A real-world pharmacovigilance study of romidepsin based on FDA adverse event reporting system database [0.03%]
基于美国食品药品监督管理局不良事件数据库的罗米地辛药物警戒研究
Yuqin Yang,Yaping Huang,Yifan Wang et al.
Yuqin Yang et al.
Background: Romidepsin is a class I-selective histone deacetylase (HDAC) inhibitor indicated for the treatment of adult patients with cutaneous T-cell lymphoma (CTCL) who have received at least one prior systemic therapy ...
Granulomatous cutaneous T-cell lymphoma in a patient with atage IVB of mycosis fungoides: a case report and literature review [0.03%]
一位年龄IVB期蕈样霉菌病患者出现颗粒性皮肤T细胞淋巴瘤的病例报告及文献回顾
Zhu Lin,Jing Xue,Guozeng Ye et al.
Zhu Lin et al.
Background: Granulomatous mycosis fungoides (GMF) represents a distinct pathological variant of mycosis fungoides (MF), mycosis fungoides, originating from memory helper T cells, is the most prevalent form of primary cuta...
Optimizing outcomes with less than more: multi-institutional experience of fast-forward fractionation and the impact of dosimetric parameters on toxicity in breast cancer patients [0.03%]
低剂量高分次放射治疗乳腺癌的多中心研究及剂量学参数对放射毒性的预测价值分析
H Habibullah,M Alotaibi,H Almarzouki et al.
H Habibullah et al.
Background: The FAST-Forward trial demonstrated the non-inferiority of 26 Gy in five fractions compared to 40 Gy in 15 fractions over five years. This study aimed to report observed breast toxicities and examine the impac...
Survival prediction in colorectal cancer liver metastases using machine learning with SHAP-based interpretation [0.03%]
基于SHAP解释的机器学习在结直肠癌肝转移生存预测中的应用
Nan Li,Baoxin Dong,Yu Liang et al.
Nan Li et al.
Background: Colorectal cancer liver metastasis (CRLM) remains a leading cause of cancer-related mortality worldwide. Accurate prognostic stratification is crucial for making individualized therapeutic decisions. Conventio...
Pilot study of topical imiquimod combined with pembrolizumab for unresectable cutaneous metastatic melanoma [0.03%]
咪喹莫特联合派姆单抗治疗不可切除的皮肤转移性黑色素瘤的临床研究
Joseph B Parker,Richard W Joseph,Vera J Suman et al.
Joseph B Parker et al.
Cutaneous metastases occur in up to 20% of patients with advanced melanoma and can be difficult to manage with systemic therapy alone. Pembrolizumab is a standard therapy with limited local treatment options for cutaneous manifestations. Im...
Global research trends of TCM-based nonpharmacologic interventions in breast cancer supportive care: a bibliometric analysis (2000-2025) [0.03%]
基于中医药非药物干预的乳腺癌支持性护理全球研究趋势(2000-2025年):文献计量分析
Qi Wang,Yun Zhu,Huizhen Feng et al.
Qi Wang et al.
Background: With improving survival in breast cancer, supportive care has increasingly focused on long-term, treatment-related symptom clusters (e.g., pain, fatigue, vasomotor symptoms, insomnia, and anxiety) that impair ...
Current positioning and future development of belantamab mafodotin and other antibody-drug conjugates to treat multiple myeloma [0.03%]
Belantamab马夫多汀及其它抗体药物偶联物治疗多发性骨髓瘤的当前定位和未来发展方向分析
Giuseppe Bertuglia,Alessandro Di Nicola,Francesca Gay et al.
Giuseppe Bertuglia et al.
The treatment of Multiple myeloma (MM) has been revolutionized by the advent of immunotherapies. Monoclonal antibodies targeting specific markers greatly contributed to patients' outcome improvement. Antibodies can be conjugated with a toxi...
Multidisciplinary team care and outcomes in FNCLCC grade 3 soft tissue sarcoma: a propensity score-matched and weighted cohort study [0.03%]
FNCLCC三级软组织肉瘤的多学科团队治疗与预后：倾向分值匹配和权重队列研究
Zhangfu Li,Xinyu Li,Baicheng Yang et al.
Zhangfu Li et al.
Background: Multidisciplinary team (MDT) care is widely advocated for soft tissue sarcoma (STS), yet real-world evidence in high-grade disease remains limited and subject to confounding. We investigated whether pre-treatm...
Integrating contrast-enhanced ultrasound to optimize margin delineation in Mohs micrographic surgery for primary dermatofibrosarcoma protuberans: a retrospective cohort study [0.03%]
对比增强超声在莫式显微手术治疗原发性突起皮纤维肉瘤边界划分中的优化作用：回顾性队列研究
Bin Tu,Min-Hong Zou,Yan-Ying Ji et al.
Bin Tu et al.
Introduction: Dermatofibrosarcoma protuberans (DFSP) is characterized by infiltrative "tentacle-like" extensions, making accurate preoperative margin delineation challenging. While high-frequency ultrasound (HFUS) visuali...
DPCrossU-Net: a dual-branch parallel CNN-Transformer network for lung nodule segmentation [0.03%]
基于CNN-Transformer的双分支并行网络用于肺结节分割
Xiya Guan,Wen Zhu,Fangxiang Wu
Xiya Guan
Introduction: Accurate segmentation of lung nodules in CT images is essential for early lung cancer screening and computer-aided diagnosis, yet remains challenging due to small target size, complex boundaries, and the lim...