Colonic metastasis of a huge soft uterine leiomyoma in a postmenopausal woman: a case report [0.03%]
绝经后女性巨大子宫平滑肌瘤发生结肠转移一例报告
JianXin Tang,RuiBo Xu,XiaoYu Xi et al.
JianXin Tang et al.
Background: .Uterine leiomyomas are the most common benign tumors of the female reproductive system, arising from the overgrowth of smooth muscle tissue within the uterus. Typically, they present as solid, spherical masse...
Temporal dynamics of cisplatin-induced endothelial senescence and its association with cognitive impairment: insights into the medial prefrontal cortex [0.03%]
顺铂诱导内皮细胞衰老的动态变化及其与认知障碍的关系：关于额中皮层的见解
Yue Hei,Sheng-Nan Kong,Juan-Hua Sun et al.
Yue Hei et al.
Background: Chemotherapy-related cognitive impairment (CRCI) poses significant challenges for cancer survivors, with its underlying mechanisms remaining inadequately understood, particularly in the medial prefrontal corte...
Primary breast diffuse large B-cell lymphoma (germinal center B-cell-like subtype): a case report and literature review [0.03%]
弥漫性大B细胞淋巴瘤(GCB亚型)合并乳腺癌1例报告及文献复习
Xiaoxiao Xing,Daixiang Liao,Shiyun Zhang et al.
Xiaoxiao Xing et al.
Background: Primary breast lymphoma (PBL) is a rare type of extranodal lymphoma, of which diffuse large B-cell lymphoma (DLBCL) is the most common histological subtype. Due to its nonspecific clinical and imaging features...
Case Report: Metachronous pancreatic adenocarcinoma following HER2-positive breast cancer and the implications of non-BRCA germline variants with TP53-mutant disease [0.03%]
个例报告：HER2阳性乳腺癌后发生的异时性胰腺导管腺癌及非BRCA基因胚系变异对TP53突变型癌症的意义
Jing Chen,Hui Chun Zhou,Min Hui Fan et al.
Jing Chen et al.
Metachronous pancreatic ductal adenocarcinoma (PDAC) following breast cancer is rare and often linked to pathogenic variants in high-penetrance genes such as BRCA2. We report a case of this clinical scenario lacking classic mutations, which...
Visualizing the vascular-cellular microenvironment in lung cancer brain metastasis via multiparametric fusion of DCE-MRI and DWI [0.03%]
基于DCE-MRI和DWI多参数融合的肺癌脑转移瘤血管-细胞微环境可视化研究
Yonglong Li,Zhen Li,Haotian Wang et al.
Yonglong Li et al.
Background: The heterogeneity of the lung cancer brain metastasis (LCBM) microenvironment limits therapeutic efficacy, while invasive pathological biopsies fail to dynamically assess brain metastasis (BM) comprehensively....
Repurposing risperidone as an anti-angiogenic agent for triple-negative breast cancer: a computational to in ovo investigation [0.03%]
利培酮作为三阴性乳腺癌抗血管生成药物的再利用：从计算到在卵的研究
Anisha Jain,Anil Kumar Belagal Motatis,Chandan Dharmashekar et al.
Anisha Jain et al.
Introduction: Triple-negative breast cancer (TNBC) is a challenging subtype of breast cancer to treat because it lacks the expression of progesterone receptor (PR), estrogen receptor (ER), and human epidermal growth facto...
Integrated molecular and microenvironmental drivers of drug resistance in gastrointestinal cancers: mechanisms, immunotherapy challenges, and precision strategies [0.03%]
胃肠癌症药物耐药的分子机制及免疫治疗策略挑战：整合分子和微环境驱动因素
Heng Xu,Jiaan Lu,Jiangying Wu et al.
Heng Xu et al.
Resistance to chemotherapy, targeted agents, and particularly immunotherapy remains the principal challenge in the management of gastrointestinal malignancies. This review aims to comprehensively delineate the molecular and microenvironment...
Prediction of intracranial response to PD-1/PD-L1 inhibitors therapy in brain metastases originating from non-small cell lung cancer using habitat imaging and peritumoral radiomics: a multicenter study [0.03%]
基于栖息地成像和肿瘤周圍区域影像组学预测非小细胞肺癌脑转移瘤PD-1/PD-L1抑制剂疗效的颅内反应：一项多中心研究
Min Ding,Tianrui He,Jing Yu et al.
Min Ding et al.
Background: Predicting the intracranial efficacy of programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors in non-small cell lung cancer (NSCLC) patients with brain metastasis (BM) remains challenging. The o...
Strategies of neoadjuvant therapy in esophageal cancer: a study on the effects of treatment frequency and surgery interval [0.03%]
术前新辅助治疗食管癌的策略研究：治疗频率和手术间期的影响
Huilai Lv,Bisong Chen,Chunyue Gai et al.
Huilai Lv et al.
Background: Neoadjuvant immunochemotherapy has shown remarkable efficacy in locally advanced ESCC. Therapy cycles and interval to surgery impact treatment efficacy. However, no consensus exists on the optimal cycles or su...
Efficacy and safety of hetrombopag in the treatment of chemotherapy-related thrombocytopenia in solid tumors: a retrospective study [0.03%]
艾曲波帕治疗实体瘤化疗所致血小板减少的疗效和安全性：一项回顾性研究
Yuan Yuan,Qiang Tong,Jia-Hui Liu et al.
Yuan Yuan et al.
Objective: This study aims to evaluate the efficacy and safety of hetrombopag in the management of chemotherapy-induced thrombocytopenia (CIT) among patients with solid tumors, utilizing a retrospective cohort study desig...