MUC1-Driven Guanylin Gene Delivery via Succinylated PEI-9 Nanocarrier for Colorectal Cancer Treatment: An in Silico and In vitro Study [0.03%]
基于硅和体外试验的MUC1驱动的succinylated PEI-9纳米载体递送鸟苷酸素基因治疗结直肠癌研究
Pouria Samadi,Fatemeh Rahbarizadeh,Fatemeh Nouri et al.
Pouria Samadi et al.
Purpose: Addressing colorectal cancer (CRC) poses a significant challenge, demanding the precise delivery of therapeutic agents to eliminate cancer cells while minimizing the impact on healthy cells. The strategic selecti...
Jozélio Freire de Carvalho,Ana Tereza Amoedo Martinez
Jozélio Freire de Carvalho
Ahmed Naueen Nazim,Kannan Subbaram,Razana Faiz et al.
Ahmed Naueen Nazim et al.
Mihály Hegedűs,Mehdi Dadkhah,Lóránt Dénes Dávid
Mihály Hegedűs
Purpose: The negative impact of potential predatory journals has been widely discussed, primarily within academic contexts. However, their influence beyond academia remains underexplored. This study aims to address that g...
Behnaz Mirzaahmadi,Reza Rahbarghazi,Mohammad Karimipour
Behnaz Mirzaahmadi
Purpose: There are effective treatments available for neuropsychiatric disorders; however, numerous factors such as misdiagnosis, delayed diagnosis, varying types of onsets and progression of disorder, as well as long tim...
The Role of Cerebrolysin in Promoting Axonal Regeneration and Functional Recovery after Peripheral Nerve Injury: A Focus on Macrophage Activation [0.03%]
脑神经营养液促进外周神经损伤后轴突再生和功能恢复的作用及其对巨噬细胞活化的影响
Aida Karimian,Arash Abdolmaleki,Asadollah Asadi et al.
Aida Karimian et al.
Purpose: The research investigated the neuroprotective properties of Cerebrolysin regarding functional recovery, axonal regeneration, and macrophage polarization in a rat model of acute sciatic nerve damage. ...
Preclinical and Limited Clinical Evidence for Spirulina in Ulcerative Colitis: A Systematic Review and Meta-analysis [0.03%]
小球藻治疗溃疡性结肠炎的临床前和有限临床证据系统评价和meta分析
Khadije Gorgi,Zahra Ghanbarzadegan,Amir Darkhosh et al.
Khadije Gorgi et al.
Purpose: Ulcerative colitis (UC) is a chronic inflammatory disease of the gastrointestinal tract. This study aimed to systematically review available animal and clinical studies on the effects of spirulina (Arthrospira pl...
Mebendazole-Treated Human Monocyte-Derived Dendritic Cells Represent Promoted Immunogenic Phenotype with Augmented Expression of Inflammatory Markers [0.03%]
美贝达唑治疗的人单核细胞来源的树突状细胞具有促炎表型和炎症标志物表达增强的特点
Shiva Alipour,Sepideh Sohrabi,Amirhossein Mardi et al.
Shiva Alipour et al.
Purpose: Dendritic cells (DCs) play a critical role in regulating immune responses by influencing the balance between immune tolerance and immunogenicity. While mebendazole (MBZ) is known to polarize macrophages toward a ...
Hyaluronic Acid-Functionalized Liposomes for Co-delivery of 5-Fluorouracil and Cannabidiol Against Colorectal Cancer [0.03%]
透明质酸功能化脂质体协同递送5-氟尿嘧啶和大麻二酚用于结直肠癌治疗
Soheil Abbaspour-Ravasjani,Mahdi Zeinali,Leila Asadollahi et al.
Soheil Abbaspour-Ravasjani et al.
Purpose: Colorectal cancer (CRC) is a formidable global health challenge, ranking as the third most prevalent cancer. Conventional treatments like surgery, radiation, and chemotherapy are limited by adverse effects, drivi...
Delivery Systems of mRNA Vaccines in the Treatment of Infectious Diseases: From Lipid Nanoparticles to Next-Generation Platforms [0.03%]
mRNA疫苗递送系统在传染病治疗中的应用：从脂质纳米颗粒到下一代平台
Chou-Yi Hsu,Abdulsalam Abdulsattar Abdulazez,Yasir Qasim Almajidi et al.
Chou-Yi Hsu et al.
The historic accomplishment of mRNA vaccines against SARS-CoV-2 has provided a massive shift in vaccinology, providing a quick, nimble, and powerful platform for infectious disease prevention. This success, however, does not simply stem fro...