Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride
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The directly compressible floating-bioadhesive tablets of tramadol were formulated using varying amounts Carbopol 971P (CP) and hydroxy-propylmethyl cellulose (HPMC), along with other requisite excipients. In vitro drug release profile, floatational characteri... ...
