Case Report: Evolution and targeted therapy of an EGFR-mutant large-cell neuroendocrine carcinoma
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We report the case of a 47-year-old female non-smoker diagnosed with stage IV large-cell neuroendocrine carcinoma (LCNEC) of the lung harboring an EGFR exon 21 L858R mutation. The patient exhibited a sustained response to first-line osimertinib, with a progres... ...
