Case Report: Dual resistance to dasatinib/olverembatinib in accelerated-phase cml: identification of a novel SPECC1L-inserted e8a2 BCR::ABL1 transcript and ABL1 V379I mutation [0.03%]
个例报道：加速期CML患者对达沙替尼和奥雷巴替尼耐药的病例中BCR-ABL1融合基因转录本及ABL1突变的新发现
Jingjing Fu,Yangming Tang,Xueqin Ruan et al.
Jingjing Fu et al.
In chronic myeloid leukemia (CML), less than 2% of cases express atypical or rare BCR::ABL1 transcripts. The e8a2 BCR::ABL1 fusion transcript, a rare variant, has been reported in only 20 cases to date, primarily in case reports or case ser...
Prognostic value of the systemic immune-inflammation index in bladder cancer: an update evidence-based analysis [0.03%]
系统免疫炎性指数在膀胱癌中的预后价值：基于证据的更新分析
Jingxing Bai,Yin Huang,Bo Chen et al.
Jingxing Bai et al.
Background: Bladder cancer (BC) prognosis remains challenging to predict accurately with conventional tools. Systemic immune-inflammation index (SII) has emerged as a promising biomarker reflecting the tumor microenvironm...
Real-time AI-guided ultrasound localization method for breast tumor rotational resection [0.03%]
实时人工智能引导的乳腺肿瘤旋转切除超声定位方法
Hang Sun,Hongjie Zhu,Menghan Zhang et al.
Hang Sun et al.
Introduction: Breast tumors, predominantly benign, are a global health concern affecting women. Vacuum-assisted biopsysystems (VABB) guided by ultrasound are widely used forminimally invasive resection, but their reliance...
Case Report: A case series of Lhermitte-Duclos disease with surgical intervention [0.03%]
病例报告：Lhermitte-Duclos病的手术干预系列案例
Ziyang Chen,Min Guo,Xingke Li et al.
Ziyang Chen et al.
Background: Lhermitte-Duclos disease (LDD) is a rare dysplastic cerebellar gangliocytoma often associated with Cowden syndrome and phosphatase and tensin homolog (PTEN) alterations. We report a three-case series focusing ...
ChatGPT-4o, Gemini Advanced and DeepSeek R1 in preoperative decision-making for thyroid surgery: a comparative assessment with human surgeons [0.03%]
术前决策中关于甲状腺手术，ChatGPT-4o、Gemini Advanced和DeepSeek R1与外科医生的比较评估
Long Zou,Peng Zhang,Yu-Qi Jiang et al.
Long Zou et al.
The integration of large language models (LLMs) into surgical decision-making is an emerging field with potential clinical value. This study assessed the preoperative decision-making consistency of ChatGPT-4o, Gemini Advanced, and DeepSeek ...
Combination CBD/THC in the management of chemotherapy-induced peripheral neuropathy: a randomized double blind controlled trial [0.03%]
一项随机双盲对照试验：大麻二酚和四氢大麻酚联合治疗化疗诱导的外周神经病变
Marisa Weiss,Muath Giaddui,Stephanie Kjelstrom et al.
Marisa Weiss et al.
Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) can greatly impair function, leading to disability or truncated treatment in cancer patients. Previous animal studies show that cannabidiol (CBD) and delta-9...
Vacuum-assisted biopsy in the era of low-risk ductal carcinoma in situ active monitoring: real world data and implications [0.03%]
真空辅助活检在导管原位癌主动监测时代的应用：真实世界的数据及其影响
Henrique Lima Couto,Carolina Nazareth Valadares,Aleida Nazareth Soares et al.
Henrique Lima Couto et al.
Background: The short-term oncological safe of active monitoring for ductal carcinoma in situ (DCIS) with low risk (LR-DCIS) of progression to invasive cancers (IC) has been demonstrated. This study evaluates vacuum assis...
Pazopanib in patients with primary multi-metastatic bone Ewing sarcoma [0.03%]
帕唑帕尼治疗原发多骨转移尤因肉瘤患者的效果和安全性评估：一项Ⅱ期研究
Anna Raciborska,Katarzyna Bilska,Jadwiga Węcławek-Tompol et al.
Anna Raciborska et al.
Background: Despite the use of different treatment regimens, patients with primary multi-metastatic Ewing sarcoma disease have a dismal outcome. Lately, pazopanib has been proposed as an effective salvage regimen for soft...
Splenic angiosarcoma with hepatic and cardiac metastases: a case report and literature review [0.03%]
肝和心脏转移的脾血管肉瘤一例报告及文献复习
Fangzheng Chen,Ding Zhao,Haotian Yu et al.
Fangzheng Chen et al.
Splenic angiosarcoma (SA) is an rare malignant tumor in clinical practice, characterized by high malignancy, atypical early symptoms, and a dismal prognosis. In recent years, growing attention has been focused on its diagnosis and treatment...
Real-world safety profile of sonidegib: a disproportionality analysis based on the FDA adverse event reporting system [0.03%]
索拉非尼的真实世界安全性分析：基于美国食品药品监督管理局不良事件通报系统的信号检测研究
Kaidi Zhao,Qinxiao Li,Miao Qin et al.
Kaidi Zhao et al.
Background: Sonidegib is a novel treatment for locally advanced basal cell carcinoma (LaBCC) with demonstrated efficacy and safety in clinical trials. However, its real-world safety profile remains insufficiently characte...