Trends in liver cancer burden in China and G20: a comparative analysis using GBD 2021 [0.03%]
基于GBD 2021的中国和G20国家肝癌疾病负担变化趋势比较分析
Xiaodi Ma,Lining Jiang,Bing Han et al.
Xiaodi Ma et al.
Objective: To compare liver cancer trends and risk factors in China with those in G20 countries (1990-2021) to inform prevention and resource allocation. ...
Homologous recombination deficiency in breast cancer: genomic characteristics, clinical implications, and predictive value in neoadjuvant therapy [0.03%]
乳腺癌中的同源重组缺陷：基因组特征、临床意义和新辅助治疗预测价值
Jing Huang,Feiyang Luan,Li Yan et al.
Jing Huang et al.
Background: Homologous recombination deficiency (HRD) significantly influences breast cancer development. HRD-positive breast cancer is more sensitive to DNA-targeting cytotoxic drugs, and may benefit from incorporating p...
Prediction of lymphovascular invasion in non-mass enhancement breast cancer using DCE-MRI and clinical-pathological features [0.03%]
结合DCE-MRI和临床病理特征预测非肿块增强型乳腺癌的淋巴管侵犯
Shiqi Guo,Kai Zhao,Hu Xu et al.
Shiqi Guo et al.
Objective: The present study explores the relationship between the distribution patterns of non-mass enhancement (NME) type invasive breast cancer in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and lymp...
Patient-derived organoid-guided precision therapy for a very young woman with multidrug-resistant metastatic breast cancer: a case report [0.03%]
基于患者衍生类器官的精准治疗对中国一名罹患多药耐药转移性乳腺癌的极年轻女性患者的疗效：病例报告
Xiaonuo Zhang,Zhen Zhang,Yidan Chen et al.
Xiaonuo Zhang et al.
We reported a case of a 31-year-old female with therapy-resistant, refractory, and metastatic luminal B breast cancer. Using organoids derived from the patient's malignant pleural effusion for drug screening, we found that the combination o...
Development and validation of nomograms for predicting grade ≥3 diarrhea and neutropenia after abemaciclib combined with endocrine therapy for breast cancer: a multicenter retrospective real-world study [0.03%]
阿贝西利联合内分泌治疗乳腺癌3级及以上腹泻和中性粒细胞减少预测列线图的构建与验证：一项多中心回顾性真实世界研究
Lei Wang,Siyuan Yang,Ji Zhang et al.
Lei Wang et al.
Background: This study aimed to investigate the risk factors associated with grade ≥3 diarrhea and neutropenia, which are the most common adverse events (AEs) leading to discontinuation and dose reduction in patients wit...
The benefits of using confocal laser endomicroscopy in the diagnosis of gastric cancer and precancerous lesions: a case report [0.03%]
共聚焦激光内镜在胃癌及癌前病变诊断中优势的病例报道
Xiaoting Peng,Ya-Ping Zheng,Yan Zhang
Xiaoting Peng
Background: Cases of early gastrointestinal cancers (EGC) are often identified as advanced stages due to the lack of typical clinical manifestations, leading to missed or delayed diagnoses. Confocal laser endomicroscopy (...
Case Report: Bevacizumab-induced renal-limited TMA and FSGS-like lesions in a kidney transplant recipient [0.03%]
个例报道：贝伐单抗致肾移植患者孤立性肾脏TMA和类似FSGS病变一例
Xingxing Jian,Ge Liu,Shuangyan Yu et al.
Xingxing Jian et al.
Bevacizumab, an anti-VEGF agent commonly employed in cancer therapy, can induce renal vascular endothelial and podocyte damage by inhibiting VEGF, leading to renal disease. We present a case of nephrotic syndrome and renal insufficiency ari...
Prognostic value of LODDS in late-onset gastric adenocarcinoma: analysis of SEER, TCGA, and external multicenter cohorts [0.03%]
LODDS在晚期胃腺癌中的预后价值分析：来自SEER、TCGA及多中心外部队列的数据
Hengbo Xia,Yong Qian,Qingqing Pang et al.
Hengbo Xia et al.
Introduction: Accurate survival prediction is crucial for optimizing individualized treatment and follow-up in patients with late-onset gastric adenocarcinoma (LOGA). Traditional lymph node staging systems such as N-stage...
Case Report: Surgery combined with targeted therapy for metastatic anorectal malignant mucosal melanoma [0.03%]
个例报告：手术联合靶向治疗转移性肛门恶性黏膜黑素瘤
Yadong Yao,Pule Liu,Kai Liu et al.
Yadong Yao et al.
Background: Anorectal mucosal melanoma is a rare tumor with a poor prognosis. Timely diagnosis and treatment are essential for improving patient survival. Currently, there is no standardized treatment approach for this di...
Global, regional, national burden of colorectal cancer from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021 [0.03%]
1990年至2021年全球、区域和国家结直肠癌疾病负担及截至2050年的发病率预测：2021年度全球疾病负担研究的系统分析
Shiyu Chang,Yu Chang,Fan Li et al.
Shiyu Chang et al.
Background: Colorectal cancer (CRC) is a common malignant tumor of the digestive system, characterized by a high incidence and mortality rate. This study aimed to investigate the epidemiological characteristics of CRC bet...