Psychedelic Therapy vs Antidepressants for the Treatment of Depression Under Equal Unblinding Conditions: A Systematic Review and Meta-Analysis [0.03%]
Zachary J Williams,Hannah Barnett,Balázs Szigeti
Zachary J Williams
Importance: Psychedelic-assisted therapy (PAT) trials have high levels of functional unblinding, which biases results when comparing PAT with blinded interventions. Because PAT is effectively always open label, treatment ...
James I Hudson,Harrison G Pope Jr
James I Hudson
The Year in Review, 2025 [0.03%]
Dost Öngür
Dost Öngür
Roger D Weiss,Edward V Nunes,Scott E Provost
Roger D Weiss
Transdiagnostic Patterns of Grip Strength in Schizophrenia, Current Depression, and Remitted Depression [0.03%]
Sofie von Känel,Anastasia Pavlidou,Niluja Nadesalingam et al.
Sofie von Känel et al.
Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression: The EPISODE Randomized Clinical Trial [0.03%]
Lea J Mertens,Michael Koslowski,Felix Betzler et al.
Lea J Mertens et al.
Importance: Psilocybin shows promise in treating depression, although limitations of previous research warrant further research. Objective: ...
Eiko I Fried
Eiko I Fried
Importance: Psychiatric classification faces longstanding challenges, including heterogeneous diagnostic categories, high comorbidity rates, limited interrater reliability, and modest clinical utility. Successive revision...
Geert Dom,Cecile Hanon,Andrea Fiorillo et al.
Geert Dom et al.
Housing Displacement, Employment Disruption, and Mental Health After the 2023 Maui Wildfires [0.03%]
2023年毛伊岛野火后的住房流离、就业中断与心理健康问题
Ruben Juarez,Binh Le,Christopher Knightsbridge et al.
Ruben Juarez et al.
Importance: Climate-related disasters are escalating in frequency and severity, yet their population-level mental health impacts-especially in racially and ethnically diverse and geographically isolated settings-remain po...
Clozapine After 1 Failed Antipsychotic Drug Trial in First-Episode Psychosis: A Randomized Clinical Trial [0.03%]
首发精神病一种抗精神病药物治疗无效后的氯氮平临床试验研究
Xuan Li,Chang Lu,Zhaolin Zhai et al.
Xuan Li et al.
Importance: There is an urgent need for algorithm trials that address treatment steps in schizophrenia sequentially. Moreover, there is a debate about whether clozapine should be used after 1 failed antipsychotic drug tri...