Eplerenone Attenuates Hepatic Oxidative Stress and Mitochondrial Dysfunction Following Renal Ischemia-Reperfusion Injury in Rats [0.03%]
埃坡利非林通过减轻肾缺血再灌注损伤大鼠肝脏的氧化应激和线粒体功能障碍而发挥保护作用
Alireza Barati,Seyed Mohammadmahdi Meybodi,Kimia Moradi et al.
Alireza Barati et al.
Purpose: Acute kidney injury (AKI) is frequently complicated by systemic manifestations, including hepatic dysfunction, largely due to ischemia-reperfusion (I/R) injury. This study investigated the hepatoprotective effect...
Clinical Studies Using Intranasal Therapies for Parkinson's Disease: A Review [0.03%]
帕金森病的鼻用治疗临床研究进展综述
Ramin Vahidi,Mahsa Bukanian,Maryam Kachooeian
Ramin Vahidi
Intranasal delivery is a method of administering medications through the nasal cavity. It offers several advantages, such as rapid absorption, bypassing first-pass metabolism, direct nose-to-brain transport and localized effects. These bene...
Pharmacological Therapies for Bowel Dysfunction After Colorectal Cancer Surgery: A Systematic Review [0.03%]
结直肠手术后肠道功能障碍的药物治疗：系统性回顾
Alimohammad Bananzadeh,Seyed Matin Emami,Seyed Mohammad Kazem Tadayon et al.
Alimohammad Bananzadeh et al.
Introduction: Bowel dysfunction frequently occurs in colorectal cancer (CRC) patients following sphincter-preserving surgeries. This review systematically evaluated the evidence on pharmacological therapies for this compl...
Immunogenicity as a Key Challenge in Tissue Engineering: Toward Clinical Translation [0.03%]
免疫原性作为组织工程向临床转化过程中的关键挑战
Arash Abdolmaleki,Sina Jafari Dargahlou,Hussein A Ghanimi
Arash Abdolmaleki
Psoralen and Seselin Stabilize the α-helix Structure in Lysozyme and Inhibit the α-helix to β-sheet Exchange: An Efficient Anti-Amyloidogenic Mechanism [0.03%]
psoralen和seselin通过稳定溶菌酶中的α-螺旋结构而抑制α-螺旋向β-折叠的转换来成为有效的抗淀粉样物质生成分子机制
Parisa Panah-Amand,Leila Sadeghi,Arezu Marefat et al.
Parisa Panah-Amand et al.
Purpose: More than thirty human proteins have natural propensity to misfold and amyloid fibril formation that are important in the initiation and development of neurodegenerative disease. Therefore, preventing or reversin...
Association of Circular RNAs (circRNAs) in Hepatitis B Virus (HBV) Induced Hepatocellular Carcinoma (HCC): Emerging Diagnostic Biomarkers and Novel Therapeutic Targets [0.03%]
乙肝病毒诱导的肝细胞癌中的环状RNA（circRNA）关联：新兴的诊断生物标志物和新的治疗靶点
Nalira Yaugoob,Kannan Subbaram,Razana Faiz et al.
Nalira Yaugoob et al.
Development of AS1411 Aptamer-Targeted Solid Lipid Nanoparticles to Improve Anticancer Efficiency of Lawsone [0.03%]
用于提高莱扎酮抗癌效率的AS1411适配体靶向固脂纳米粒的开发研究
Sara Gheshlaghi,Armita Sedighidarijani,Afsaneh Maali et al.
Sara Gheshlaghi et al.
Introduction: Lawsone (LWS), a naphthoquinone dye known for its anticancer properties, faces challenges with aqueous solubility, which restricts its therapeutic use. Solid lipid nanoparticles (SLNs) are recognized for enh...
Polymorphic Conversion of Furosemide after Crystallization in Aqueous Polymeric Solution: Crystallite Analysis Using Scherrer vs. Williamson-Hall Equation and Drug Dissolution [0.03%]
基于Scherrer与Williamson-Hall方程的结晶分析技术在评价聚氧乙烯水溶液中呋塞米多晶型转换及溶出行为中的应用研究
Mouli Das,Sk Habibullah,Alisha Khandelwal et al.
Mouli Das et al.
Purpose: Furosemide (FUR) is a potent loop diuretic, practically water-insoluble drug and also known to exhibit polymorphic form I (most stable), form II (metastable), and form III (metastable), and also a poorly stable a...
Biomimetic Scaffold of Chitosan from Litopenaeus vannamei Shrimp Shells Incorporated with Collagen and Hydroxyapatite for Bone Tissue Regeneration [0.03%]
一种用于骨组织再生的壳聚糖仿生支架及其制备方法和应用
Cheryn Ivana,Hendrik Satria Dwi Putra,Nyoman Bayu Wisnu Kencana et al.
Cheryn Ivana et al.
Introduction: The goal of this study was to create a biocompatible bone tissue engineering scaffold from Litopenaeus vannamei shrimp shell chitosan with hydroxyapatite (HAP) and collagen type I (COL I), and to investigate...