Exploring 2D and 3D radiomic models for predicting microvascular invasion in hepatocellular carcinoma: a novel perspective on tumor heterogeneity [0.03%]
从肿瘤异质性的新视角探索肝细胞癌微血管侵犯的二维和三维影像组学模型
Zexin Yin,Meilong Wu,Youyao Li et al.
Zexin Yin et al.
Objective: This study aims to develop models for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC) patients prior to surgery using two-dimensional (2D) and three-dimensional (3D) radiomics features...
A discrete choice experiment analysis to understand patient preferences for multiple myeloma treatments [0.03%]
应用离散选择试验分析了解患者对于治疗多发性骨髓瘤的偏好
Beth Faiman,Hoa H Le,Julie Laurent et al.
Beth Faiman et al.
Introduction: Multiple myeloma (MM) is a malignant plasma cell disorder characterized by the clonal expansion of abnormal plasma cells within the bone marrow. The management of relapsed/refractory multiple myeloma (RRMM) ...
Identification of amino acid metabolism-related gene Leucyl-tRNA synthetase 1 (LARS1) as a potential prognostic and therapeutic target in hepatocellular carcinoma [0.03%]
肝癌中与氨基酸代谢相关的基因亮氨酰-tRNA合成酶1（LARS1）的鉴定及其作为潜在预后和治疗靶点的作用
Qiyu Shi,Yirong Chi,Ziyi Peng et al.
Qiyu Shi et al.
Introduction: Amino acid metabolism plays a critical role in tumorigenesis in hepatocellular carcinoma (HCC). Thus, we explore the amino acid metabolic profile in HCC to construct effective prognosis model and identify no...
Efficacy and survival analysis of neoadjuvant chemotherapy combined with immunotherapy in locally advanced resectable Siewert type II adenocarcinoma of the esophagogastric junction [0.03%]
新辅助化疗联合免疫治疗在可切除的Siewert Ⅱ型食管胃交界部腺癌中的疗效及生存分析
Chunyue Gai,Huilai Lv,Cuili Feng et al.
Chunyue Gai et al.
Background: Neoadjuvant chemotherapy combined with immunotherapy (nCI) has achieved significant results in esophageal and gastric cancers, but its efficacy in Siewert type II adenocarcinoma of the esophagogastric junction...
The paradoxical role of stem cells in osteosarcoma: from pathogenesis to therapeutic breakthroughs [0.03%]
肿瘤干细胞在骨肉瘤中的悖论作用：从发病机制到治疗突破
Zhengbing Su,Xiang Fang,Hong Duan
Zhengbing Su
Osteosarcoma (OS), the most prevalent primary malignant bone tumor in adolescents, exhibits a high metastatic potential and resistance to therapy. This characteristic results in a dismal prognosis in advanced cases even following multimodal...
Bibliometrics and scientometrics analysis of exosomes relevance in hepatocellular carcinoma (2014-2024) [0.03%]
2014-2024年外泌体在肝细胞癌研究中相关性的文献计量和科学计量分析
Kaikui Wu,Guiya Lu,Ruijun Guo et al.
Kaikui Wu et al.
Background: Exosomes have emerged as pivotal players in the pathogenesis, progression, and treatment of hepatocellular carcinoma (HCC), establishing them as a major research focus in recent years. This bibliometric analys...
Shaopeng Zhu,Yunpeng Zou,Jie Guo et al.
Shaopeng Zhu et al.
IQGAP1, a versatile scaffolding protein, critically regulates cytoskeletal organization, cell motility, proliferation, and signaling cascades. Beyond coordinating these cellular functions, it is increasingly recognized as a key driver in ma...
Ronny Westerman,Zhenbao Liu,Rohimah Mohamud et al.
Ronny Westerman et al.
Severe Legionella pneumonia mimicking immune-related pneumonitis after chemoimmunotherapy for lung cancer: a case report [0.03%]
一例肺癌化疗后出现严重军团菌肺炎的病例报告
Haixian Liu,Zhaolei Ding,Lina Xu et al.
Haixian Liu et al.
Background: Immune checkpoint inhibitors (ICIs) have significantly improved survival outcomes and quality of life in patients with various malignancies. Nevertheless, their associated toxicities must not be overlooked. Al...
Stereotactic body radiation therapy for early-stage non-small cell lung cancer: a single-institutional retrospective analysis of outcomes and prognostic factors [0.03%]
立体定向体部放射治疗早期非小细胞肺癌的疗效及预后因素分析
Chengrui Fu,Jigang Dong,Chunhui Li et al.
Chengrui Fu et al.
Background: Stereotactic body radiotherapy (SBRT) is a definitive treatment for medically inoperable early-stage non-small cell lung cancer (NSCLC), yet optimal dose selection and prognostic factors in elderly, high-risk ...