Contribution of thromboxane a₂ in rat common carotid artery response to serotonin [0.03%]
血清素对大鼠颈总动脉反应中凝血恶烷A2的贡献
Miroslav Radenković,Marko Stojanović,Mirko Topalović
Miroslav Radenković
Serotonin is a vasoactive substance that in different blood vessels mostly induces vasoconstriction. Considering the important role of common carotid artery in brain blood supply, the aims of this study were to investigate the effect of ser...
Production, quality control and pharmacokinetic studies of Ho-EDTMP for therapeutic applications [0.03%]
Ho-EDTMP药物的质量控制、制备及其药代动力学研究
Ali Bahrami-Samani,Reza Bagheri,Amir R Jalilian et al.
Ali Bahrami-Samani et al.
(166)Ho-EDTMP is a major therapeutic agent which is widely used in bone palliation therapy. In this study, a (166)Ho-EDTMP complex was prepared successfully using an in-house synthesized EDTMP ligand and (166)HoCl(3). Ho-166 chloride was ob...
Method development and validation of montelukast in human plasma by HPLC coupled with ESI-MS/MS: application to a bioequivalence study [0.03%]
人血浆中孟鲁司特的HPLC-ESI-MS/MS分析方法的建立与验证及其在生物等效性研究中的应用
Balasekhara Reddy Challa,Bahlul Z Awen,Babu Rao Chandu et al.
Balasekhara Reddy Challa et al.
A simple, sensitive, and specific LC-ESIâMS/MS method for quantification of Montelukast (MO) in human plasma using Montelukast-d(6) (MOD6) as an internal standard (IS) is discussed here. Chromatographic separation was performed on YMC-pack...
Christa Kletter
Christa Kletter
This overview reflects the extensive changes in the health care system which had significant effects on the apothecaryâs profession and education. In the 18(th) century Maria Theresia assigned Gerard van Swieten to modernize the medical cu...
Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid [0.03%]
含有羟基酸、β环糊精的氢溴酸伏宁三元捏合固体制备及体内外特性研究
Mona H Aburahma,Hanan M El-Laithy,Yassin El-Said Hamza
Mona H Aburahma
The demand for sublingual tablets has been growing during the previous decades especially for drugs with extensive hepatic first-pass metabolism. Vinpocetine, a widely used neurotropic agent, has low oral bioavailability due to its poor aqu...
Cyclosporine a-nanosuspension: formulation, characterization and in vivo comparison with a marketed formulation [0.03%]
环孢素A纳米悬液：配方、特征及与市售药物的在体比较研究
Mahendra Nakarani,Priyal Patel,Jayvadan Patel et al.
Mahendra Nakarani et al.
Cyclosporine A-nanosuspensions were prepared using zirconium oxide beads as a milling media, Poloxamer 407 as a stabilizer and distilled water as an aqueous medium using the Pearl Milling technique. The optimized formulation was characteriz...
Babatunde Akinlade,Amal A Elkordy,Ebtessam A Essa et al.
Babatunde Akinlade et al.
A liquisolid system has the ability to improve the dissolution properties of poorly water soluble drugs. Liquisolid compacts are flowing and compactable powdered forms of liquid medications. The aim of this study was to enhance the in vitro...
Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride [0.03%]
盐酸曲马多口腔控释生物粘附片的配方优化研究
Bhupinder Singh,Ashu Rani,Babita et al.
Bhupinder Singh et al.
The directly compressible floating-bioadhesive tablets of tramadol were formulated using varying amounts Carbopol 971P (CP) and hydroxy-propylmethyl cellulose (HPMC), along with other requisite excipients. In vitro drug release profile, flo...
Formulation and in vitro evaluation of rifampicin loaded porous microspheres [0.03%]
雷米封多孔微球的制备及体外评价研究
Satish Balakrishna Bhise,Avinash Bhanudas More,Rajkumar Malayandi
Satish Balakrishna Bhise
Rifampicin (RIF) is a major component in fixed dose combination therapy for the treatment of tuberculosis. RIF has low solubility and high permeability with high dose and hence it is classified as class II drug in Biopharmaceutical Classifi...
Traditional medicine in the pristine village of ProkoÅko Lake on Vranica Mountain, Bosnia and Herzegovina [0.03%]
波黑弗拉尼察山普罗科科湖畔原始村落的传统医药
Broza Aariä-Kundaliä,Elisabeth Fritz,Christoph Dobeå et al.
Broza Aariä-Kundaliä et al.
The results of an ethnobotanical study conducted in the pristine village of ProkoÅko Lake (Vranica Mountain, Bosnia and Herzegovina) in summer 2007 is presented. Informal interviews involving 12 informants known as âtraditional healersâ ...