A hidden threat: a case of relapsed disseminated Mycobacterium abscessus infection and its therapeutic challenges [0.03%]
隐匿的威胁——一例广泛分布的恶臭分支杆菌复发感染及其治疗挑战的病例报告
Katherine Grace Egan,Lisa Duffy,Catherine Fleming et al.
Katherine Grace Egan et al.
Mycobacterium abscessus (M. abscessus) is a rapidly growing nontuberculous mycobacterium (NTM). We present the case of a 57-year-old female on immunosuppressive therapy for polymyalgia rheumatica (PMR) who developed disseminated M. abscessu...
Bone transport in the management of fracture-related infection: current concepts and innovations [0.03%]
骨搬运在骨折相关感染治疗中的应用：当前概念与创新技术
Willem-Jan Metsemakers,Austin T Fragomen,Mario Morgenstern et al.
Willem-Jan Metsemakers et al.
Despite advances in musculoskeletal trauma care, segmental bone loss remains a major clinical challenge. A substantial proportion of these cases are associated with fracture-related infection (FRI), which fundamentally alters the biological...
Combined analysis of host immune response, biofilm genes, and 16S rRNA detection in fracture-related infection: an observational cohort study [0.03%]
结合宿主免疫反应、生物膜基因和16S rDNA检测的联合分析：一项队列研究
Melissa Depypere,Jonathan Sliepen,Jolien Onsea et al.
Melissa Depypere et al.
Fracture-related infection (FRI) is a serious complication in orthopaedic trauma that can lead to delayed union, nonunion, and poor clinical outcomes. A better understanding of the host immune response may provide valuable insights into the...
Advancing diagnostics in suspected periprosthetic joint infections using synthetic synovial fluid and microcalorimetry [0.03%]
采用人工滑膜液和微热量计技术提高假体周围关节感染的诊断水平
Amber De Bleeckere,Jeroen Neyt,Jasper Van Heuverswyn et al.
Amber De Bleeckere et al.
Rapid and accurate pathogen detection is essential for effective management of periprosthetic joint infections (PJIs), yet conventional culturing (CC) often yields false-negative results and requires prolonged incubation times. In the prese...
Malnutrition affects infection rates and quality of life in patients undergoing primary hip and knee arthroplasty: a retrospective study [0.03%]
营养不良影响初次髋膝关节置换患者的感染率和生活质量：回顾性研究
Domenico De Mauro,Chiara Comisi,Valeria Maccauro et al.
Domenico De Mauro et al.
Background: Although malnutrition is globally associated with incremental morbidity, mortality, and cost, there has been a fundamental lack of consensus on diagnostic criteria for application in clinical settings. The study aims were (i) to...
Septic arthritis and prosthetic joint infections: microbial spectrum and evolving resistance patterns [0.03%]
化脓性关节炎与人工关节感染的微生物分布及耐药模式的变化趋势
Merve Gürler,Füsun Kırca,Bedia Dinç
Merve Gürler
Background: Septic arthritis (SA) and prosthetic joint infection (PJI) are severe musculoskeletal emergencies associated with rapid joint destruction, functional disability, and high mortality. Accurate microbiological diagnosis remains cha...
Treatment of periprosthetic joint infection - outcomes following algorithm-guided treatment at a multidisciplinary referral centre [0.03%]
人工关节周围感染的治疗：多学科转诊中心指导下的治疗算法的效果分析
Christian Merz,Jan Klaas,Rik Osinga et al.
Christian Merz et al.
Introduction: This study evaluated early treatment outcomes and the management of complications in patients with periprosthetic joint infection (PJI) of the hip and knee treated at a specialized centre using an algorithm-guided multidiscipl...
Safety of locally applied antibiotics in orthopaedic trauma surgery: descriptive results from a prospective cohort study [0.03%]
局部应用抗生素的安全性：一项前瞻性队列研究的描述性结果
Niels Vanvelk,Esther M M Van Lieshout,Leendert H T Nugteren et al.
Niels Vanvelk et al.
Antibiotic therapy holds an integral role in the prevention and treatment of fracture-related infection (FRI). Because local concentrations after systemic administration are limited by the potential for side effects, the local application o...
How much are we willing to do for the ones we love - impact on caregivers of patients suffering from periprosthetic joint infections: a qualitative study [0.03%]
为了爱的人我们可以付出多少——人工关节置换术后感染患者的照料者的影响：一项定性研究
Franz-Joseph Dally,Franziska Prüßner,Frederic Bludau et al.
Franz-Joseph Dally et al.
Introduction: We aimed to identify and explore the psychological and physical strains that caregivers of patients suffering from a periprosthetic joint infection (PJI) experience. Methods: Twenty-four qualitative semi-structured interviews ...
High failure rate in Pseudomonas aeruginosa-associated periprosthetic hip and knee joint infections [0.03%]
铜绿假单胞菌所致的人工髋关节和膝关节置换术后感染的高失败率
Ece Akcicek,Jennyfer A Mitterer,Veronika Achatz et al.
Ece Akcicek et al.
Introduction: Pseudomonas aeruginosa is one of the most common Gram-negative (GN) pathogens in periprosthetic joint infections (PJIs). However, not many data are available on them. This study aimed to evaluate the prevalence of P. aeruginos...