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Case Report: Metachronous pancreatic adenocarcinoma following HER2-positive breast cancer and the implications of non-BRCA germline variants with TP53-mutant disease

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Metachronous pancreatic ductal adenocarcinoma (PDAC) following breast cancer is rare and often linked to pathogenic variants in high-penetrance genes such as BRCA2. We report a case of this clinical scenario lacking classic mutations, which prompted exploratio... ...