Solid-state characterization of lacidipine/PVP K(29/32) solid dispersion primed by solvent co-evaporation [0.03%]
溶剂共蒸发诱导拉西地平/PVP K(29/32)固态分散体系的固态表征研究
Amit Mukharya,Shivang Chaudhary,Niyaz Mansuri et al.
Amit Mukharya et al.
Background: Lacidipine (LCDP) is a 1,4-dihydropyridine derivative categorized as an anti-hypertensive Ca2+ channel blocker having very low solubility, and thus very low oral bioavailability, which presents a challenge to ...
Pankaj H Prajapati,Vijay V Nakum,Chhagan N Patel
Pankaj H Prajapati
Background/aim: The purpose of the study was to prolong the gastric residence time of stavudine by designing its floating tablets and to study the influence of different polymers on its release rate. ...
Formulation and evaluation of an in situ gel-forming ophthalmic formulation of moxifloxacin hydrochloride [0.03%]
一种左氧氟沙星盐酸盐原位凝胶化眼用制剂的制备与评价研究
Sonjoy Mandal,Manjunath Kmj Thimmasetty,Gl Prabhushankar et al.
Sonjoy Mandal et al.
Background/aim: The aim of the present investigation is to prepare and evaluate in situ gel-forming ophthalmic drug delivery system of moxifloxacin hydrochloride. ...
Ocular insert for sustained delivery of gatifloxacin sesquihydrate: Preparation and evaluations [0.03%]
用于持续递送加替沙星一水合物的眼用插入剂的制备和评估研究
Gaurav Khurana,Sandeep Arora,Pravin K Pawar
Gaurav Khurana
Background: Many polymeric systems have been used to fabricate ocular inserts for improve ocular bioavailability and retention to drug of which matrix systems have shown advantages of reduce dosing frequency and increased...
Isolation and characterization of jackfruit mucilage and its comparative evaluation as a mucoadhesive and controlled release component in buccal tablets [0.03%]
Jackfruit粘液的分离、表征及其作为颊片中黏膜粘附和控制释放组分的比较评价
Vidya Sabale,Vandana Patel,Archana Paranjape
Vidya Sabale
Background: The purpose of the present research work was to extract jackfruit mucilage, use it as a mucoadhesive agent, and to develop extended release buccoadhesive tablets with an intention to avoid hepatic first-pass m...
Swatantra Ks Kushwaha,Prachi Saxena,Ak Rai
Swatantra Ks Kushwaha
Amongst the various routes of drug delivery, the field of ocular drug delivery is one of the most interesting and challenging endeavors facing the pharmaceutical scientist for past 10-20 years. As an isolated organ, eye is very difficult to...
Jasjeet K Sahni
Jasjeet K Sahni
In vitro evaluation of Moringa oleifera gum for colon-specific drug delivery [0.03%]
采用体外评价Moringa oleifera胶作为结肠特异性药物递送系统的潜力
Anil Kumar Singhal,Edwin E Jarald,Ahmad Showkat et al.
Anil Kumar Singhal et al.
Background: Moringa gum obtained from stem of the plant Moringa oleifera Lam. belonging to family Moringaceae. Number of naturally occurring polysaccharides obtained from plant (guar gum, inulin), animal (chitosan, chondr...
Dissolution enhancement of glimepiride using modified gum karaya as a carrier [0.03%]
Modified gum karaya作为载体增强格列美脲的溶解度
Manju Nagpal,Rampal Rajera,Kalpana Nagpal et al.
Manju Nagpal et al.
Objective: The aim of present investigation is to enhance in vitro dissolution of poorly soluble drug glimepiride by preparing solid dispersions using modified gum karaya. ...
Formulation and optimization of mucoadhesive bilayer buccal tablets of atenolol using simplex design method [0.03%]
用正交设计方法制备和优化阿替洛尔黏膜粘附双层颊片研究
Sb Shirsand,Sarasija Suresh,Gg Keshavshetti et al.
Sb Shirsand et al.
Introduction: In the present study, mucoadhesive buccal bilayer tablets of atenolol were fabricated with the objective of avoiding first pass metabolism and to improve its bioavailability with reduction in dosing frequenc...