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Solid-state characterization of lacidipine/PVP K(29/32) solid dispersion primed by solvent co-evaporation

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Background: Lacidipine (LCDP) is a 1,4-dihydropyridine derivative categorized as an anti-hypertensive Ca2+ channel blocker having very low solubility, and thus very low oral bioavailability, which presents a challenge to the form... ...