Regional and patient-level determinants of endoscopic utilization in rural healthcare: a multi-level analysis [0.03%]
农村医疗中内镜利用的地区和患者层面决定因素：多水平分析
Muye Ma,Pengfei Li,Zhengyang Lu et al.
Muye Ma et al.
Objective: Despite numerous studies on endoscopic services in urban settings, tailored assessments in rural healthcare remain limited, creating a gap in our understanding of resource-constrained environments. To address t...
Management of multiple primary prostate malignant tumors: case report of synchronous prostatic adenocarcinoma and lymphoma [0.03%]
多原发前列腺恶性肿瘤的管理：前列腺腺癌合并淋巴瘤一例报告
Weihuang Zhuang,Huiqiang Wu,Zhiyin Cai et al.
Weihuang Zhuang et al.
The occurrence of multiple primary prostate malignant tumors is extremely rare and there is no consensus on its diagnosis and treatment. This article presents an elderly male patient with both acinar adenocarcinoma of the prostate and small...
Prognostic analysis and association of the systemic immune-inflammatory index with immune checkpoint inhibitor pneumonitis in patients with non-small cell lung cancer [0.03%]
系统免疫炎症指数对非小细胞肺癌患者免疫检查点抑制剂肺炎的预后分析及关联性研究
Mengyao Cai,Jiangqian Sun,Jingyi Wu et al.
Mengyao Cai et al.
Objective: The Systemic Immune-Inflammatory Index (SII) is a comprehensive indicator reflecting immune response and disease burden. However, its significance in immune checkpoint inhibitor-related pneumonitis (CIP) in cas...
Jin Zhang,Siqi Ren,Shuting Li et al.
Jin Zhang et al.
Objective: T cells and tumor-associated macrophages (TAMs) are critical immune components within the brain tumor microenvironment (TME), yet their precise roles in medulloblastoma remains unclear. In this study, we examin...
Case Report: Metastatic small bowel adenocarcinoma with DNA mismatch repair deficiency in an organ transplant recipient treated with anti-PD-1 immunotherapy [0.03%]
个例报告：器官移植受者中DNA错配修复缺陷性小肠腺癌远端转移的抗PD-1免疫治疗
Quan H Phung,Alexander K Tsai,Byoung U Park et al.
Quan H Phung et al.
We present a case of a 65-year-old woman with a history of kidney and pancreas transplants for type 1 diabetes mellitus who presented with small bowel obstruction and was found to have a poorly differentiated small bowel adenocarcinoma with...
Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer [0.03%]
靶向GJB4以抑制肿瘤生长和诱导胰腺癌铁死亡
Xiangru Zheng,Wenjun Li,Xiaoli Li et al.
Xiangru Zheng et al.
Background: Pancreatic cancer (PC) is a highly malignant type of cancer characterized by poor prognosis and high mortality rate. The role of gap junction protein beta 4 (GJB4) in PC has been scarcely reported. Therefore, ...
Thyroid metastasis from hepatocellular carcinoma: a rare case report and literature review [0.03%]
肝癌甲状腺转移一例并文献复习
Shasha Guan,Qianwen Ye,Panhua Li et al.
Shasha Guan et al.
Background: Thyroid metastasis is a relatively uncommon event in clinical practice, typically occurs in more prevalent primary tumors, including renal cell carcinoma and cancers of the gastrointestinal tract, lungs, and b...
Advancements in artificial intelligence for ultrasound diagnosis of ovarian cancer: a comprehensive review [0.03%]
卵巢癌超声诊断人工智能研究进展：全面回顾
Chenxin Tang,Zhenbin Xu,Hongpeng Duan et al.
Chenxin Tang et al.
Ovarian cancer, as a common gynecological malignancy, is often found at an advanced stage clinically. Thus, improving the early diagnosis of ovarian cancer is crucial for the survival rate of patients. Ultrasound examination is the main met...
The efficacy and safety of chemoimmunotherapy in patients with MSI-L/MSS/pMMR status metastatic colorectal cancer: a systematic review and meta-analysis of randomized controlled trials [0.03%]
微卫星不稳定低度/稳定/匹配力较低的转移性结直肠癌患者中化免联合治疗的有效性和安全性：随机对照试验的系统评价和meta分析
Qi-Jing Zhang,Jia-Xin Zhou,Da-Hai Hu et al.
Qi-Jing Zhang et al.
Background: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, necessitating innovative therapeutic approaches. Most patients with CRC exhibit microsatellite instability-low/stable (MSI...
Hyperprogression disease induced by Sintilimab combined with Oxaliplatin and S-1 after surgery: a case report and literature review [0.03%]
sintilimab联合奥沙利铂和S-1术后引起的超进展疾病一例及相关文献复习
Yaoqi Li,You Wang,Rui Shen et al.
Yaoqi Li et al.
Objective: To investigate the risk factors, underlying mechanisms, and preventive strategies associated with hyperprogressive disease (HPD) induced by immunotherapy. ...