glienke et al.
Objectives: Molecular tumor boards (MTBs) have become an integral component of precision oncology, yet data on their real-world impact in urologic cancers are limited. This study aimed to characterize the molecular landsc...
Case Report: Nursing strategies for colon cancer surgery in third-trimester pregnancy [0.03%]
个例报告：三期妊娠结直肠癌手术的护理策略
Shiping Zeng,Jiayou Chen,Yan Luo et al.
Shiping Zeng et al.
Background: Colorectal cancer during pregnancy is rare and poses significant challenges for maternal and fetal care. Postoperative nursing interventions are essential to optimize recovery and prevent complications. ...
An interpretable 18F-FDG PET/CT-based radiomics model for predicting sub-3cm solitary adrenal metastases in cancer patients [0.03%]
基于18F-FDG PET/CT的影像组学模型预测癌症患者小于3厘米的孤立性肾上腺转移瘤 randomness and independence
Wenfeng Feng,Xingjian Wang,Haifeng Cai et al.
Wenfeng Feng et al.
Purpose: To evaluate the potential of an interpretable radiomics model based on 18F-FDG PET/CT for predicting adrenal metastases (AMs) in cancer patients with indeterminate adrenal nodules. ...
Efficacy and safety of anlotinib for the treatment of advanced bone and soft tissue sarcomas: a systematic review and meta-analysis [0.03%]
阿诺芦定治疗晚期骨及软组织肉瘤有效性和安全性的系统评价和meta分析
Zhipeng Li,Peng Fang,Shiwen Shen et al.
Zhipeng Li et al.
Background: Sarcoma, a rare and highly heterogeneous malignant neoplasm originating from mesenchymal tissues, is broadly classified into bone sarcoma and soft tissue sarcoma depending on where they occur. Patients with ad...
M1 macrophage-derived exosomal miR-20b promotes radiosensitization via CCND1 in HPV+ HNSCC [0.03%]
M1型巨噬细胞源性外泌体miR-20b通过CCND1促进HPV阳性HNSCC放射增敏作用
Huan Liu,Siwei Zhang,Zengchen Liu et al.
Huan Liu et al.
Background: Human papillomavirus (HPV) is a significant risk factor for head and neck squamous cell carcinoma (HNSCC). HPV positive (HPV+) HNSCC is more sensitive to radiotherapy and has a better prognosis than HPV negati...
Case Report: SMARCA4-deficient NSCLC with brain metastasis harboring co-mutations in chromatin remodeling and DNA damage repair pathways [0.03%]
病例报告：染色质重塑和DNA损伤修复通路共突变的SMARCA4缺陷型NSCLC脑转移癌
Jiaqin Song,Shikun Yang,Lei Xia
Jiaqin Song
SMARCA4 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4) is the core ATPase subunit of SWI/SNF chromatin remodeling complexes. Its deficiency constitutes a rare and aggressive subtype of non-sm...
Margret Jensdottir,Ole Solheim,Alba Corell et al.
Margret Jensdottir et al.
Background and objectives: Maximal safe resection is the cornerstone of diffuse low-grade glioma (dLGG) management, although epidemiological data are limited. We aim to explore surgical selection, techniques, and outcomes...
Tumor-associated macrophage expression in colorectal adenomas and carcinomas: relationship to Helicobacter pylori infection [0.03%]
肿瘤相关巨噬细胞在结肠直肠腺瘤和癌组织中的表达及其与幽门螺杆菌感染的关系
Wenming Wang,Yueyong Zhu,Yunchao Zhu et al.
Wenming Wang et al.
Objective: This study investigated the association between Helicobacter pylori (H. pylori) infection and the expression of CD163+ and CD86+ tumor-associated macrophages (TAMs) in colorectal adenoma (CRA) and colorectal ca...
The impact of BRCA mutation and hormone receptor status on the outcomes of fertility preservation in breast cancer patients: a systematic review and meta-analysis [0.03%]
BRCA基因突变和激素受体状态对乳腺癌患者生育力保护结局的影响：系统评价和 Meta 分析
Liyu Ye,Weihui Yang,Huiyuan Guan
Liyu Ye
Background: Fertility preservation is a critical aspect of care for young breast cancer (BC) patients undergoing gonadotoxic treatments. BRCA mutation and hormone receptor (HR) status influence tumor biology and treatment...
Stage-specific and regional trends in prostate cancer incidence in Kazakhstan, 2005-2024 [0.03%]
2005-2024年哈萨克斯坦前列腺癌发病率的阶段性及地区性趋势
Gulnur Igissinova,Nurbek Igissin,Indira Kudaibergenova et al.
Gulnur Igissinova et al.
Background: Prostate cancer is a leading malignancy among men globally and continues to be a growing concern in Kazakhstan, where evidence regarding its long-term epidemiological trends is limited. ...