Comparative analysis of anti-MICA scFv affinities: Insights from three label-free biophysical methods and biological validation [0.03%]
Karen Toledo-Stuardo,Nicolás Fehring,Homero Gómez-Velasco et al.
Karen Toledo-Stuardo et al.
Antibody-antigen affinity is a key factor in the development of therapeutic antibodies, influencing candidate selection and their clinical efficacy. We used a combination of three label-free biophysical techniques: SPR, ITC, and fluorescenc...
Transition from fermentation to precision fermentation: Role in sustainable food system [0.03%]
从发酵到精准发酵：在可持续食品系统中的作用
Oluwatobi Victoria Obayomi,Adekunbi Adetola Malomo,Abiola Folakemi Olaniran et al.
Oluwatobi Victoria Obayomi et al.
Fermentation has been used for centuries to preserve foods and enhance their sensory, nutritional, medicinal, and commercial qualities, as demonstrated by products such as bread, beer, yogurt, and cheese. Since the 1970s, advances in geneti...
Development of anti-dengue virus D8 neutralizing monoclonal antibody production in Nicotiana benthamiana [0.03%]
利用烟草原生质体制备抗登革病毒D8中和单克隆抗体
Gunt Niyompun,Kaewta Rattanapisit,Janejira Jaratsittisin et al.
Gunt Niyompun et al.
Dengue is a life-threatening mosquito-borne viral disease ranging from mild symptoms to severe hemorrhagic fever. In this study, a recombinant anti-dengue D8 monoclonal antibody was produced in Nicotiana benthamiana and characterized for pr...
Double-layer microencapsulation of Lacticaseibacillus rhamnosus using sodium alginate and nano-mucilages of Qodume Shirazi and Camelina sativa for probiotic goat milk dessert [0.03%]
使用海藻酸钠和Qodume Shirazi及 camelina sativa 的纳米粘胶双重微包被乳双歧杆菌生产 probiotic 山羊奶甜品
Seyed Saeed Sekhavatizadeh,Neda Maftoonazad,Hadis Motashafi et al.
Seyed Saeed Sekhavatizadeh et al.
This study is the first to utilize nano-scale Qodume Shirazi seed mucilage (QSSM) and Camelina sativa seed mucilage (CSSM), individually and in combination, as natural wall materials for microencapsulation of Lacticaseibacillus rhamnosus (L...
Generation and characterization of a HEK293 cell line optimized for recombinant adeno-associated virus production [0.03%]
重组腺相关病毒产生的HEK293细胞系的构建与鉴定
Mélissa Vona,Iris Bodenmann,Marc-Antoine Perrenoud et al.
Mélissa Vona et al.
HEK293 is a preferred cellular platform to produce viral vectors including adeno-associated viruses (AAV). However, HEK293 cells were shown to be genomically unstable and many HEK293 cell lines having distinct genotypes and phenotypes have ...
Valorization of agricultural residues for bioplastic production by bacteria isolated from plastic dumpsites: Integrating waste streams into the circular bioeconomy [0.03%]
来源于塑料垃圾场的细菌生产生物塑料整合废物到循环经济中农作物残留物的增值
Olawale Sunday Olayiwola,Oladipo Oladiti Olaniyi,Elizabeth Odunmbaku et al.
Olawale Sunday Olayiwola et al.
Polyhydroxybutyrate (PHB) is a biodegradable polymer produced by bacteria under nutrient-limiting conditions, offering a sustainable alternative to petroleum plastics. This study investigated PHB production by bacterial isolates from plasti...
Exploring differential gene correlations in Arabidopsis thaliana for sustainable space farming [0.03%]
探索拟南芥基因相关性以实现可持续的空间农业
Federica D&#x;Annunzio,Giulia Fiscon,Federica Conte et al.
Federica D&#x;Annunzio et al.
The plans for sustained human presence on the Moon have increased interest in understanding the effects of lunar conditions on terrestrial biology. Plants play a vital role in space exploration, as they not only generate oxygen and remove c...
Bacillus altitudinis GG-22: A novel plant growth-promoting bacterium with beneficial agronomic properties [0.03%]
一株具有优良农艺性状的植物促生细菌 Bacillus altitudinis GG-22
Ana Falcón-Piñeiro,Alberto Baños,Eva M Molin et al.
Ana Falcón-Piñeiro et al.
Bacillus altitudinis GG-22, isolated from the phyllosphere of agricultural crops, has been identified as a promising biocontrol agent and plant growth-promoting bacterium with substantial potential in sustainable agriculture. In this study,...
Insulin Resistance, Anti-inflammatory, and Antioxidant In vitro Activity of Heterologously Expressed Arenin from Dryophytes arenicolor [0.03%]
来源于Dryophytes arenicolor的 Arenin 的异源表达及其体外胰岛素增敏、抗炎及抗氧化活性研究
Enrique Hidalgo-Vázquez,Marilena Antunes-Ricardo,Jesús Hernández-Pérez et al.
Enrique Hidalgo-Vázquez et al.
Amphibian-derived peptides are promising therapeutics for metabolic dysfunction, oxidative stress, and immune imbalance. We investigated arenin, a Kunitz-type peptide from Dryophytes arenicolor, produced heterologously in E. coli, for anti-...
Production and characterization of rNGFSP: a recombinant fusion immunogen eliciting dual anti-NGF and anti-Substance P therapeutic antibodies for Degenerative Joint Disease [0.03%]
用于制备同时抗NGF和抗物质P的治疗型双特异性抗体的重组融合免疫原rNGFSP的构建及鉴定
Valentina Varela,Monique Costa,Cecilia Maciel et al.
Valentina Varela et al.
Anti-NGF monoclonal antibodies have recently been approved for treating degenerative joint disease, including osteoarthritis pain, in dogs and cats. However, their widespread use is limited by high cost and the requirement for repeated inje...