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Psoralen and Seselin Stabilize the α-helix Structure in Lysozyme and Inhibit the α-helix to β-sheet Exchange: An Efficient Anti-Amyloidogenic Mechanism

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Purpose: More than thirty human proteins have natural propensity to misfold and amyloid fibril formation that are important in the initiation and development of neurodegenerative disease. Therefore, preventing or reversing amyloi... ...