Hierarchical Integration of MOF-Based Nanoplatforms with Electrospun Nanofiber Scaffolds for Spatiotemporally Sustained Diabetic Wound Healing [0.03%]
基于MOF的纳米平台与静电纺纳米纤维支架分层整合用于时空可控的糖尿病伤口治疗
Qizhen Wang,Jia Xu,YueHao Xu et al.
Qizhen Wang et al.
Currently, diabetic wound dressings continue to exhibit various limitations, hindering their ability to effectively respond to the dynamic and complex microenvironment of diabetic wounds. Particularly, significant challenges remain in devel...
Pump-Free Unidirectional Vertical Centrifugal Microfluidic Platform for Dynamic 3D Tumor Cluster Culture and Functional Drug Screening [0.03%]
一种用于动态三维肿瘤团簇培养和功能性药物筛选的无泵微流控平台
Ke Ning,Yuanyuan Xie,Xiaoyan Yang et al.
Ke Ning et al.
Recapitulating the dynamic microenvironment is essential for advanced 3D cell culture and reliable drug testing, yet conventional static platforms lack physiologically relevant fluid dynamics. Here, a pump-free vertical dual-circulation cen...
Precisely Targeting Cardiac Remodeling Nanomachine for Restarting Healthy Heartbeat [0.03%]
精准靶向心脏重构纳米机器以重启健康心跳
Weixin Wang,Rui Gao,Lin Zhang et al.
Weixin Wang et al.
Atrial fibrillation (AF) is a common arrhythmia that can cause serious symptoms and affect the quality of life of patients. Therefore, the treatment of AF has always faced challenges in the medical field. Here, Zn@Mg@MSNs@PEG nanosphere-bas...
Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia [0.03%]
天然甜味剂stevioside基质的溶离型microneedles使治疗雄激素性脱发的药物米诺地尔溶解
Junying Zhang,Tianyu Shao,Hailiang Li et al.
Junying Zhang et al.
Androgenetic alopecia (AGA) is a prevalent form of non-scarring hair loss. Standard treatments, which include minoxidil (MXD) tincture and foam, face challenges due to MXD's water insolubility and poor skin permeability. The result is exten...
Emerging Applications and Challenges in SPR-Based Biosensors for Non-Invasive Quality Assessment of Wharton's Jelly-Derived Mesenchymal Stem Cells (WJ-MSCs) via Secretome Analysis [0.03%]
基于SPR的生物传感器在胎盘华通胶间充质干细胞分泌组分析中的新兴应用及挑战以实现非侵入性质量评估
Abilashinee Govindasamy,Wan Safwani Wan Kamarul Zaman,Salmah Karman et al.
Abilashinee Govindasamy et al.
Mesenchymal stem cells (MSCs) have gained widespread attention for their regenerative and immunomodulatory potential, primarily mediated through their secretome. Among various MSC sources, Wharton's Jelly-derived MSCs (WJ-MSCs) are emerging...
Formulating Smart All-in-One Chitosan Hydrogel for High Performance Wound Dressing [0.03%]
用于高性能创面敷料的智能多功能壳聚糖水凝胶制备
Chia-Chi Lin,Andi Magattang Gafur Muchlis,Ren-Jei Chung et al.
Chia-Chi Lin et al.
The poor mechanical and film formation properties of chitosan hydrogel limit its application as a wound dressing. To solve this shortcoming, chitosan-graft-poly(N-isopropyl acrylamide) (PNIPAAm) and crosslinked with polyvinyl alcohol/polyvi...
ROS-Triggered Microgels for Programmable Drug Release in Volumetric Muscle Loss Repair [0.03%]
基于ROS响应的微凝胶用于体积性肌肉缺损修复中的可编程药物释放
Seungjun Lee,Goeun Choe,Junghyun Kim et al.
Seungjun Lee et al.
Volumetric muscle loss (VML), frequently resulting from traumatic or surgical damage, causes significant muscle mass depletion and fibrosis, and presents major challenges to effective regeneration. In this study, reduced graphene-containing...
Photothermally Activated Pyroelectric Enhanced Self-Powered Wound Dressing: Breaking Through the Limitations of Interfacial Impedance to Achieve Efficient Electrical Stimulation for Wound Repair [0.03%]
光热激活的焦电增强型自供电创面敷料：突破界面阻抗限制实现高效伤口修复用电信号刺激
Yani Sun,Yufei Tang,Cuihong Sheng et al.
Yani Sun et al.
The mismatch between interfacial impedance at the hydrogel-electrical stimulation layer interface in conventional double-layer self-adhesive electrical stimulation wound dressings remains a critical challenge, limiting charge transfer effic...
Thermodynamic Delivery of Trehalose into Extracellular Vesicles for Enhanced Lyophilization [0.03%]
用于改善冷冻干燥的外泌体中海藻糖的动力学递送
Tian Wang,Ying Fu,Bangrui Yu et al.
Tian Wang et al.
Extracellular vesicles (EVs) hold great potential as therapeutic agents and drug carriers. Conventionally, EVs are cryopreserved at ultra-low temperatures, with substantial cryoinjury associated with the freeze/thaw cycle. Lyophilization ha...
Correction to "The Past, Present, and Future of Tubular Melt Electrowritten Constructs to Mimic Small Diameter Blood Vessels - A Stable Process?" [0.03%]
关于“用于模拟小型血管的管状熔融电纺构造的过去、现在和未来——一个稳定的过程？”一文中错误的更正
Published Erratum
Advanced healthcare materials. 2025 Oct 5:e04248. DOI:10.1002/adhm.202504248 2025