Neurofilament Light Chain and Differentiation of Behavioral Variant Frontotemporal Dementia From Psychiatric Disorders: A Systematic Review [0.03%]
神经丝轻链和行为变异型额颞叶痴呆与精神疾病鉴别：系统性综述
Dimitry S Davydow,Morgan Brasfield,Christopher B Morrow et al.
Dimitry S Davydow et al.
Importance: Behavioral variant frontotemporal dementia (bvFTD), the most common subtype of FTD, is a leading form of early-onset dementia worldwide. Accurate and timely diagnosis of bvFTD is frequently delayed due to symp...
High-Intensity Exercise and Hippocampal Integrity in Adults With Cannabis Use Disorder: A Randomized Clinical Trial [0.03%]
高强度锻炼对大麻使用障碍成人海马结构的影响：随机临床试验
Karyn E Richardson,Chao Suo,Lucy Albertella et al.
Karyn E Richardson et al.
Importance: Cannabis is the most commonly used illicit drug, with 10% to 30% of regular users developing cannabis use disorder (CUD), a condition linked to altered hippocampal integrity. Evidence suggests high-intensity i...
Josh Nguyen,Dominic B Dwyer,Barnaby Nelson et al.
Josh Nguyen et al.
ANK3 as a Novel Genetic Biomarker for Liafensine in Treatment-Resistant Depression: The ENLIGHTEN Randomized Clinical Trial [0.03%]
ANK3作为难治性抑郁症对联芬辛治疗反应的新型遗传生物标志物：ENLIGHTEN随机临床试验
Gang Wang,Mario Aguado,Matthew A Spear et al.
Gang Wang et al.
Importance: This study represents a first successful use of a genetic biomarker to select potential responders in a prospective study in psychiatry. Liafensine, a triple reuptake inhibitor, may become a new precision medi...
Semaglutide Treatment of Antipsychotic-Treated Patients With Schizophrenia, Prediabetes, and Obesity: The HISTORI Randomized Clinical Trial [0.03%]
利拉鲁肽治疗接受抗精神病药治疗的精神分裂症、糖尿病前期和肥胖患者的疗效：HISTORI随机临床试验
Ashok A Ganeshalingam,Nicolai Uhrenholt,Sidse Arnfred et al.
Ashok A Ganeshalingam et al.
Importance: Patients with schizophrenia have reduced life expectancy due to cardiovascular disease and obesity-related type 2 diabetes, exacerbated by second-generation antipsychotic (SGA) medication. Existing interventio...
Occurrence of Psychosis and Bipolar Disorder in Individuals With Attention-Deficit/Hyperactivity Disorder Treated With Stimulants: A Systematic Review and Meta-Analysis [0.03%]
注意缺陷多动障碍伴精神疾病和双相情感障碍的发病：系统评价和 meta 分析
Gonzalo Salazar de Pablo,Claudia Aymerich,Juan Pablo Chart-Pascual et al.
Gonzalo Salazar de Pablo et al.
Importance: Individuals with attention-deficit/hyperactivity disorder (ADHD) may present with psychosis or bipolar disorder (BD) following treatment with stimulants. The extent to which this occurs is currently unclear. ...
Polygenic Contributions to Lithium Augmentation Outcomes in Unipolar Depression [0.03%]
多基因对单相抑郁锂剂增效的贡献
Julia Kraft,Pichit Buspavanich,Alice Braun et al.
Julia Kraft et al.
Importance: Lithium augmentation is an effective treatment for patients with major depression after inadequate antidepressant response, but therapeutic outcomes vary considerably between individuals. Molecular studies may...
Antipsychotic Drugs and Dysregulated Glucose Homeostasis: A Systematic Review and Meta-Analysis [0.03%]
抗精神病药物与糖代谢紊乱：系统评价和荟萃分析
Emily C C Smith,Sri Mahavir Agarwal,Kristoffer J Panganiban et al.
Emily C C Smith et al.
Importance: Antipsychotic drug (AP)-induced glucose homeostasis changes are often attributed to AP-induced weight gain. Nevertheless, dysregulated glucose control can occur independently of weight gain. ...
Behavioral Activation for Perinatal Suicide Ideation: Secondary Analysis of a Noninferiority Randomized Clinical Trial [0.03%]
基于围产期自杀意念的行为激活：非劣效性随机临床试验的二次分析
Parisa R Kaliush,Nicolette C Molina,Tara S Berenbaum et al.
Parisa R Kaliush et al.
Importance: Suicide is a leading cause of maternal postpartum death. Evidence-based interventions are needed. Objective: To determine w...
Florian Naudet,Ioana A Cristea,Andre Gillibert
Florian Naudet