Semaglutide Treatment of Antipsychotic-Treated Patients With Schizophrenia, Prediabetes, and Obesity: The HISTORI Randomized Clinical Trial [0.03%]
利拉鲁肽治疗接受抗精神病药治疗的精神分裂症、糖尿病前期和肥胖患者的疗效:HISTORI随机临床试验
Ashok A Ganeshalingam,Nicolai Uhrenholt,Sidse Arnfred et al.
Ashok A Ganeshalingam et al.
Importance: Patients with schizophrenia have reduced life expectancy due to cardiovascular disease and obesity-related type 2 diabetes, exacerbated by second-generation antipsychotic (SGA) medication. Existing interventio...
Occurrence of Psychosis and Bipolar Disorder in Individuals With Attention-Deficit/Hyperactivity Disorder Treated With Stimulants: A Systematic Review and Meta-Analysis [0.03%]
注意缺陷多动障碍伴精神疾病和双相情感障碍的发病:系统评价和 meta 分析
Gonzalo Salazar de Pablo,Claudia Aymerich,Juan Pablo Chart-Pascual et al.
Gonzalo Salazar de Pablo et al.
Importance: Individuals with attention-deficit/hyperactivity disorder (ADHD) may present with psychosis or bipolar disorder (BD) following treatment with stimulants. The extent to which this occurs is currently unclear. ...
Polygenic Contributions to Lithium Augmentation Outcomes in Unipolar Depression [0.03%]
多基因对单相抑郁锂剂增效的贡献
Julia Kraft,Pichit Buspavanich,Alice Braun et al.
Julia Kraft et al.
Importance: Lithium augmentation is an effective treatment for patients with major depression after inadequate antidepressant response, but therapeutic outcomes vary considerably between individuals. Molecular studies may...
Antipsychotic Drugs and Dysregulated Glucose Homeostasis: A Systematic Review and Meta-Analysis [0.03%]
抗精神病药物与糖代谢紊乱:系统评价和荟萃分析
Emily C C Smith,Sri Mahavir Agarwal,Kristoffer J Panganiban et al.
Emily C C Smith et al.
Importance: Antipsychotic drug (AP)-induced glucose homeostasis changes are often attributed to AP-induced weight gain. Nevertheless, dysregulated glucose control can occur independently of weight gain. ...
Behavioral Activation for Perinatal Suicide Ideation: Secondary Analysis of a Noninferiority Randomized Clinical Trial [0.03%]
基于围产期自杀意念的行为激活:非劣效性随机临床试验的二次分析
Parisa R Kaliush,Nicolette C Molina,Tara S Berenbaum et al.
Parisa R Kaliush et al.
Importance: Suicide is a leading cause of maternal postpartum death. Evidence-based interventions are needed. Objective: To determine w...
Florian Naudet,Ioana A Cristea,Andre Gillibert
Florian Naudet
Samuel T Wilkinson,Taeho Greg Rhee
Samuel T Wilkinson
Collaborative Care for Opioid Use Disorder in Primary Care: A Hybrid Type 2 Cluster Randomized Clinical Trial [0.03%]
初级保健中的协作性阿片类药物使用障碍照护模式:混合Ⅱ型群随机临床试验
John C Fortney,Anna D Ratzliff,Brittany E Blanchard et al.
John C Fortney et al.
Importance: The criterion-standard treatment for opioid use disorder (OUD) is medications for OUD (MOUD). However, less than a quarter of people with OUD receive MOUD. The collaborative care model (CCM) is an evidence-bas...
Antonio Del Casale,Robert Preissner,Maurizio Simmaco
Antonio Del Casale
Psychiatric and Substance Use Disorders After Nonfatal Firearm Injury [0.03%]
枪械伤害的幸存者中精神疾病和物质使用障碍的患病率及其危险因素:一项基于人群的队列研究
Katherine A Koh,Mia Giuriato,Chana A Sacks et al.
Katherine A Koh et al.