Regional Specificity of Cortical Layer 3 Dendritic Spine Deficits in Schizophrenia [0.03%]
精神分裂症患者大脑皮层第3层树突棘缺陷的环区特异性研究
Kenneth N Fish,Robert A Sweet,Matthew L MacDonald et al.
Kenneth N Fish et al.
Importance: Schizophrenia (SZ) is characterized by deficits in visual-spatial working memory, a function dependent on a distributed cortical network that includes nodes in the primary visual (V1), posterior parietal (PPC)...
New Reduced Drinking Goals in Alcohol Pharmacotherapy Trials-A Novel Public-Private Effort and FDA Approval Process [0.03%]
酒精药物治疗试验中的新型减量目标及产学研合作和FDA的审批流程
Raymond F Anton,Stephanie S O&#x;Malley,Karl Mann et al.
Raymond F Anton et al.
Reductions in World Health Organization Risk Drinking Levels as a Primary Efficacy End Point for Alcohol Clinical Trials: A Review [0.03%]
世界卫生组织饮酒危险水平降低作为酒精临床试验主要疗效终点的有效性综述
Katie Witkiewitz,Raymond F Anton,Stephanie S O&#x;Malley et al.
Katie Witkiewitz et al.
Importance: Alcohol use disorder (AUD) is a highly prevalent and costly psychiatric disorder. Abstinence has been considered the optimal outcome of treatment for AUD. Yet, most individuals with AUD do not seek treatment b...
National Trends in Inpatient Psychiatric Bed Supply, 2011 to 2023 [0.03%]
2011至2023年美国住院精神病床供应量的全国趋势
Karen Shen,Mark Olfson,Adam Sacarny
Karen Shen
Neurofilament Light Chain and Differentiation of Behavioral Variant Frontotemporal Dementia From Psychiatric Disorders: A Systematic Review [0.03%]
神经丝轻链和行为变异型额颞叶痴呆与精神疾病鉴别：系统性综述
Dimitry S Davydow,Morgan Brasfield,Christopher B Morrow et al.
Dimitry S Davydow et al.
Importance: Behavioral variant frontotemporal dementia (bvFTD), the most common subtype of FTD, is a leading form of early-onset dementia worldwide. Accurate and timely diagnosis of bvFTD is frequently delayed due to symp...
High-Intensity Exercise and Hippocampal Integrity in Adults With Cannabis Use Disorder: A Randomized Clinical Trial [0.03%]
高强度锻炼对大麻使用障碍成人海马结构的影响：随机临床试验
Karyn E Richardson,Chao Suo,Lucy Albertella et al.
Karyn E Richardson et al.
Importance: Cannabis is the most commonly used illicit drug, with 10% to 30% of regular users developing cannabis use disorder (CUD), a condition linked to altered hippocampal integrity. Evidence suggests high-intensity i...
Josh Nguyen,Dominic B Dwyer,Barnaby Nelson et al.
Josh Nguyen et al.
ANK3 as a Novel Genetic Biomarker for Liafensine in Treatment-Resistant Depression: The ENLIGHTEN Randomized Clinical Trial [0.03%]
ANK3作为难治性抑郁症对联芬辛治疗反应的新型遗传生物标志物：ENLIGHTEN随机临床试验
Gang Wang,Mario Aguado,Matthew A Spear et al.
Gang Wang et al.
Importance: This study represents a first successful use of a genetic biomarker to select potential responders in a prospective study in psychiatry. Liafensine, a triple reuptake inhibitor, may become a new precision medi...
Semaglutide Treatment of Antipsychotic-Treated Patients With Schizophrenia, Prediabetes, and Obesity: The HISTORI Randomized Clinical Trial [0.03%]
利拉鲁肽治疗接受抗精神病药治疗的精神分裂症、糖尿病前期和肥胖患者的疗效：HISTORI随机临床试验
Ashok A Ganeshalingam,Nicolai Uhrenholt,Sidse Arnfred et al.
Ashok A Ganeshalingam et al.
Importance: Patients with schizophrenia have reduced life expectancy due to cardiovascular disease and obesity-related type 2 diabetes, exacerbated by second-generation antipsychotic (SGA) medication. Existing interventio...
Occurrence of Psychosis and Bipolar Disorder in Individuals With Attention-Deficit/Hyperactivity Disorder Treated With Stimulants: A Systematic Review and Meta-Analysis [0.03%]
注意缺陷多动障碍伴精神疾病和双相情感障碍的发病：系统评价和 meta 分析
Gonzalo Salazar de Pablo,Claudia Aymerich,Juan Pablo Chart-Pascual et al.
Gonzalo Salazar de Pablo et al.
Importance: Individuals with attention-deficit/hyperactivity disorder (ADHD) may present with psychosis or bipolar disorder (BD) following treatment with stimulants. The extent to which this occurs is currently unclear. ...