Maher Monir Akl,Amr Ahmed
Maher Monir Akl
Angélica Sofía Martínez-Ramírez,José David Nuñez-Ríos,Ana Patricia Juárez-Mercado et al.
Angélica Sofía Martínez-Ramírez et al.
Ovarian carcinoma (OC) is the most lethal gynecological cancer worldwide. Around 95% of patients exhibit recurrence five years after treatment; 80% experience recurrence within 18 months after first-line treatment, and progression-free surv...
Hydrogel Micro/Nanostructures for the Delivery of Oncolytic Viruses: Overcoming Limitations and Improving Efficacy [0.03%]
Chou-Yi Hsu,Saade Abdalkareem Jasim,Jasur Alimdjanovich Rizaev et al.
Chou-Yi Hsu et al.
Oncolytic viruses (OVs) have attracted accumulating attention in cancer therapy owing to their ability to replicate in and kill tumor cells, resulting in the stimulation of immune responses for eradicating residual and distant malignant cel...
Pharmaco-EEG-Based Classification of Psychotropic Activity of a Novel Chromone-Containing Allylmorpholine in Rats [0.03%]
Yuriy I Sysoev,Nikita S Kurmazov,Darya D Shitc et al.
Yuriy I Sysoev et al.
Purpose: Chromone-containing allylmorpholines (CCAMs) are a promising class of compounds that have been shown to have a dose-dependent inhibition effect on locomotion in zebrafish (Danio rerio). However, experiments using...
Shilpa Chaudhary,Keerti Manocha,Praveen Malik et al.
Shilpa Chaudhary et al.
Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2Dm) are increasingly recognized as interrelated metabolic disorders, each contributing to the other's progression. NAFLD, a leading cause of chronic liver disease globally, is ...
Nano-Engineered Cargo for Optimizing Oral Absorption of Tizanidine Nanostructured Lipid Carriers [0.03%]
Mohammed A Bazuhair,Maha H Jamal,Rawabi A Alashari et al.
Mohammed A Bazuhair et al.
Purpose: Tizanidine (TNZ) is a muscle relaxant that works by blocking presynaptic neurons. Due to its inadequate solubility and low oral bioavailability, this medication is classified as a Biopharmaceutics Classification ...
Conditioned Medium from Estradiol-Primed Macrophages Mitigates Adjuvant-Induced Arthritis in Rats [0.03%]
Farshad Yadollahi,Seyyed Meysam Abtahi Froushani,Rahim Hobenaghi
Farshad Yadollahi
Purpose: Macrophages with an anti-inflammatory phenotype are critical for resolving inflammation and preventing chronic tissue injury. Estradiol is known to promote this favorable macrophage profile. This study evaluated ...
The Phenomenon of Antimicrobial Resistance in Southern Italy: An Overview of the Current Situation [0.03%]
Stefano Ruga,Raffaele Petti,Mara Masullo et al.
Stefano Ruga et al.
Purpose: Antimicrobial resistance (AMR) is an escalating global health challenge with region-specific implications. This study investigated AMR prevalence in Southern Italy, with particular attention to demographic variab...
Mahbubeh Rojhannezhad,Zahra Abedi Kichi,Abbas Nikravesh et al.
Mahbubeh Rojhannezhad et al.
Purpose: Rituximab is the primary treatment for non-Hodgkin lymphoma (NHL), one of the most common cancers globally. One of the main challenges associated with rituximab therapy is the decline in its effectiveness over ti...
Investigating the Role of Empagliflozin in the Pathological Progress of Ischemia-Reperfusion Injury in Rat Kidneys: The Involvement of Nitric Oxide [0.03%]
Amin Hasanvand,Abdolreza Tajdar,Azita Zafar Mohtashami et al.
Amin Hasanvand et al.
Purpose: Renal ischemia-reperfusion (RIR) is a pathological condition that can lead to severe outcomes due to damage to kidney structures. Additionally, oxidative stress is triggered by mitochondrial disruption during rep...