Suicide and Self-Harm Events With GLP-1 Receptor Agonists in Adults With Diabetes or Obesity: A Systematic Review and Meta-Analysis [0.03%]
GLP-1受体激动剂在糖尿病或肥胖成人中的自杀与自伤行为的系统评价和荟萃分析
Pouya Ebrahimi,Juan Carlos Batlle,Aryan Ayati et al.
Pouya Ebrahimi et al.
Importance: Bariatric surgery, once the criterion standard in obesity treatment, has a small but concerning association with increased suicidality. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs), originally develop...
Prescription Stimulant Use, Misuse, and Use Disorder Among US Adults Aged 18 to 64 Years [0.03%]
美国18至64岁成人中处方刺激药的使用、滥用及成瘾情况
Beth Han,Christopher M Jones,Nora D Volkow et al.
Beth Han et al.
Importance: Stimulants are increasingly prescribed for US adults. Whether such prescribing is associated with misuse and prescription stimulant use disorder (PSUD) is less understood. ...
Dost Öngür
Dost Öngür
Safety and Efficacy of Repeated Low-Dose LSD for ADHD Treatment in Adults: A Randomized Clinical Trial [0.03%]
成人ADHD治疗中重复小剂量LSD的安全性和有效性：一项随机临床试验
Lorenz Mueller,Joyce Santos de Jesus,Yasmin Schmid et al.
Lorenz Mueller et al.
Importance: Microdosing psychedelics, including lysergic acid diethylamide (LSD), has gained attention for its potential benefits in several psychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD)...
Maternal Inflammatory Proteins in Pregnancy and Neurodevelopmental Disorders at Age 10 Years [0.03%]
怀孕期间的母体炎症蛋白和孩子10岁时的神经发育障碍的关系
Tingting Wang,Parisa Mohammadzadeh,Jens Richardt Møllegaard Jepsen et al.
Tingting Wang et al.
Importance: Maternal inflammation during pregnancy has been associated with an increased risk of neurodevelopmental disorders (NDDs), such as attention-deficit/hyperactivity disorder (ADHD) and autism, and cognitive defic...
Expectancy Effects, Failure of Blinding Integrity, and Placebo Response in Trials of Treatments for Psychiatric Disorders: A Narrative Review [0.03%]
精神障碍治疗试验中的预期效果、设盲诚信失效和安慰剂反应的叙述性评论
Nathan T M Huneke,Guilherme Fusetto Veronesi,Matthew Garner et al.
Nathan T M Huneke et al.
Importance: Expectancy effects are significant confounding factors in psychiatric randomized clinical trials (RCTs), potentially affecting the interpretation of study results. This narrative review is the first, to our kn...
Olivia Metcalf,David Forbes
Olivia Metcalf
Circulating Blood-Based Proteins in Psychopathology and Cognition: A Mendelian Randomization Study [0.03%]
精神病学和认知中的循环血液蛋白成分：一项孟德尔随机化研究
Upasana Bhattacharyya,Jibin John,Max Lam et al.
Upasana Bhattacharyya et al.
Importance: Peripheral (blood-based) biomarkers for psychiatric illness could benefit diagnosis and treatment, but research to date has typically been low throughput, and traditional case-control studies are subject to po...
Accelerated Theta-Burst Stimulation for Treatment-Resistant Depression: A Randomized Clinical Trial [0.03%]
加速θ爆发刺激治疗难治性抑郁症：一项随机临床试验
Matheus Rassi F Ramos,Stephan Goerigk,Valquiria Aparecida da Silva et al.
Matheus Rassi F Ramos et al.
Importance: Intermittent theta-burst stimulation (iTBS) is an established treatment for treatment-resistant depression (TRD). Sessions conducted more than once daily (ie, accelerated TBS [aTBS]) may enhance antidepressant...
Joshua B Grubbs,Alexander J Connolly,Scott Graupensperger et al.
Joshua B Grubbs et al.
Importance: Sports gambling has become one of the most accessible forms of gambling in the United States, and recent research suggests that sports gambling coupled with frequent alcohol use may have deleterious health con...