Heterologous phasin expression in Rhodopseudomonas palustris CGA009 for bioplastic production from lignocellulosic biomass [0.03%]
红假单胞菌中异源phasins的表达用于生产生物塑料
Brandi Brown,Cheryl Immethun,Adil Alsiyabi et al.
Brandi Brown et al.
Rhodopseudomonas palustris CGA009 is a metabolically robust microbe that can utilize lignin breakdown products to produce polyhydroxyalkanoates (PHAs), biopolymers with the potential to replace conventional plastics. Our recent efforts sugg...
Overcoming glutamate auxotrophy in Escherichia coli itaconate overproducer by the Weimberg pathway [0.03%]
通过Weimberg途径克服谷氨酸营养缺陷以生产衣康酸菌株
Ken W Lu,Chris T Wang,Hengray Chang et al.
Ken W Lu et al.
Biosynthesis of itaconic acid occurs through decarboxylation of the TCA cycle intermediate cis-aconitate. Engineering of efficient itaconate producers often requires elimination of the highly active isocitrate dehydrogenase to conserve cis-...
Resveratrol production from several types of saccharide sources by a recombinant Scheffersomyces stipitis strain [0.03%]
几个重组Scheffersomyces stipitis菌株从几种糖源产生白藜芦醇
Yuma Kobayashi,Kentaro Inokuma,Mami Matsuda et al.
Yuma Kobayashi et al.
Resveratrol is a plant-derived aromatic compound with a wide range of beneficial properties including antioxidant and anti-aging effects. The resveratrol currently available on the market is predominantly extracted from certain plants such ...
Biosensor-based isolation of amino acid-producing Vibrio natriegens strains [0.03%]
基于生物传感器分离产氨基酸的盐生 vibrio 菌株
Roberto Giuseppe Stella,Philipp Baumann,Sophia Lorke et al.
Roberto Giuseppe Stella et al.
The marine bacterium Vibrio natriegens has recently been demonstrated to be a promising new host for molecular biology and next generation bioprocesses. V. natriegens is a Gram-negative, non-pathogenic slight-halophilic bacterium, with a hi...
Erratum regarding previously published articles in volumes 9, 10 and 11 [0.03%]
关于卷9、10和11中先前发表的文章的更正错误通知
[This corrects the article DOI: 10.1016/j.mec.2020.e00145.][This corrects the article DOI: 10.1016/j.mec.2019.e00096.][This corrects the article DOI: 10.1016/j.mec.2019.e00089.][This corrects the article DOI: 10.1016/j.mec.2019.e00120.][Thi...
Published Erratum
Metabolic engineering communications. 2021 Oct 28:13:e00186. DOI:10.1016/j.mec.2021.e00186 2021
Diversion of metabolic flux towards 5-deoxy(iso)flavonoid production via enzyme self-assembly in Escherichia coli [0.03%]
通过大肠杆菌中的酶自组装将代谢流转向5-去氧(异)黄烷生产
Jianhua Li,Fanglin Xu,Dongni Ji et al.
Jianhua Li et al.
5-Deoxy(iso)flavonoids are structural representatives of phenylpropanoid-derived compounds and play critical roles in plant ecophysiology. Recently, 5-deoxy(iso)flavonoids gained significant interest due to their potential applications as p...
Elimination of aromatic fusel alcohols as by-products of Saccharomyces cerevisiae strains engineered for phenylpropanoid production by 2-oxo-acid decarboxylase replacement [0.03%]
通过更换2-氧酸脱羧酶来消除酿酒酵母菌株在合成酚丙烷类化合物过程中产生的芳香杂醇副产品
Else-Jasmijn Hassing,Joran Buijs,Nikki Blankerts et al.
Else-Jasmijn Hassing et al.
Engineered strains of the yeast Saccharomyces cerevisiae are intensively studied as production platforms for aromatic compounds such as hydroxycinnamic acids, stilbenoids and flavonoids. Heterologous pathways for production of these compoun...
Transport engineering for improving the production and secretion of valuable alkaloids in Escherichia coli [0.03%]
通过运载工具工程提高大肠杆菌中珍贵生物碱产量和分泌量
Yasuyuki Yamada,Miya Urui,Hidehiro Oki et al.
Yasuyuki Yamada et al.
Microorganisms can be metabolically engineered to produce specialized plant metabolites. However, these methods are limited by low productivity and intracellular accumulation of metabolites. We sought to use transport engineering for produc...
Identification of novel inhibitory metabolites and impact verification on growth and protein synthesis in mammalian cells [0.03%]
新型抑制性代谢物的识别及其对哺乳动物细胞生长和蛋白质合成影响的验证
Bingyu Kuang,Venkata Gayatri Dhara,Duc Hoang et al.
Bingyu Kuang et al.
Mammalian cells consume large amount of nutrients during growth and production. However, endogenous metabolic inefficiencies often prevent cells to fully utilize nutrients to support growth and protein production. Instead, significant fract...
Metabolic engineering of Synechocystis sp. PCC 6803 for the photoproduction of the sesquiterpene valencene [0.03%]
代谢工程改造集胞藻6803产香叶烯
Maximilian Dietsch,Anna Behle,Philipp Westhoff et al.
Maximilian Dietsch et al.
Cyanobacteria are extremely adaptable, fast-growing, solar-powered cell factories that, like plants, are able to convert carbon dioxide into sugar and oxygen and thereby produce a large number of important compounds. Due to their unique pho...