Timing from admission to debridement, antibiotic, and implant retention (DAIR) affects mortality risk in total hip prosthetic joint infections [0.03%]
术后及时进行清创、使用抗生素和保留假体(DAIR)可降低全髋关节置换术感染患者的死亡风险
Jack Legler,Samuel Morgan,Paul Beaulé et al.
Jack Legler et al.
Introduction: Recent work in total knee arthroplasty (TKA) prosthetic joint infection (PJI) suggests that timing from hospital admission to DAIR (debridement, antibiotic, and implant retention) is a modifiable risk factor influencing treatm...
Bromelain and N-acetylcysteine (BromAc) as novel adjunctive therapy for prosthetic joint infection: a narrative review [0.03%]
菠萝蛋白酶和N-乙酰半胱氨酸(BromAc)作为关节置换术后感染的新型辅助治疗：综述型研究
Brendan Parnell,David Morris
Brendan Parnell
Background: Prosthetic joint infection (PJI) complicates 0.5 %-2.0 % of total joint arthroplasties and remains the leading cause of implant failure. Bacterial biofilm confers marked antimicrobial resistance, and current strategies, includin...
Rapid molecular culture versus conventional culture for periprosthetic joint infection: diagnostic performance and clinical relevance [0.03%]
快速分子培养与传统培养在关节置换术后感染中的诊断性能及临床相关性比较研究
Elizabeth Morreel,Paul Savelkoul,Inge van Loo
Elizabeth Morreel
Introduction: Periprosthetic joint infection (PJI) remains a major complication of joint arthroplasty, requiring rapid and accurate pathogen identification to guide appropriate antimicrobial therapy. Conventional culture is limited by prolo...
Sonication fluid cultures enhance pathogen identification in fracture-related-infection (FRI) [0.03%]
声波震荡液体培养可提高骨折相关感染中病原体的鉴定率
Anas Zouitni,Erlangga Yusuf,Jakob van Oldenrijk et al.
Anas Zouitni et al.
Background: Sonication fluid culture (SFC) of osteosynthesis material may be a valuable adjunct tool to diagnose fracture-related infection (FRI). This study aims to evaluate the added diagnostic value of SFC as a diagnostic tool. The diagn...
Management and outcomes of culture-negative periprosthetic joint infection: a systematic review and meta-analysis [0.03%]
无病原体(periprosthetic关节感染的管理及预后：系统回顾及meta分析）
Farzad Pourghazi,Seyed Mohammad Amin Alavi,Takahiro Matsuo et al.
Farzad Pourghazi et al.
Introduction: Culture-negative periprosthetic joint infection (CN-PJI) remains a major diagnostic and therapeutic challenge because antimicrobial and surgical management are often empirical. Methods: We performed a systematic review and met...
Management of fracture-related infection in low-resource settings in Africa: recommendations and guidelines from an international expert group [0.03%]
非洲低资源环境下骨折相关感染的管理：国际专家小组的建议和指南
Loïc Fonkoué,Elizabeth K Tissingh,Leonard C Marais et al.
Loïc Fonkoué et al.
Background: Fracture-related infection (FRI) represents one of the most challenging complications in trauma care and disproportionately affects patients in low-resource settings, where diagnostic capacity, surgical infrastructure, and acces...
Literature review and case report on the use of rezafungin for spondylodiscitis in an outpatient parenteral antimicrobial therapy (OPAT) setting [0.03%]
门诊抗生素治疗(OPAT)中雷扎fungin治疗脊椎盘炎的文献回顾与病例报告
Alexander J Richards,Ammara Asif,Monica Ivan et al.
Alexander J Richards et al.
Bone and joint infections secondary to Candida species are associated with high morbidity and mortality, requiring extended courses of antifungal therapy, with parenteral medications being first-line therapy. The reported use of antifungals...
Changes in systemic immune-inflammation index predict periprosthetic joint infection after hemiarthroplasty in elderly patients [0.03%]
系统免疫炎症指数变化可预测人工关节置换术后的假体周围感染
Emre Bilgin,Onur Gultekin,Murat Kilic et al.
Emre Bilgin et al.
Background: Periprosthetic joint infection (PJI) remains a devastating complication after hemiarthroplasty in elderly patients with femoral neck fractures. Early identification of high-risk patients is important. The systemic immune-inflamm...
Integrating molecular and conventional diagnostics in native vertebral osteomyelitis: a narrative review [0.03%]
分子和传统诊断在原发性椎骨骨髓炎中的应用：综述文章
Farzad Pourghazi,Omar Mahmoud,Francesco Petri et al.
Farzad Pourghazi et al.
Native vertebral osteomyelitis (NVO) remains a diagnostic challenge due to its non-specific presentation and the limited sensitivity of culture-based methods. Blood cultures and image-guided biopsies are considered the diagnostic standards,...
Neutrophil extracellular trap (NET)-related index as an indicator of periprosthetic joint infection [0.03%]
中性粒细胞胞外陷阱相关指数可作为假体周围关节感染的标志物
Tingrun Cui,Yongjian Liang,Zeyu Feng et al.
Tingrun Cui et al.
Background: Periprosthetic joint infection (PJI) is a devastating complication of arthroplasty and is difficult to diagnose accurately. This study aims to explore the value of neutrophil extracellular traps in synovial fluid (SF-NETs, web-l...