Antibacterial Activity of Hen Egg White Lysozyme Denatured by Thermal and Chemical Treatments [0.03%]
热和化学处理变性的蛋清溶菌酶的抗菌活性研究
Rubén Vilcacundo,Pilar Méndez,Walter Reyes et al.
Rubén Vilcacundo et al.
The aim of this study was to increase the antibacterial spectrum of modified hen egg white lysozyme (HEWL) with thermal and chemical treatments against Gram-negative bacteria. The antibacterial activity of heat-denatured HEWL and chemical d...
Isothiochromenothiazoles-A Class of Fused Thiazolidinone Derivatives with Established Anticancer Activity That Inhibits Growth of Trypanosoma brucei brucei [0.03%]
异色クロモノチアゾール-抗白血病活性己確立的融合噻唑idine衍生物抑制Trypanosoma brucei brucei增殖
Anna Kryshchyshyn,Danylo Kaminskyy,Igor Nektegayev et al.
Anna Kryshchyshyn et al.
Recently, thiazolidinone derivatives have been widely studied as antiparasitic agents. Previous investigations showed that fused 4-thiazolidinone derivatives (especially thiopyranothiazoles) retain pharmacological activity of their syntheti...
NO-Donor Nitrosyl Iron Complex with 2-Aminophenolyl Ligand Induces Apoptosis and Inhibits NF-κB Function in HeLa Cells [0.03%]
带有2-氨基酚配体的NO供体亚硝基铁配合物能诱导HeLa细胞凋亡并抑制其NF-κB功能
Tatiana Stupina,Anastasia Balakina,Tatiana Kondrat&#x;eva et al.
Tatiana Stupina et al.
NO donating iron nitrosyl complex with 2-aminothiophenyl ligand (2-AmPh complex) was studied for its ability to cause cell death and affect nuclear factor kappa B (NF-κB) signaling. The complex inhibited viability of HeLa cells and induced...
Fadi G Saqallah,Wafaa M Hamed,Wamidh H Talib
Fadi G Saqallah
Mediterranean-native perennial plant Antirrhinum majus was scrutinized in this study for its antioxidant activity and its total phenolic content in order to test for the plant's wound-healing capability. The traditional uses of this plant t...
Potential Role of Microfibrillar-Associated Protein 4, Fibrotic Indices and Oxidative Stress in Hepatocellular Carcinoma [0.03%]
微纤丝相关蛋白4、纤维化指标和氧化应激在肝细胞癌的潜在作用
Mohamed M Salama,Manal M Nomir,Maryan W Fahmi et al.
Mohamed M Salama et al.
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide. In an attempt to understand some potential mechanisms of persistence and oncogenicity of Hepatitis C virus (HCV)-related HCC, microfibrillar-a...
Pharmacokinetic Enhancers (Boosters)-Escort for Drugs against Degrading Enzymes and Beyond [0.03%]
药代动力学增效剂(Booster)-降解酶作用下的药物护卫者及其更多功能
Jürgen Krauß,Franz Bracher
Jürgen Krauß
Pharmacokinetic enhancers (boosters) are compounds used in combination with a primary therapeutic agent (drug) and are not used for their direct effects on the disease but because they enhance or restore the activity of the primary agent. H...
Structure-Antibacterial Activity Relationships of N-Substituted-(d-/ l-Alaninyl) 1 H-1,2,3-Triazolylmethyl Oxazolidinones [0.03%]
N-取代-(D-/L-丙氨酰)-1H-1,2,3-三氮唑甲基恶唑烷酮的结构与抗菌活性关系研究
Oludotun Adebayo Phillips,Edet Ekpenyong Udo,Roselyn Jennifer D&#x;silva
Oludotun Adebayo Phillips
Bacterial resistance towards the existing class of antibacterial drugs continues to increase, posing a significant threat to the clinical usefulness of these drugs. These increasing and alarming rates of antibacterial resistance development...
Antifibrotic Activity and In Ovo Toxicity Study of Liver-Targeted Curcumin-Gold Nanoparticle [0.03%]
肝靶向姜黄素-金纳米颗粒的抗纤维化活性及在卵研究
Amirah Adlia,Ilham Tomagola,Sophi Damayanti et al.
Amirah Adlia et al.
Conjugation of curcumin and gold with green chemistry is an approach to improve the effectiveness of curcumin as anti-fibrosis. In this work, curcumin and gold were conjugated to deliver curcumin to the liver. Curcumin-gold nanoparticles (c...
In Vitro Antimicrobial Activity of Essential Oils from Sardinian Flora against Cutibacterium (Formerly Propionibacterium) acnes and Its Enhancement by Chitosan [0.03%]
壳聚糖增强的撒丁岛植物精油对Cutibacterium( formerl y Propionibacterium) acne s的体外抗菌活性
Claudia Juliano,Mauro Marchetti,Maria Luisa Pisu et al.
Claudia Juliano et al.
The in vitro antibacterial activity of some essential oils from Sardinian flora, both alone and in combination with chitosan, was investigated against a strain of Cutibacterium acnes, a bacterium involved in pathogenesis of acne. The compos...
Effect of Piperine on Skin Permeation of Curcumin from a Bacterially Derived Cellulose-Composite Double-Layer Membrane for Transdermal Curcumin Delivery [0.03%]
姜黄素-胡椒碱复合双层透皮给药膜的体外及离体评价研究
Chutima Jantarat,Pornpak Sirathanarun,Somruedee Boonmee et al.
Chutima Jantarat et al.
Curcumin is a naturally occurring substance with various pharmacological activities. It has not been developed as a drug because of its low bioavailability due to its low solubility and absorption. Piperine is a natural enhancer that is pop...